Monoclonal Antibodies With Specificity For Fetal Erythroid Cells
First Claim
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1. A monoclonal antibody reacting with a surface antigen present on fetal red blood cells including their nucleated precursor cells, but not with surface antigens on adult erythroid cells.
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Abstract
The present invention concerns a monoclonal antibody and corresponding hybridoma cells and antigens suitable for isolating fetal cells from maternal blood. The monoclonal antibody reacts with a surface antigen present on fetal red blood cells including their nucleated precursor cells, but not with surface antigens on adult erythroid cell.
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Citations
16 Claims
- 1. A monoclonal antibody reacting with a surface antigen present on fetal red blood cells including their nucleated precursor cells, but not with surface antigens on adult erythroid cells.
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4. A hybridoma cell producing monoclonal antibody reacting with a surface antigen present on fetal red blood cells including their nucleated precursor cells, but not with surface antigens on adult erythroid cells.
- 5. A hybridoma cell as deposited under accession number DSM ACC 2666 on Jul. 13, 2004 at the Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH in Braunschweig, Germany.
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6. (canceled)
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8. (canceled)
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10. An antibody characterized in that it recognizes or binds specifically to a surface antigen on fetal red blood cells.
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