BIOSENSOR FOR MEASUREMENT OF SPECIES IN A BODY FLUID
First Claim
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1. A device comprising:
- a support;
a first electrode disposed on the support;
a second electrode disposed on the support; and
a chamber disposed on the support and comprising a sample area configured to receive a biomarker and a biological recognition element specific for the biomarker, the chamber being in fluid communication with at least one of the first electrode and the second electrode.
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Abstract
Certain embodiments disclosed herein are directed to devices configured to detect the level of a biomarker in a body fluid. In some examples, the device includes two or more electrodes for electrochemical detection of the biomarker in the body fluid. Methods of using the device are also disclosed.
33 Citations
20 Claims
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1. A device comprising:
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a support;
a first electrode disposed on the support;
a second electrode disposed on the support; and
a chamber disposed on the support and comprising a sample area configured to receive a biomarker and a biological recognition element specific for the biomarker, the chamber being in fluid communication with at least one of the first electrode and the second electrode. - View Dependent Claims (2, 3, 4, 5, 6)
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- 7. A device comprising a support and a biological recognition element disposed on the support, the biological recognition element effective to produce an electrochemically detectable reaction product from a body fluid comprising one or more biomarkers indicative of a disease state.
- 14. A point of care device for detecting a biomarker indicative of a disease state, the device configured to receive a body fluid and comprising a biological recognition element effective to convert a biomarker in the body fluid into an electrochemically detectable reaction product.
- 18. A method of detecting a biomarker in a body fluid, the method comprising exposing the biomarker to a biological recognition element disposed in a device comprising at least one electrode, and detecting a reaction product after conversion of the biomarker into the reaction product by the biological recognition element.
Specification