Methods & systems for intraoperatively monitoring nerve & muscle frequency latency and amplitude

• US 20070282217A1
• Filed: 06/01/2006
• Published: 12/06/2007
• Est. Priority Date: 06/01/2006
• Status: Abandoned Application

• Current Assignee: Neurophysiological Concepts LLC
• Original Assignee: Neurophysiological Concepts LLC
• Inventors: McGinnis, William J., Metrick, Scott A.
• Application Number:
  US11/445,122
• Publication Number:
  US 20070282217A1
• Time in Patent Office: Days
• US Class Current: 600/546
• CPC Class Codes: A61B 5/389 Electromyography [EMG]
• CPC Class Codes: A61B 5/395 Details of stimulation, e.g. nerve stimulation to elicit EMG response
• CPC Class Codes: A61B 5/4041 Evaluating nerves condition
• CPC Class Codes: A61B 5/4528 Joints A61B5/4533, A61B5/4538 take precedence

Abstract

Methods and systems are provided for neurophysiological assessment, specifically nerve and nerve root conduction frequencies, latencies and amplitudes, with respect to surgical intervention and insult. Real-time trends in waveforms are captured, and warnings of pathological changes reported, displayed and audibilized.

Claims

1. A method for monitoring and assessing the function of an at-risk nerve in a subject during a surgical procedure, comprising the steps of:

a. obtaining a baseline spontaneously occurring electromyography activity (sEMG) recording;

then serially, throughout the procedure, obtaining a plurality of mechanically elicited electromyography activity (mEMG) recordings; and

therefrom obtaining a plurality of real-time mEMG/sEMG comparisons between the serially obtained mEMG recordings and the sEMG recording;

b. obtaining a baseline spontaneously occurring nerve action potential (sNAP) recording;

then serially, throughout the procedure, recording a plurality of mechanically elicited nerve action potential (mNAP) recordings; and

therefrom obtaining a plurality of real-time mNAP/ sNAP comparisons between the serially obtained mNAP recordings and the sNAP recording;

c. serially, throughout the procedure, electrically stimulating a (sciatic) nerve portion and following each act of stimulating, obtaining a plurality of electrically elicited compound muscle action potential (eCMAP) recordings, and a plurality of electrically elicited compound nerve action potential (eNAP) recordings; and

therefrom obtaining a plurality of real-time eCMAP/eCMAP comparisons between the serially obtained eCMAP recordings and a plurality of real-time eNAP/eNAP comparisons between the serially obtained eNAP recordings,

wherein the obtained mEMG, sEMG, mNAP, sNAP, eCMAP, eNAP recordings, and the mEMG/sEMG, mNAP/sNAP, eCMAP/eCMAP and eNAP/eNAP comparisons are displayed by means of one or more of a plurality of real-time trend displays, and a processor adapted and configured to receive and store in a plurality of real-time data acquisition buffers the obtained mEMG, sEMG, mNAP, sNAP, eCMAP, eNAP recordings, and receive and store in a plurality of real-time comparison buffers the mEMG/sEMG, mNAP/sNAP, eCMAP/eCMAP and eNAP/eNAP comparisons, said processor being in communication with said real-time trend displays, and

wherein said real-time trend displays comprise;

one or a plurality of baseline data windows wherein one or more baseline data are displayed;

one or more amplitude waveform windows wherein one or more amplitude waveforms are displayed with respect to time;

one or a plurality of latency waveform windows wherein one or more latency waveforms are displayed with respect to time;

one or a plurality of frequency waveform windows wherein one or more frequency waveforms are displayed with respect to time; and

one or a plurality of real-time digital value analysis windows, wherein recorded analog data converted to digital values are displayed with respect to time, said digital value analysis windows providing a plurality of evaluations in real-time.

2. The method of claim 1, wherein the procedure is performed upon a hip, a shoulder, a knee, a wrist, an elbow or an ankle.

3. The method of claim 1, wherein the at-risk nerve is a nerve selected from the group consisting of the sciatic, the median, the ulnar, the radial, the axillary, the musculocutaneous, the suprascapular, the deep peroneal, the superficial peroneal, the posterior tibial, the sural, and the common peroneal.

4. The method of claim 1, wherein the sEMG and mEMG recordings are obtained at one or more of a muscle selected from the group consisting of the quadriceps, the tibialis anterior, the gastrocnemius, the medial gastrocnemius, the lateral gastrocnemius, the extensor hallucis longus, the abductor, the abductor pollicis brevis, the thenar eminence, the first dorsal interosseous, the extensor indicis proprius, the abductor pollicis longus, the abductor digiti minimi, the pronator teres, the flexor pollicis longus, the flexor carpi radialis, the flexor carpi ulnaris, the extensor digitorum communis, the tricep, the bicep, the deltoid, and the infraspinatus.

5. The method of claim 1, wherein the sNAP, mNAP and eNAP recordings are obtained over one or more of a nerve selected from the group consisting of the medial femoral cutaneous, the lateral femoral cutaneous, the peroneal, the posterior tibial, the median, the ulnar, the radial, the brachial plexus, the axillary, the musculocutaneous, the suprascapular, the sural, the deep peroneal, and the superficial peroneal.

6. The method of claim 1, wherein the eCMAP recordings are obtained at one or more of a muscle selected from the group consisting of the quadriceps, the tibialis anterior, the gastrocnemius, the extensor hallucis longus, the abductor pollicis brevis, the thenar eminence, the first dorsal interosseous, the abductor pollicis, the extensor indicis proprius, the abductor pollicis longus, the abductor digiti minimi, the first dorsal interosseous, the axillary deltoid, the musculocutaneous, the suprascapular, the extensor digitorum communis, the tricep, the extensor digitorum brevis, the peroneus longus, the abductor digiti minimi and the abductor hallucis.

