Bioanalytical instrumentation using a light source subsystem
First Claim
1. A method of analyzing one or more analyte comprising:
- (a) directing luminescence from of one or more wavelength from a light pipe including one or more luminescent material onto the one or more analyte; and
(b) directing light emitted from the one or more analyte onto one or more light detector to analyze the one or more analyte.
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Accused Products
Abstract
The invention relates to a light source for irradiating molecules present in a detection volume with one or more selected wavelengths of light and directing the fluorescence, absorbance, transmittance, scattering onto one or more detectors. Molecular interactions with the light allow for the identification and quantitation of participating chemical moieties in reactions utilizing physical or chemical tags, most typically fluorescent and chromophore labels. The invention can also use the light source to separately and simultaneously irradiate a plurality of capillaries or other flow confining structures with one or more selected wavelengths of light and separately and simultaneously detect fluorescence produced within the capillaries or other flow confining structures. In various embodiments, the flow confining structures can allow separation or transportation of molecules and include capillary, micro bore and milli bore flow systems. The capillaries are used to separate molecules that are chemically tagged with appropriate fluorescent or chromophore groups.
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Citations
23 Claims
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1. A method of analyzing one or more analyte comprising:
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(a) directing luminescence from of one or more wavelength from a light pipe including one or more luminescent material onto the one or more analyte; and
(b) directing light emitted from the one or more analyte onto one or more light detector to analyze the one or more analyte. - View Dependent Claims (2)
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3. An apparatus for analyzing one or more analyte comprising:
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(a) relay optics for directing luminescence of one or more wavelengths from one or more light pipes including one or more luminescent material onto one or more analyte;
(b) relay optics for directing emitted light from the one or more analyte onto one or more light detector; and
(c) one or more detector for detecting the presence of the one or more analyte. - View Dependent Claims (4, 5, 6, 7, 8, 9, 10)
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11. A system for identifying one or more analyte comprising:
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(a) directing the flow of the one or more analyte into one or more detection volume;
(b) directing luminescence of one or more wavelengths from one or more light pipe including one or more luminescence material through relay optics onto the one or more analyte;
(c) directing emitted light from the one or more analyte in the detection volume through relay optics onto one or more light detector;
(d) detecting the emitted light of the one or more analyte using one or more light detector; and
(e) identifying a characteristic of the one or more analyte based on the light emitted from the one or more analyte. - View Dependent Claims (12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23)
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Specification