Mechanical means for controlling blood pressure

• US 20070287879A1
• Filed: 06/13/2006
• Published: 12/13/2007
• Est. Priority Date: 06/13/2006
• Status: Abandoned Application

• Current Assignee: LG Research Limited Partnership
• Original Assignee: LG Research Limited Partnership
• Inventors: Gelbart, Daniel, Lichtenstein, Samuel Victor
• Application Number:
  US11/451,437
• Publication Number:
  US 20070287879A1
• Time in Patent Office: Days
• US Class Current: 600/16
• CPC Class Codes: A61B 17/12022 Occluding by internal devices, e.g. balloons or releasable wires plugging an opening in the wall of an organ A61B17/0057; occluders for the cervical canal A61F6/146; vas deferens occluders A61F6/20
• CPC Class Codes: A61B 17/12118 for positioning in conjunction with a stent
• CPC Class Codes: A61B 17/12172 having a pre-set deployed three-dimensional shape methods of manufacturing A61B2017/00526
• CPC Class Codes: A61F 2/07 Stent-grafts
• CPC Class Codes: A61F 2/90 characterised by a net-like or mesh-like structure
• CPC Class Codes: A61F 2/94 Stents retaining their form, i.e. not being deformable, after placement in the predetermined place
• CPC Class Codes: A61F 2002/068 Modifying the blood flow model, e.g. by diffuser or deflector
• CPC Class Codes: A61F 2002/30537 adjustable
• CPC Class Codes: A61F 2230/0008 elliptical or oval
• CPC Class Codes: A61F 2250/0004 adjustable
• CPC Class Codes: A61F 2250/0013 for adjusting fluid pressure

Abstract

Making the volume of the arterial system increase elastically with blood pressure reduces high systolic blood pressure peaks. This volumetric elasticity is achieved by the action of a spring controlling the aortic cross-section thus controlling the aortic volume. The spring can be implanted percutaneously. The device is powered by the blood pressure itself and requires no other energy source or control circuits. The device can have an open structure or a sealed-wall structure, the latter also serve to protect against aortic aneurism. Non-linear volumetric elasticity can be used to assist the heart.

Claims

1-12. -12. (canceled)

13. A passive device to control blood pressure, comprising:

at least a first member sized to be received within an inside of a human aorta and to physically engage the inside of the human aorta such that the first member will physically deform a first portion of the human aorta to have a smaller cross sectional area when the first portion of the human aorta is subjected to a diastolic pressure than the first portion of the human aorta would otherwise have if not deformed by the first member.

14. The passive device of claim 13 wherein the first member has a spring constant, the spring constant such that the first cross sectional area of the first portion of the human aorta is smaller than a cross sectional area of the first portion of the human aorta when the first portion of the human aorta is subjected to a systolic pressure.

15. The passive device of claim 14 wherein the first member comprises a material selected from the group consisting of spring tempered stainless steel, series 300 steel, series 400 steel, heat-treated 17-7 steel, plated heat-treated beryllium copper and Nitinol.

16. The passive device of claim 14 wherein the first member includes a first elastic member that has a spring constant, the spring constant such that the first cross sectional area of the first portion of the human aorta is smaller than a cross sectional area of the first portion of the human aorta when the first portion of the human aorta is subjected to a systolic pressure.

17. The passive device of claim 16 wherein the first member is a first elastic ring elastically deformable between a relaxed shape enclosing a relaxed area and an unrelaxed shape enclosing an unrelaxed area, the unrelaxed area less than the relaxed area.

18. The passive device of claim 17 wherein the relaxed shape is more circular than the unrelaxed shape.

19. The passive device of claim 17 wherein the relaxed shape is circular and the unrelaxed shape is oval.

20. The passive device of claim 17, further comprising:

a second elastic ring elastically deformable between a relaxed shape and an unrelaxed shape, the second elastic ring sized to be received within the inside of the human aorta and to physically engage the inside of the human aorta such that the second elastic ring will physically deform a second portion of the human aorta to have a first cross sectional area when the second portion of the human aorta is subjected to the diastolic pressure than the second portion of the human aorta would otherwise have if not deformed by the second elastic ring; and

a first number of elastic link members linking the first and the second elastic rings.

