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Acousto-Mechanical Detection Systems and Methods of Use

  • US 20070281369A1
  • Filed: 12/17/2004
  • Published: 12/06/2007
  • Est. Priority Date: 12/30/2003
  • Status: Abandoned Application
First Claim
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1. A system for detecting a target biological analyte, the system comprising:

  • a surface acoustic wave sensor comprising a detection surface;

    a capture agent located on the detection surface, wherein the capture agent is capable of selectively attaching the target biological analyte to the detection surface;

    a detection chamber located within an interior volume of a housing, the detection chamber comprising a volume defined by the detection surface and an opposing surface spaced apart from and facing the detection surface, wherein the opposing surface of the detection chamber comprises a flow front control feature;

    a waste chamber located within the interior volume of the housing, the waste chamber in fluid communication with the detection chamber;

    means for driving the shear horizontal surface acoustic wave sensor;

    means for analyzing data from the surface acoustic wave sensor to determine if target biological analyte is coupled to the capture agent.

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