Method and Device for Calculating a Bolus Amount

• US 20070282299A1
• Filed: 09/07/2006
• Published: 12/06/2007
• Est. Priority Date: 03/08/2004
• Status: Active Grant

• Current Assignee: Roche Diabetes Care Inc. (Roche Holding AG)
• Original Assignee: Roche Diagnostics International AG (Roche Holding AG)
• Inventors: Hellwig, Robert
• Granted Patent: US 8,945,085 B2
• Time in Patent Office: Days
• US Class Current: 604/504
• CPC Class Codes: A61M 2005/14208 with a programmable infusion control system, characterised by the infusion program
• CPC Class Codes: A61M 2230/201 Glucose concentration
• CPC Class Codes: A61M 5/1723 using feedback of body parameters, e.g. blood-sugar, pressure measurement of body parameters A61B5/00
• CPC Class Codes: A61P 5/48 of the pancreatic hormones
• CPC Class Codes: G16H 20/17 delivered via infusion or injection

Abstract

A method for calculating a bolus amount, wherein the bolus amount is calculated according to a basal rate, and a device for calculating a bolus amount according to the method, the device including an input unit used to input an amount of received carbohydrates, a computer coupled to the input unit and at least one interface used to transmit an actual blood glucose value and the value of the actual basal rate to the computer, wherein the at least one interface or another interface transmits a bolus amount calculated by the computer.

Claims

1. A method for calculating an amount of a substance to be delivered as a function of a basal rate.

2. The method as claimed in claim 1, wherein the basal rate is ascertained from a preset amount of a daily requirement.

3. The method as claimed in claim 2, wherein the amount of substance to be delivered is calculated with the aid of a factor used to ascertain, from the basal rate, another factor which indicates the amount of the substance needed to compensate for a preset amount of another substance.

4. The method as claimed in claim 3, wherein the amount of a substance to be delivered is calculated with the aid of a third factor used to ascertain, from the basal rate, a fourth factor which indicates how a result is affected by the amount of substance delivered.

5. The method as claimed in claim 4, wherein in at least one variable parameter is used to calculate the amount of substance to be delivered.

6. The method as claimed in claim 1, wherein at least one preset parameter is used to calculate the amount of substance to be delivered.

7. The method as claimed in claim 1, wherein the time of day is used to calculate the amount of substance to be delivered.

8. The method as claimed in claim 1, wherein an amount of substance that has been previously delivered is taken into account in the calculation of the amount of substance to be delivered.

9. A device for calculating an amount of a substance to be delivered, said device comprising an input for inputting an amount of a second substance, a processor connected to the input, the processor comprising at least one interface by which current values which can be affected by the second substance and the substance to be delivered can be communicated to the processor, wherein the at least one interface or another interface communicates the amount of substance to be delivered.

10. The device as claimed in claim 9, further comprising a measuring device operably coupled to the processor.

11. The device as claimed in claim 9, further comprising a timing unit operably coupled to the processor.

12. The device as claimed in claim 11, further comprising a memory operably coupled to the processor and the timing unit whereby preset parameters can be stored.

13. The device as claimed in claim 9, further comprising a display device operably coupled to the processor.

14. The device as claimed in claim 9, further comprising a delivery device operably coupled to the processor so that information about the amount of substance to be delivered can be exchanged.

15. A method for calculating a bolus amount (Rec), the bolus amount (Rec) being calculated as a function of the basal rate (BR_actual).

16. The method as claimed in claim 15, wherein the actual basal rate is ascertained from a preset amount of the daily insulin requirement.

17. The method as claimed in claim 16, wherein the bolus amount is calculated with the aid of a factor (CF_A) that is used to ascertain, from the basal rate (BR_actual), a factor (A′

_meal) which indicates how many insulin units are needed to compensate for a preset amount of carbohydrate.

18. The method as claimed in claim 17, wherein the bolus amount is calculated with the aid of a factor (CF_D) that is used to ascertain, from the basal rate (BR_actual), a factor (D_correction) which indicates how the blood-glucose value is reduced by one unit of insulin.

19. The method as claimed in claim 15, wherein in at least one variable parameter is used to calculate the bolus amount.

20. The method as claimed in claim 19, wherein the actual blood-glucose value (x_{BG actual}) and/or the amount of carbohydrate consumed or to be consumed (x_{carbohydrates}) are used as variable parameters.

21. The method as claimed in claim 15, wherein at least one preset parameter is used to calculate the bolus amount.

22. The method as claimed in claim 21, wherein the nominal blood-glucose value (B_{BG target}) is used as a preset parameter.

23. The method as claimed in claim 15, wherein the time of day is used to calculate the bolus amount.

24. The method as claimed in claim 15, wherein the amount of insulin that has already been infused is taken into account in the calculation of the bolus amount.

25. A computer program which, when loaded or running on a computer, executes a method for calculating a bolus amount (Rec), the bolus amount (Rec) being calculated as a function of the basal rate (BR_actual).

26. A program storage medium or computer program product carrying the program claimed in claim 25.

27. A device for calculating a bolus amount with an input unit for inputting an amount of carbohydrate (x_{carbohydrates}) consumed, a calculating unit which is connected to the input unit and which has at least one interface by which the current blood-glucose value (x_{BG actual}) and the current basal-rate value (BR_actual) can be transmitted to the calculating unit, and which has an interface for outputting a bolus amount (Rec) ascertained by the calculating unit.

28. The device as claimed in claim 27, further comprising a measuring device for measuring the actual blood-glucose value (x_{BG actual}).

29. The device as claimed in claim 27, further comprising a timing unit connected to the calculating unit so that the time of day can be transmitted to the calculating unit.

30. The device as claimed in claim 27, further comprising a memory connected to the calculating unit and/or a timing unit so that preset parameters for calculating the bolus amount and/or the amount of insulin administered and/or the time course of the basal rate (BR) can be stored.

31. The device as claimed in claim 27, further comprising a display device which is connected to an interface of the calculating unit so that the bolus amount calculated by the calculating unit can be displayed.

32. The device as claimed in claim 27, further comprising an insulin pump connected to the calculating unit so that information about the bolus amount (Rec) and/or the current basal rate (BR_actual) can be exchanged.