21. The passive device of claim 20, further comprising:

at least one barb extending outwardly from the passive device.

22. The passive device of claim 20, further comprising:

a third elastic ring elastically deformable between a relaxed shape and an unrelaxed shape, the third elastic ring sized to be received within the inside of the human aorta and to physically engage the inside of the human aorta such that the third elastic ring will physically deform a third portion of the human aorta to have a third cross sectional area when the third portion of the human aorta is subjected to the diastolic pressure that is smaller than the third portion of the human aorta would otherwise have if not deformed by the third elastic ring; and

a second number of elastic link members linking the second and the third elastic rings.

23. The passive device of claim 22, further comprising:

a fourth elastic ring elastically deformable between a relaxed shape and an unrelaxed shape, the fourth elastic ring sized to be received within the inside of the human aorta and to physically engage the inside of the human aorta such that the fourth elastic ring will physically deform a fourth portion of the human aorta to have a first cross sectional area when the fourth portion of the human aorta is subjected to the diastolic pressure that is smaller than a cross sectional area that the fourth portion of the human aorta would otherwise have if not deformed by the fourth elastic ring; and

a third number of elastic link members linking the third and the fourth elastic rings.

24. The passive device of claim 17 wherein the first elastic ring includes a first coil and a second coil, the second coil opposed across the first elastic ring from the first coil.

25. The passive device of claim 17, further comprising:

a plurality of additional elastic rings commonly coupled together at respective portions thereof with the first elastic ring.

26. The passive device of claim 13, further comprising:

a connecting spring that connects at least two portions of the first member and biasing the first member to snap into a shape that would increase a volume of the human aorta.

27. The passive device of claim 13 wherein the passive device fits inside a 4 millimeter inner diameter catheter when compressed.

28. The passive device of claim 13 wherein the passive device decreases a volume of the human aorta by between 10 percent and 20 percent when the first portion of the human aorta is subjected to the diastolic pressure.

29. The passive device of claim 13 wherein the passive device decreases a volume of the human aorta by about 60 cubic centiliters.

30. The passive device of claim 13 wherein the passive device is an open wall structure.

31. The passive device of claim 13 wherein first member is sized to physically deform the first portion of the human aorta to have a first cross sectional area when the first portion of the human aorta is subjected to the diastolic pressure, the first cross sectional area being smaller than a cross sectional area that the first portion of the human aorta would have if not deformed by the first member subjected to the diastolic pressure.

32. A method of forming a passive device to control blood pressure, the method comprising:

providing a first member; and

forming the first member into a size and shape to physically engage an inside of the human aorta such that a first portion of the human aorta will be physically deformed to have a relatively smaller cross sectional area when the first portion of the human aorta is subjected to a diastolic pressure than the human aorta would otherwise have.

33. The method of claim 32 wherein providing a first member includes providing one of at least first one of a wire or a ribbon of a spring material.

34. The method of claim 33 wherein forming the first member into a size and shape to physically engage an inside of the human aorta includes forming a first elastic ring from the at least first one of the wire or the ribbon of a spring material.

35. The method of claim 34, further comprising:

providing a second one of at least one of a wire or a ribbon of a spring material; and

forming the second one of at least one of the wire or the ribbon into a second elastic ring sized and shaped to physically engage the inside of the human aorta such that a second portion of the human aorta will be physically deformed to have a relatively smaller cross sectional area when the second portion of the human aorta is subjected to a diastolic pressure than the human aorta would otherwise have; and

connecting the first and the second elastic rings with a number of elastic links.

36. The method of claim 34 wherein forming the first elastic ring includes forming a first loop and a second loop in the first elastic ring, the first and the second loops opposed to one another.

37. The method of claim 34, further comprising:

connecting portions of the first elastic ring with a connecting spring to provide a nonlinear spring constant thereto.

