Method and device for the identification of at least two substances of content of a body fluid

• US 20070282183A1
• Filed: 04/12/2007
• Published: 12/06/2007
• Est. Priority Date: 04/12/2006
• Status: Abandoned Application

• Current Assignee: Weinmann Gerate Fur Medizin GmbH & Co. KG
• Original Assignee: Weinmann Gerate Fur Medizin GmbH & Co. KG
• Inventors: Scholler, Bernd, Bernstein, Michael, Feldhahn, Karl-Andreas, Forstner, Klaus
• Application Number:
  US11/787,104
• Publication Number:
  US 20070282183A1
• Time in Patent Office: Days
• US Class Current: 600/328
• CPC Class Codes: A61B 2562/0233 Special features of optical sensors or probes classified in A61B5/00
• CPC Class Codes: A61B 2562/046 in a matrix array
• CPC Class Codes: A61B 5/14551 for measuring blood gases
• CPC Class Codes: A61B 5/6826 Finger
• CPC Class Codes: A61B 5/6838 Clamps or clips
• CPC Class Codes: G01N 2021/3144 for oxymetry
• CPC Class Codes: G01N 2021/3148 using three or more wavelengths
• CPC Class Codes: G01N 2021/3181 using LEDs
• CPC Class Codes: G01N 21/314 with comparison of measurements at specific and non-specific wavelengths dual wavelength spectrometry G01J3/427
• CPC Class Codes: G01N 2201/0627 Use of several LED's for spectral resolution

Abstract

A method and a device for the identification of at least two substances of content of a body fluid, wherein adjacent to a body tissue containing the body fluid, are arranged at least one radiation source and a photo receiver. The radiation source generates radiation of two different wavelengths. The radiation is directed onto the body tissue and the photo receiver receives radiation reflected by the body tissue and/or reduced through the body tissue. At least at times the radiation of a third wavelength is directed onto the body tissue for the identification of a hemoglobin derivate.

Claims

1. Method for the identification of at least two substances of content of a body fluid, the method comprising arranging adjacent to a body tissue containing the body fluid at least one radiation source and a photo receiver, wherein the radiation source generates radiation of at least two different wavelengths, directing the radiation onto the body tissue, the photo receiver receiving radiation that is reflected by the body tissue and/or receiving radiation that is reduced through the body tissue, further comprising at least temporarily directing radiation of a third wavelength onto the body tissue for the identification of a hemoglobin derivate.

2. The method according to claim 1, wherein at least three separate radiation sources are used.

3. The method according to claim 1, wherein at least two radiation sources emit at essentially the same wavelength range.

4. The method according to claim 1, wherein successively at least three wavelengths and 4 LED are used.

5. The method according to claim 1, wherein successively four wavelengths and 6 LED are used.

8. The method according to claim 1, wherein at least two radiation sources emit an essentially equal wavelength and the intensity of the one wavelength range is increased by simultaneous use of both radiation sources.

9. A device for the execution of the method according to claim 1 for the identification of at least two substances of content of a body fluid which has at least one radiation source for the generation of radiation of two wavelengths, wherein the radiation source and the photo receiver are equipped with a clamping arrangement for positioning in the area of a body tissue containing a body fluid, and wherein the radiation source emits at least temporarily radiation of a third wavelength.

10. The device according to claim 1, wherein the radiation sources are constructed. as radiation emitting diodes (LED).

11. The device according to claim 10, wherein a plurality of LED with different wavelengths is arranged in a common housing.

12. The device according to claim 10, wherein the light emitting diodes can be activated separately.

13. The device according to claim 10, wherein at least two LED emit in the red spectrum range.

14. The device according to claim 10, wherein at least two LED emit in the infrared spectrum range.

15. The device according to claim 10, wherein at least one LED emits in the range of a wavelength at which high water absorption is present.

16. The device according to claim 10, wherein two LED emit with a given spectrum for the identification of the oxygen saturation of hemoglobin, and wherein at least temporarily at least one auxiliary LED emits certain spectral portions for the identification of the carbon monoxide saturation of hemoglobin.

