Automatic Injector

• US 20070265568A1
• Filed: 11/04/2005
• Published: 11/15/2007
• Est. Priority Date: 11/04/2004
• Status: Abandoned Application

• Current Assignee: Gilad Lavi, Izrail Tsals
• Original Assignee: Gilad Lavi, Izrail Tsals
• Inventors: Lavi, Gilad, Tsals, Izrail
• Application Number:
  US11/666,851
• Publication Number:
  US 20070265568A1
• Time in Patent Office: Days
• US Class Current: 604/136
• CPC Class Codes: A61M 2005/206 With automatic needle insertion
• CPC Class Codes: A61M 2005/2073 preventing premature release, e.g. by making use of a safety lock
• CPC Class Codes: A61M 2005/3247 Means to impede repositioning of protection sleeve from needle covering to needle uncovering position
• CPC Class Codes: A61M 2205/59 Aesthetic features, e.g. distraction means to prevent fears of child patients
• CPC Class Codes: A61M 5/2033 Spring-loaded one-shot injectors with or without automatic needle insertion multishot dosing syringes A61M5/31525, needle insertion only A61M5/3287
• CPC Class Codes: A61M 5/3204 Needle cap remover, i.e. devices to dislodge protection cover from needle or needle hub, e.g. deshielding devices
• CPC Class Codes: A61M 5/326 Fully automatic sleeve extension, i.e. in which triggering of the sleeve does not require a deliberate action by the user

Abstract

An injector is automatic in that the needle insertion into the injection site (e.g., a patient'"'"'s skin) is triggered by the user or caregiver, the insertion is automatic, the following delivery is automatically initiated upon needle insertion, and the needle is shielded automatically after the end of delivery. Preferably the user does not see the needle prior to, during, or after injection. The injector includes a proximal and distal housings and a needle shield arranged to slide on the distal housing. The injector has a driver arranged to move the syringe to cause the needle penetration, to inject the drug, and subsequently to release the shield. The syringe needle is shielded and the shield locked automatically after delivery is completed. The patient does not experience any injector force on the tissue during injection. The injector has built in patient safety features.

Claims

1. An automatic injector for delivering a dose of medicament into a user'"'"'s body at an injection site, comprising:

a housing having a proximal end and a distal end;

a syringe assembly movably supported within the housing, the syringe assembly including a syringe barrel having an open end and a closed end, a plunger assembly including a stopper, and an injection needle;

a drive member operably and releasably coupled with the syringe barrel and movable between a retracted position and an extended position;

a drive spring operably coupled to the drive member to bias the drive member into the extended position;

a trigger mechanism including a latch capable of retaining the drive member in the retracted position against a force of the drive spring;

at least one mechanical stop connected to the housing, limiting movement of the syringe assembly toward the distal end of the housing to a maximally extended position;

wherein;

activation of the trigger mechanism causes movement of the latch to release the drive member retained in the retracted position, and the drive spring forces the drive member, and the syringe assembly releasably coupled thereto, to move toward the distal end of the housing from the retracted position toward the extended position, forcing the needle to puncture the user'"'"'s body at the injection site;

as the needle punctures the user'"'"'s body, a resistive force acts upon the needle, and upon one of the syringe barrel contacting the mechanical stop and resistive force reaching a predetermined level, the drive member disengages the syringe barrel and additional movement of the syringe barrel and the needle coupled thereto in the direction of the distal end of the housing is prevented; and

with the drive member disengaged from the syringe barrel, the drive spring forces continued movement of the drive member in the direction of the distal end of the housing, forcing the drive member into engagement with the syringe plunger assembly, and forcing the plunger assembly to expel the medicament contained within the syringe barrel through the needle into the user'"'"'s body.

2. The automatic injector of claim 1, wherein the drive member extended position corresponds to engagement of the stopper with the closed end of the syringe barrel, and wherein the drive member drivingly engages the plunger assembly until the drive member reaches the extended position.

3. The automatic injector of claim 1, the syringe barrel including a flange and the drive member including a protrusion engaging the flange, wherein upon application of the resistive force of a predetermined level, the flange rides over the protrusion to disengage the syringe barrel from the drive member.

4. The automatic injector of claim 3, wherein with the syringe assembly in the maximally extended position, the at least one mechanical stop engages the syringe flange to prevent further movement of the syringe assembly toward the distal end of the housing.

5. The automatic injector of claim 1, further comprising a dampening spring operably coupled to one of the drive member and the syringe plunger and positioned between the drive member and the syringe plunger.

6. The automatic injector of claim 5, wherein as the drive member moves into the extended position, the stopper is separated from the closed end of the syringe barrel, and the dampening spring drivingly engages the plunger assembly to force the stopper into engagement with the closed end.

7. The automatic injector of claim 1, wherein the housing is formed from a cylindrical proximal housing portion and a cylindrical distal housing portion fixedly joined together.

8. The automatic injector of claim 1, wherein the housing is fabricated from a substantially clear material allowing the user to see through the housing.

9. The automatic injector of claim 1, further comprising at least one window formed in the housing providing the user with visual access to an interior of the housing.

10. The automatic injector of claim 1, the trigger mechanism further comprising a safety latch capable of being manually bent from a latching position wherein the latch prevents activation of the trigger mechanism into an activated position wherein the latch does not prevent activation of the trigger mechanism.

11. The automatic injector of claim 1, further comprising a needle cap remover extending from the distal end of the housing to facilitate manual removal of a needle cap.

12. The automatic injector of claim 1, wherein the drive spring and the syringe barrel are arranged coaxially within the housing.

13. The automatic injector of claim 1, wherein the syringe assembly is a standard, commercially-available, off-the-shelf syringe assembly.

