Composition Containing a Plant Extract and Process for Producing Same

• US 20070281047A1
• Filed: 10/15/2004
• Published: 12/06/2007
• Est. Priority Date: 10/24/2003
• Status: Active Grant

• Current Assignee: BASF BEAUTY Care Solutions France S.A.S. (BASF SE)
• Original Assignee: Cognis France, S.A.S. (BASF SE)
• Inventors: Henry, Florence, Danoux, Louis, Pauly, Gilles
• Granted Patent: US 8,815,305 B2
• Time in Patent Office: Days
• US Class Current: 424/776
• CPC Class Codes: A61K 2800/782 Enzyme inhibitors; Enzyme antagonists
• CPC Class Codes: A61K 36/185 Magnoliopsida (dicotyledons)
• CPC Class Codes: A61K 8/9789 Magnoliopsida [dicotyledons]
• CPC Class Codes: A61P 17/00 Drugs for dermatological disorders
• CPC Class Codes: A61P 17/16 Emollients or protectives, e.g. against radiation
• CPC Class Codes: A61P 43/00 Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
• CPC Class Codes: A61Q 17/005 Antimicrobial preparations
• CPC Class Codes: A61Q 19/00 Preparations for care of the skin
• CPC Class Codes: A61Q 19/08 Anti-ageing preparations
• CPC Class Codes: A61Q 7/00 Preparations for affecting hair growth

Abstract

A composition which includes a pulp extract from the fruit of Argania spinosa and at least one dermopharmaceutical or cosmetic auxiliary and/or additive is provided. A process for producing an extract from the fruit of Argania spinosa, and a triterpene fraction of an extract of the pulp of the fruit of Argania spinosa including lupeol, α-amyrine, β-amyrine, taraxasterol, and psi-taraxasterol are also provided.

Claims

1. The triterpene-fraction of the extract of the pulp of the fruit of Argania spinosa.

4. A substance selected from the group consisting of the triterpene-fraction according to claim 1, the non-saponifiable-fraction according to claim 2, the extract according to claim 3 and a composition comprising

a) the triterpene-fraction according to claim 1 or the non-saponifiable-fraction according to claim 2 or the extract according to claim 3 and

b) auxiliaries and/or additives which are common for pharmaceutical purposes for treatment of the human or animal body by therapy or diagnostic methods practised on the human or animal body.

5. The use of a substance selected from the group consisting of the triterpene-fraction according to claim 1, the non-saponifiable-fraction according to claim 2, the extract according to claim 3 and a composition comprising

a) the triterpene-fraction according to claim 1 or the non-saponifiable-fraction according to claim 2 or the extract according to claim 3 and

b) auxiliaries and/or additives which are common for pharmaceutical purposes for the manufacture of a medicament for the treatment of human skin that has been damaged by UV-A radiation or by UV-B radiation.

6. A composition comprising

a) an ingredient selected from the group consisting of the triterpene-fraction according to claim 1, the non-saponifiable-fraction according to claim 2, the extract according to claim 3,

lupeol,

α

-amyrine,

β

-amyrine,

taraxasterol and

psi-taraxasterol

and

b) auxiliaries and/or additives which are common for cosmetic purposes.

7. The composition according to claim 6, wherein b) is selected from the group consisting of oily bodies, surfactants, emulsifiers, fats, waxes, pearlescent waxes, bodying agents, thickeners, superfatting agents, stabilizers, polymers, silicone compounds, lecithins, phospholipids, biogenic active ingredients, deodorants, antimicrobial agents, antiperspirants, film formers, antidandruff agents, swelling agents, insect repellents, hydrotropes, solubilizers, preservatives, perfume oils and dyes.

9. The use of the triterpene-fraction according to claim 1 or of the non-saponifiable-fraction according to claim 2 or of the extract according to claim 3 or of lupeol or of α

-amyrine or of β

-amyrine or of taraxasterol or of psi-taraxasterol or of the composition according to any of claims 6 to 7 for the production of a cosmetic preparation.

10. The use of the triterpene-fraction according to claim 1 or of the non-saponifiable-fraction according to claim 2 or of the extract according to claim 3 or of lupeol or of α

-amyrine or of β

-amyrine or of taraxasterol or of psi-taraxasterol or of the composition according to any of claims 6 to 7 or of the cosmetic preparation according to claim 9 for the cosmetic treatment of the human body.

2. The non-saponifiable-fraction of the extract of the pulp of the fruit of Argania spinosa.

3. The extract of the pulp of the fruit of Argania spinosa.

8. A process for the production of the extract according to claim 3 comprising

extracting of the pulp of the fruit of Argania spinosa with a solvent selected from the group consisting of hydrocarbons, halogenated hydrocarbons, alcohols with 1 to 6 carbon atoms, esters of carboxylic acids with 1 to 6 carbon atoms and alcohols with 1 to 6 carbon atoms, ketones with 1 to 6 carbon atoms and supercritical fluids to obtain a mixture comprising the extract and the solvent and

removing the solvent from the mixture thus obtained.