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Phosphoramidite Compound And Method For Producing Oligo-Rna

  • US 20070282097A1
  • Filed: 08/25/2005
  • Published: 12/06/2007
  • Est. Priority Date: 08/26/2004
  • Status: Active Grant
First Claim
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1. :

  • A phosphoramidite compound represented by general formula (1), Wherein;

    BX represents a nucleobase optionally having a protecting group;

    R1 is a substituent represented by general formula (2), wherein;

    R11, R12, and R13 are the same or different and each represents hydrogen or alkoxy;

    R2a and R2b are the same or different and each represents alkyl, or R2a and R2b taken together with the adjacent nitrogen atom may form a 5- to 6-membered saturated amino cyclic group, the amino cyclic group optionally having an oxygen or sulfur atom as a ring-composing member in addition to the adjacent nitrogen atom; and

    WG1 and WG2 are the same or different and each represents an electron-withdrawing group.

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