14. An automatic injector for delivering a dose of medicament into a user'"'"'s body at an injection site, comprising:

a housing having a proximal end and a distal end;

a syringe assembly movably supported within the housing, the syringe assembly including a syringe barrel adapted to contain the medicament, a plunger assembly, and an injection needle;

a drive member operably and releasably coupled with the syringe barrel and movable between a drive member retracted position and a drive member extended position;

a drive member drive spring operably coupled to the drive member to bias the drive member in the drive member extended position;

a trigger mechanism including a drive member latch capable of retaining the drive member in the drive member retracted position against the force of the drive member drive spring;

a shield operably and movably coupled to the distal end of the housing and movable between a shield retracted position and a shield extended position;

a shield drive spring operably coupled to the shield to bias the shield member into the shield extended position;

a first shield latch adapted to engage the shield and capable of retaining the shield in the shield retracted position against the force of the shield drive spring;

wherein

activation of the trigger mechanism causes movement of the drive member latch to release the drive member retained in the drive member retracted position, and the drive member drive spring forces the drive member, and the syringe assembly releasably coupled thereto, to move toward the distal end of the enclosure from the drive member retracted position toward the drive member extended position, forcing the needle to puncture the user'"'"'s body at the injection site;

at a position intermediate the drive member retracted position and the drive member extended position, the drive member contacts the first shield latch to move the first shield latch to release the shield from the shield retracted position; and

the shield spring moves the shield from the shield retracted position to the shield extended position as the drive member drive spring moves the drive member from the drive member intermediate position to the drive member extended position.

15. The automatic injector of claim 14, further comprising a second shield latch adapted to engage the shield positioned in the shield extended position and to retain the shield in the shield extended position.

16. The automatic injector of claim 14, wherein as the shield spring moves the shield from the shield retracted position to the shield extended position, the shield is moved toward the housing distal end, urging the shield toward the user'"'"'s body with a force of the shield spring being sufficient to extract the needle from the user'"'"'s body.

17. The automatic injector of claim 16, wherein the drive member, drive member drive spring, syringe assembly, shield and shield drive spring are configured such that substantially all of the medicament contained within the syringe barrel is injected into the user'"'"'s body before the needle is extracted from the user'"'"'s body.

18. The automatic injector of claim 17, wherein the drive member intermediate position is sufficiently proximate the extended position that there is substantially no force applied to the user'"'"'s body by the shield spring during injection of the medicament into the user'"'"'s body.

19. The automatic injector of claim 14, wherein the shield spring and the shield are arranged coaxially within the housing.

20. The automatic injector of claim 14, wherein the syringe assembly is a standard, commercially-available, off-the-shelf syringe assembly.

21. An automatic injector for delivering a dose of medicament into a user at an injection site, comprising:

a housing having a proximal end and a distal end;

a syringe assembly movably supported within the housing, the syringe assembly including a syringe barrel adapted to contain the medicament, a plunger assembly, and an injection needle;

a drive member operably and releasably coupled with the syringe barrel and movable between a drive member retracted position and a drive member extended position;

a drive member drive spring operably coupled to the drive member to bias the drive member in the drive member extended position;

a trigger mechanism including a drive member latch capable of retaining the drive member in the drive member retracted position against the force of the drive member drive spring;

a shield operably and movably coupled to the distal end of the housing and movable between a shield retracted position and a shield extended position;

a shield drive spring operably coupled to the shield to bias the shield member into the shield extended position;

a first shield latch adapted to engage the shield and capable of retaining the shield in the shield retracted position against the force of the shield drive spring;

at least one mechanical stop connected to the housing, limiting movement of the syringe assembly toward the distal end of the housing to a maximally extended position;

wherein;

activation of the trigger mechanism causes movement of the drive member latch to release the drive member retained in the drive member retracted position, and the drive member drive spring forces the drive member, and the syringe assembly releasably coupled thereto, to move toward the distal end of the enclosure from the drive member retracted position toward the drive member extended position, forcing the needle to puncture the user'"'"'s body at the injection site;

as the needle punctures the user'"'"'s body, a resistive force acts upon the needle, and upon one of the syringe barrel contacting the mechanical stop and resistive force reaching a predetermined level, the drive member disengages the syringe barrel and additional movement of the syringe barrel and the needle coupled thereto in the direction of the distal end of the housing is prevented;

with the drive member disengaged from the syringe barrel, the drive member drive spring forces continued movement of the drive member in the direction of the distal end of the housing, forcing the drive member into engagement with the syringe plunger assembly, and forcing the plunger assembly to expel the medicament contained within the syringe barrel through the needle into the user'"'"'s body until the drive member reaches the extended position;

at a position intermediate the drive member retracted position and the drive member extended position, the drive member contacts the first shield latch to move the first shield latch to release the shield from the shield retracted position; and

the shield spring moves the shield from the shield retracted position to the shield extended position as the drive member drive spring moves the drive member from the drive member intermediate position to the drive member extended position.

22. A method of manufacturing an automatic injector for delivering a fluid, comprising the steps of:

providing a cylindrical proximal housing assembly including a driver member, a driver spring, and a trigger mechanism having a latch, the driver member being retained in a retracted position by the latch;

providing a cylindrical distal housing assembly;

installing a syringe assembly within one of the proximal housing assembly and the distal housing assembly; and

connecting the distal housing assembly to the proximal housing assembly to form an enclosure at least substantially enclosing the syringe assembly such that the syringe assembly is operably engaged with the driver member.

23. The method of manufacturing an automatic injector of claim 22, wherein the step of connecting the distal housing to the proximal housing is accomplished using one of an interference fit, adhesive, and ultrasonic welding.

24. The method of manufacturing an automatic injector of claim 23, wherein the syringe assembly is a standard, commercially-available, off-the-shelf syringe assembly.