Sampler Device

• US 20070282362A1
• Filed: 03/08/2005
• Published: 12/06/2007
• Est. Priority Date: 03/30/2004
• Status: Abandoned Application

• Current Assignee: Phadia AB (Thermo Fisher Scientific Incorporated)
• Original Assignee: Phadia AB (Thermo Fisher Scientific Incorporated)
• Inventors: Berg, Bjorn, Tarnstrom, Anders, Lindskog, Olof
• Application Number:
  US11/547,198
• Publication Number:
  US 20070282362A1
• Time in Patent Office: Days
• US Class Current: 606/181
• CPC Class Codes: A61B 5/150022 for capillary blood or interstitial fluid
• CPC Class Codes: A61B 5/150175 Adjustment of penetration depth
• CPC Class Codes: A61B 5/150213 Venting means
• CPC Class Codes: A61B 5/150236 Pistons, i.e. cylindrical bodies that sit inside the syringe barrel, typically with an air tight seal, and slide in the barrel to create a vacuum or to expel blood
• CPC Class Codes: A61B 5/150259 Improved gripping, e.g. with high friction pattern or projections on the housing surface or an ergonometric shape
• CPC Class Codes: A61B 5/150343 Collection vessels for collecting blood samples from the skin surface, e.g. test tubes, cuvettes sampling from within body cavities A61B5/150015, A61B5/150045
• CPC Class Codes: A61B 5/150435 Specific design of proximal end
• CPC Class Codes: A61B 5/150717 manually removed
• CPC Class Codes: A61B 5/150824 by visual feedback
• CPC Class Codes: A61B 5/15103 Piercing procedure
• CPC Class Codes: A61B 5/1513 comprising linear sliding guides comprising tooth-shaped elements A61B5/15132
• CPC Class Codes: A61B 5/15144 comprising driving means, e.g. a spring, for retracting the piercing unit into the housing

Abstract

A sampler device for extraction, collection and delivery of a blood sample, includes a lancet (50) carried by a piston (40) which is movable in a cylinder (30), a mechanism (60,70) arranged to drive the piston for expelling of the lancet out from the cylinder in the distal direction and subsequently for retraction of the piston and lancet in a proximal direction, opposite to the distal direction, the cylinder being arranged for collection of the blood sample and the piston being controllable by the mechanism to travel in the distal direction upon feeding a sample volume out from the cylinder.

Claims

1. A sampler device for extraction and collection of a capillary blood sample, comprising a lancet carried by a piston which is movable in a cylinder, a mechanism arranged to drive the piston for expelling of the lancet out from the cylinder in a distal direction and subsequently for retraction of the piston and the lancet in a proximal direction, opposite to said distal direction, characterized by said cylinder being arranged for collection of the blood sample, and said piston being controllable by said mechanism to travel in the distal direction for feeding a sample volume out from the cylinder.

2. The sampler of claim 1, wherein the piston and cylinder are arranged in combination to provide the piston a non-frictional travel length in the distal direction upon expelling of the lancet, and a friction-sealed travel length in said distal direction upon feeding of a sample volume.

3. The sampler of claim 1, wherein the piston and cylinder are arranged in combination to provide the piston a friction-sealed travel length in the distal direction upon feeding of a sample volume, said travel length being controllable by said mechanism for feeding a preset volume of the blood sample.

4. The sampler of claim 3, wherein the mechanism is adjustable to control the travel of the piston for feeding preset portions of the blood sample.

5. The sampler of claim 1, wherein the piston is a reflective prism, providing an indication of complete filling of the cylinder by changing its reflectivity when wetted by the liquid sample.

6. The sampler of claim 1, further comprising a push-button acting on the piston in the distal direction and a return spring acting on the piston and the push-button in the proximal direction, a housing enclosing the push-button, the return spring, the cylinder and the piston in coaxial relation, wherein an interlock mechanism is arranged at the interface between the housing and the push-button, controlling a relative movement there between, said interlock mechanism being releasable in response to a pressure applied to the push-button in the distal direction.

7. The sampler device of claim 6, wherein the interlock mechanism is releasable in response to a relative rotation between the push-button and the housing, caused by the pressure applied in the distal direction.

8. The sampler of claim 7, wherein a cam arrangement is arranged at the interface between the housing and the push-button, said cam arrangement being effective for turning the push-button in response to the pressure applied in the distal direction.

9. The sampler of claim 2, wherein the piston carries a radially protruding flange in the distal end of the piston, the cylinder having an inner periphery frictionally in contact with said flange for a first friction-sealed length of the cylinder and the cylinder having an axial portion of increased radius for a second non-sealing length thereof, as viewed in the distal direction, providing a passage for air to escape in the proximal direction upon expelling of the lancet.

10. The sampler of claim 1, wherein an air passage is formed in the proximal end of the cylinder facing the proximal direction, said air passage providing ventilation of the cylinder upon collection of the blood sample.

11. The sampler of claim 3, further comprising a push-button acting on the piston in the distal direction and a return spring acting on the piston and the push-button in the proximal direction, a housing enclosing the push-button, return spring, cylinder and piston in coaxial relation, wherein an interlock mechanism is arranged at the interface between the housing and the push-button, controlling a relative movement there between, said interlock mechanism being adjustable to limit the travel of said piston in the distal direction so as to cover a desired portion of the friction-sealing length of the cylinder upon feeding of a preset sample volume.

12. The sampler of claim 11, wherein a set of parallel grooves of individual lengths are running axially on the periphery of the push-button, said grooves guiding the travel of a heel formed on the housing, said heel being received in one of said grooves in response to a relative rotation between the push-button and the housing.

13. The sampler of claim 5, wherein the piston is shaped in its distal end to reflect incident light admitted through the proximal end of the piston.

14. The sampler of claim 13, further comprising a push-button acting on the piston in the distal direction and a return spring acting on the piston and the push button in the proximal direction, a housing enclosing the push-button, return spring, cylinder and piston in coaxial relation, wherein said push-button comprises a window through which light is admitted to said piston.

15. A sampler device for disposable use, said sampler device comprising:

a housing;

a cylinder, integrally formed with the housing and adapted to collect a blood sample via an opening in a distal end of said cylinder;

a piston movable in the cylinder;

a lancet carried by the piston;

a push-button acting on the piston and effective for driving said piston in the distal direction for expelling of the lancet out from the cylinder;

a return spring acting on the piston and effective for retracting said piston and the lancet in a proximal direction, opposite to said distal direction;

said housing, said push-button, said return spring, said cylinder and said piston arranged in coaxial relation, and

an interlock mechanism at the interface between the housing and the push-button, controlling a relative motion there between, said mechanism being releasable in response to a relative rotation between said push-button and said housing.