7. The method of claim 1, wherein one or more of the comparisons occurring with respect to time are audibilized.

8. The method of claim 1, wherein said baseline sEMG recording and said baseline sNAP recording are obtained at a time selected from the group consisting of:

before a procedure, during a procedure but before an invasive step, during a procedure following a first invasive step, prior to instrumentation, and post instrumentation.

9. The method of claim 1, wherein one or more recordings are obtained via wireless electrodes.

10. The method of claim 1, wherein the at-risk nerve is located and stimulated with a bipolar wand.

11. The method of claim 10, wherein the bipolar wand is wirelessly powered.

12. The method of claim 1, further comprising using a montage stocking for placement of electrodes, wherein the montage stocking has positioned apertures corresponding to a specific electrode montage, wherein the electrodes are placed on the surface or just beneath the surface of the skin of a subject at the positions of the apertures.

13. The method of claim 1, further comprising using a multi-channel neurophysiologic monitoring system configured to control a plurality electrodes.

14. The method of claim 13, wherein the neurophysiologic monitoring system comprises wireless recording electrodes.

15. A system for monitoring and assessing the function of an at-risk nerve in a subject during a surgical procedure, comprising means for carrying out the method of claim 1.

16. The system of claim 15, wherein the procedure is performed upon a hip, a shoulder, a knee, a wrist, an elbow or an ankle.

17. The system of claim 16, wherein the at-risk nerve is a nerve selected from the group consisting of the sciatic, the median, the ulnar, the radial, the axillary, the musculocutaneous, the suprascapular, the deep peroneal, the superficial peroneal, the posterior tibial, the sural, and the common peroneal.

18. The system of claim 16, wherein the sEMG and mEMG recordings are obtained at one or more of a muscle selected from the group consisting of the quadriceps, the tibialis anterior, the gastrocnemius, the medial gastrocnemius, the lateral gastrocnemius, the extensor hallucis longus, the abductor, the abductor pollicis brevis, the thenar eminence, the first dorsal interosseous, the extensor indicis proprius, the abductor pollicis longus, the abductor digiti minimi, the pronator teres, the flexor pollicis longus, the flexor carpi radialis, the flexor carpi ulnaris, the extensor digitorum communis, the tricep, the bicep, the deltoid, and the infraspinatus.

19. The system of claim 16, wherein the sNAP, mNAP and eNAP recordings are obtained over one or more of a nerve selected from the group consisting of the medial femoral cutaneous, the lateral femoral cutaneous, the peroneal, the posterior tibial, the median, the ulnar, the radial, the brachial plexus, the axillary, the musculocutaneous, the suprascapular, the sural, the deep peroneal, and the superficial peroneal.

20. The system of claim 16, wherein the eCMAP recordings are obtained at one or more of a muscle selected from the group consisting of the quadriceps, the tibialis anterior, the gastrocnemius, the extensor hallucis longus, the abductor pollicis brevis, the thenar eminence, the first dorsal interosseous, the abductor pollicis, the extensor indicis proprius, the abductor pollicis longus, the abductor digiti minimi, the first dorsal interosseous, the axillary deltoid, the musculocutaneous, the suprascapular, the extensor digitorum communis, the tricep, the extensor digitorum brevis, the peroneus longus, the abductor digiti minimi and the abductor hallucis.

21. The system of claim 16, wherein one or more of the comparisons occurring with respect to time are audibilized.

22. The system of claim 16, wherein said baseline sEMG recording and said baseline sNAP recording are obtained at a time selected from the group consisting of:

before a procedure, during a procedure but before an invasive step, during a procedure following a first invasive step, prior to instrumentation, and post instrumentation.

23. The system of claim 16, wherein one or more recordings are obtained via wireless electrodes.

24. The system of claim 16, wherein the at-risk nerve is located and stimulated with a bipolar wand.

25. The system of claim 16, wherein the bipolar wand is wirelessly powered.

26. The system of claim 16, further comprising using a montage stocking for placement of electrodes, wherein the montage stocking has positioned apertures corresponding to a specific electrode montage, wherein the electrodes are placed on the surface or just beneath the surface of the skin of a subject at the positions of the apertures.

27. The system of claim 16, further comprising using a multi-channel neurophysiologic monitoring system configured to control a plurality electrodes.

28. The system of claim 27, wherein the neurophysiologic monitoring system comprises wireless recording electrodes.

29. The system of claim 27, further comprising a subject connection means connected between the subject and the computer and comprising a plurality of receptor sites for inserting multiple stimulating and recording modules, wherein the receptor sites for inserting stimulating modules correlate with placement of stimulating modules on the subject;

and wherein the receptor sites for inserting recording modules correlate with placement of recording modules on the subject.

30. The system of claim 27, further comprising a stimulus switchbox means connected between the subject connection means and an AND converter means, wherein the stimulus switchbox means provides for instrumental control of a plurality of recording and stimulating modules.

31. The system of claim 27, further comprising a software means for generating a deviation from normal warning signal via a visual, audible or electronic means.

32. The system of claim 27, further comprising a software means for providing and displaying an icon on a computer screen responsive to a command by a computer user, wherein the icon appears on the screen and prompts a user to select an option consisting of take a subject history, select a recording protocol, confirm proper module placement, input parameters, record a sequence, analyze data, archive data, or generate a report.