17. The device according to claim 10, wherein a main LED emits in a predetermined spectrum, wherein at least one auxiliary LED complements temporarily certain intensities in the area of the spectrum of the main LED.

18. The device according to claim 10, wherein two LED emit at a predetermined spectrum for the identification of the oxygen saturation of hemoglobin, and wherein at least at times an auxiliary LED emits certain spectral portions for the identification of the hemoglobin concentration.

19. The device according to claim 10, wherein two LED emit at a predetermined spectrum for the identification of the oxygen saturation of hemoglobin, and wherein at least at times an auxiliary LED emits certain spectral portions for the identification of the methemoglobin concentration.

6. A method for the identification of at least two substances of content of a body fluid, the method comprising arranging adjacent to a body tissue containing the body fluid at least one radiation source and a photo receiver, wherein radiation of two different wavelengths is generated by the radiation source, wherein the radiation is directed onto the body tissue and the photo receiver receives radiation reflected by the body tissue or reduced through the body tissue, wherein through control of a user selection and/or through automatic control at least temporarily radiation of a third wavelength is directed onto the body tissue for the identification of the hemoglobin concentration, further comprising directing additionally at least temporarily radiation of a fourth wavelength onto the body tissue for the identification of the carbon monoxide concentration of the hemoglobin.

7. A method for the identification of at least two substances of content of a body fluid, the method comprising arranging adjacent to a body tissue containing the body fluid at least one radiation source and a photo receiver, wherein radiation of two different wavelengths is generated by the radiation source, wherein the radiation is directed onto the body tissue and the photo receiver receives radiation reflected by the body tissue or reduced through the body tissue, wherein through control of a user selection and/or through automatic control at least temporarily radiation of a third wavelength at which water absorbs more strongly than hemoglobin is directed onto the body tissue for the identification of the hemoglobin concentration, further comprising directing additionally at least temporarily radiation of a fourth wavelength in the range of 600 nm to 710 nm onto the body tissue for the identification of a carbon monoxide concentration of the hemoglobin.

20. A method for identifying at least two substances of content of a body fluid, comprising arranging adjacent to a body tissue containing the body fluid at least one radiation source and a photo receiver, wherein the radiation source generates radiation of at least three different wavelengths and the radiation is directed onto the body tissue, wherein the photo receiver receives radiation reflected by the body tissue and/or reduced through the body tissue, wherein selected activation periods and selected deactivation periods are provided for at least one wavelength.

21. The method according to claim 20, wherein, during an activation period, radiation of at least three different wavelengths is directed onto the body tissue, wherein at least one of the at least three wavelengths is present only at times in all n-cycles in the activation period.

22. The method according to claim 20, wherein for the cycles N=2 is valid indefinitely.

23. The method according to claim 21, wherein at least one wavelength has an activation period different from the two other wavelengths.

24. The method according to claim 20, wherein at least for one wavelength the activation period and the deactivation period alternate.

25. The method according to claim 20, wherein at least for one wavelength the activation period and the deactivation period alternate n-cycles.

26. The method according to claim 21, wherein for the cycles N=2 applies indefinitely.

27. The method according to claim 20, wherein for at least one wavelength the deactivation period for one wavelength can be in the time range of three seconds up to one hour.

28. The method according to claim 20, wherein at least for one wavelength the deactivation period of a wavelength can last up to one hour, while at least two further wavelengths are at least at times in an activation period.

29. The method according to claim 20, wherein the activation period for at least one wavelength can last up to one hour.

30. The method according to claim 20, wherein at least for one wavelength the activation period can last up to one hour, while at least two further wavelengths are included at least temporarily in one activation period.

31. The method according to claim 20, wherein the activation periods and the deactivation periods are specifiable for each wavelength.

32. The method according to claim 20, wherein the activation periods and the deactivation periods for at least two wavelengths occur essentially simultaneously.

33. The method according to claim 20, wherein the activation period and/or the deactivation period can be specified by a user for at least one wavelength.

34. The method according to claim 20, wherein for at least one wavelength an activation mode is interrupted by a deactivation mode in order to save operating energy.