Method of treating ACNE with stratum corneum piercing patch

• US 20070270738A1
• Filed: 03/26/2007
• Published: 11/22/2007
• Est. Priority Date: 04/25/2005
• Status: Abandoned Application

• Current Assignee: Danilo Lambino, Jeffrey Wu, Jue Liu, Justin Mcdonough, Mariam Maghribi, Ying Sun
• Original Assignee: Danilo Lambino, Jeffrey Wu, Jue Liu, Justin Mcdonough, Mariam Maghribi, Ying Sun
• Inventors: Sun, Ying, McDonough, Justin, Wu, Jeffrey, Maghribi, Mariam, Liu, Jue, Lambino, Danilo
• Application Number:
  US11/690,960
• Publication Number:
  US 20070270738A1
• Time in Patent Office: Days
• US Class Current: 604/46
• CPC Class Codes: A61B 17/205 Vaccinating by means of needles or other puncturing devices
• CPC Class Codes: A61B 2017/00747 Dermatology

Abstract

The invention features a method of treating acne by piercing the stratum corneum of skin in need of such treatment with a stratum corneum-piercing device that contains at least one stratum corneum-piercing microprotrusion and a compressible cover such that the compressible cover substantially encases the at least one stratum corneum-piercing microprotrusion, and wherein upon contacting the skin with the compressible cover, the at least one stratum corneum-piercing microprotrusion protrudes from the compressible cover and pierces the stratum corneum of the skin.

Claims

1-21. -21. (canceled)

22. A method of treating acne, wherein said method comprises piercing the stratum corneum of skin in need of such treatment with a stratum corneum-piercing patch, said patch comprising at least one stratum corneum-piercing microprotrusion and a compressible cover that is absorbent, wherein said compressible cover substantially encases said at least one stratum corneum-piercing microprotrusion and wherein upon contacting said skin with said compressible cover, said at least one stratum corneum-piercing microprotrusion protrudes from said compressible cover and pierces said stratum corneum of said skin and said patch adheres to said skin.

23. A method of claim 22, wherein said method further comprises applying to said skin a composition comprising an anti-acne active agent proximate to the time of said piercing the stratum corneum of said skin with said stratum corneum-piercing device.

24. A method of claim 23, wherein said anti-acne agent is selected from the group consisting of salicylic acid, retinoic acid, azaleic acid, clindamycin, adapalene, erythromycin, and benzoyl peroxide.

25. A method of claim 24, wherein said patch comprises said composition.

26. A method of claim 25, wherein said composition is contained in said compressible cover.

27. A method of claim 22, wherein said device comprises at least three stratum corneum-piercing microprotrusions.

28. A method of claim 24, wherein said device comprises at least three stratum corneum-piercing microprotrusions.

29. A method of claims 22, wherein said microprotrusions have a length of from about 20 to about 500 microns.

30. A method of claims 24, wherein said microprotrusions have a length of from about 20 to about 500 microns.

31. A method of claims 27, wherein said microprotrusions have a length of from about 20 to about 500 microns.

32. A method of claims 28, wherein said microprotrusions have a length of from about 20 to about 500 microns

33. A kit, said kit comprising:

(a) at least one patch comprising at least one stratum corneum-piercing microprotrusion and a compressible cover that is absorbent such that the compressible cover substantially encases said at least one stratum corneum-piercing microprotrusion; and

(b) a topical composition comprising an anti-acne active agent.

34. A kit of claim 33, wherein said anti-acne agent is selected from the group consisting of salicylic acid, retinoic acid, azaleic acid, clindamycin, adapalene, erythromycin, and benzoyl peroxide.

35. A kit of claim 33, wherein said device comprises at least three stratum corneum-piercing microprotrusions.

36. A kit of claim 34, wherein said device comprises at least three stratum corneum-piercing microprotrusions.

37. A kit of claims 33, wherein said microprotrusions have a length of from about 20 to about 500 microns.

38. A kit of claims 34, wherein said microprotrusions have a length of from about 20 to about 500 microns.

39. A kit of claims 35, wherein said microprotrusions have a length of from about 20 to about 500 microns.

40. A kit of claims 36, wherein said microprotrusions have a length of from about 20 to about 500 microns

41. A kit of claim 33, wherein said kit comprises a skin cleansing product

42. A kit of claim 33, wherein said kit further comprises a film forming composition or a bandage.