Iontosonic-microneedle biosensor apparatus and methods

• US 20070282246A1
• Filed: 11/15/2006
• Published: 12/06/2007
• Est. Priority Date: 06/05/2006
• Status: Abandoned Application

• Current Assignee: Mit Company Limited (Mit Holdings Limited)
• Original Assignee: Mit Company Limited (Mit Holdings Limited)
• Inventors: Henley, Julian L.
• Application Number:
  US11/599,329
• Publication Number:
  US 20070282246A1
• Time in Patent Office: Days
• US Class Current: 604/19
• CPC Class Codes: A61B 10/0045 Devices for taking samples of body liquids devices for taking blood samples A61B5/15
• CPC Class Codes: A61B 5/14514 using means for aiding extraction of interstitial fluid, e.g. microneedles or suction
• CPC Class Codes: A61B 5/150022 for capillary blood or interstitial fluid
• CPC Class Codes: A61B 5/150083 by vibration, e.g. ultrasound
• CPC Class Codes: A61B 5/150969 Low-profile devices which resemble patches or plasters, e.g. also allowing collection of blood samples for testing
• CPC Class Codes: A61B 5/150984 Microneedles or microblades
• CPC Class Codes: A61N 1/306 Arrangements where at least part of the apparatus is introduced into the body

Abstract

A screening device that screens for the presence or absence of one or more substances in a mammalian body is disclosed. The device includes a plurality of electrodes, and a biosensor assembly having a reference region and at least one sensor region. The reference region includes at least one microneedle and microchannel, and each sensor region includes at least one microneedle and microchannel, and is sensitive to a specific substance. Each sensor microchannel in a respective sensor region includes a specific assay ligand that may bond with the particular substance to be sensed. Also disclosed is a method for the screening for the presence or absence of one or more substances in the mammalian body.

Claims