38. The method of claim 34, further comprising:

providing a plurality of additional ones of at least one of a wire or a ribbon of a spring material; and

forming each of the additional ones of at least one of the wire or the ribbon into a plurality of additional elastic rings sized and shaped to physically engage the inside of the human aorta such that a the human aorta will be physically deformed to have a relatively smaller cross sectional area when the human aorta is subjected to a diastolic pressure than the human aorta would otherwise have; and

commonly connecting potions of the first and the additional elastic rings.

39. A passive device to control blood pressure, comprising:

means for physically engaging an inside of the human artery such that a first portion of the human artery will be physically deformed to have a relatively smaller cross sectional area when the first portion of the human artery is subjected to a diastolic pressure than the human artery would otherwise have.

40. The passive device of claim 39 wherein the means comprises a first elastic ring elastically deformable between a relaxed shape and an unrelaxed shape, the first elastic ring sized to be delivered percutaneously.

41. The passive device of claim 40 wherein the first elastic ring is formed from at least one of an elongated wire or an elongated ribbon.

42. The passive device of claim 39 wherein the means comprises a material selected from the group consisting of spring tempered stainless steel, series 300 steel, series 400 steel, heat-treated 17-7 steel, plated heat-treated beryllium copper and Nitinol.

43. The passive device of claim 39 wherein the means comprises a plurality of elastic rings elastically deformable between a relaxed shape and an unrelaxed shape, and a plurality elastic links linking respective pairs of the elastic rings, the elastic rings and the elastic links deformable to be delivered percutaneously as a unit.

44. The passive device of claim 43 wherein at least one of the elastic links forms at least one barb extending outwardly from the passive device.

45. The passive device of claim 39 wherein the means comprises a first elastic ring elastically deformable between a relaxed and an unrelaxed shape, and a connecting spring connecting at least two portions of the first elastic ring to bias the first elastic ring to snap into a shape that would increase a volume of the human artery.

46. The passive device of claim 39 wherein the means includes a first elastic ring that is elastically deformable, the first elastic ring having a first coil therein and a second coil therein, the second coil opposed across the first elastic ring from the first coil.

47. The passive device of claim 39 wherein the means includes a plurality of elastic rings commonly coupled together at respective ends thereof, each of the elastic rings elastically deformable between a relaxed shape and an unrelaxed shape, the elastic rings each sized to be percutaneously delivered within the human.

48. The passive device of claim 39 wherein the human artery is an aorta.

49. A method employing a passive device, comprising:

positioning a catheter bearing a first member in an inside of a human artery; and

implanting the first member sized to be received within the inside of the human artery and to physically engage the inside of the human artery such that the first member will physically deform a first portion of the human artery to have a first cross sectional area when the first portion of the human artery is subjected to a diastolic pressure, that is smaller than the first portion of the human artery would otherwise have.

50. The method of claim 49 wherein implanting a first member includes implanting a first member having a spring constant, the spring constant such that the first cross sectional area of the first portion of the human artery is smaller than a cross sectional area of the first portion of the human artery when the first portion of the human artery is subjected to a systolic pressure.

51. The method of claim 49 wherein implanting a first member includes implanting the first member includes implanting a first elastic member that has a spring constant, the spring constant such that the first cross sectional area of the first portion of the human artery is smaller than a cross sectional area of the first portion of the human artery when the first portion of the human artery is subjected to a systolic pressure.

52. The method of claim 51 wherein implanting a first member includes implanting a first elastic ring elastically deformable between a relaxed shape enclosing a relaxed area and an unrelaxed shape enclosing an unrelaxed area, the unrelaxed area less than the relaxed area.

53. The method of claim 52 wherein the relaxed shape is more circular than the unrelaxed shape.

54. The method of claim 49 wherein implanting a first member includes implanting a first member comprising a material selected from the group consisting of spring tempered stainless steel, series 300 steel, series 400 steel, heat-treated 17-7 steel, plated heat-treated beryllium copper and Nitinol.

55. The method of claim 49 wherein the human artery is an aorta and implanting the first member includes implanitng the first member to physically engage the inside of the aorta.