DEVICE AND METHOD FOR TREATMENT OF MITRAL INSUFFICIENCY

• US 20070288090A1
• Filed: 08/20/2007
• Published: 12/13/2007
• Est. Priority Date: 06/29/1999
• Status: Active Grant

• Current Assignee: Edwards Lifesciences AG (Edwards Lifesciences Corporation)
• Original Assignee: Edwards Lifesciences AG (Edwards Lifesciences Corporation)
• Inventors: Kimblad, Per, Solem, Jan
• Granted Patent: US 7,717,954 B2
• Time in Patent Office: Days
• US Class Current: 623/2.370
• CPC Class Codes: A61B 17/00234 for minimally invasive surgery A61B17/0218, A61B17/0469, A61B17/12013, A61B17/1285, A61B17/29, A61B17/320016 take precedence
• CPC Class Codes: A61B 2017/00243 cardiac
• CPC Class Codes: A61B 2017/00867 shape memory effect for prostheses A61F2210/0014
• CPC Class Codes: A61F 2/2451 Inserts in the coronary sinus for correcting the valve shape
• CPC Class Codes: A61F 2002/826 more than one stent being applied sequentially
• CPC Class Codes: Y10S 623/903 Blood vessel

Abstract

A device for treatment of mitral annulus dilatation comprises an elongate body having two states. In a first of these states the elongate body is insertable into the coronary sinus and has a shape adapting to the shape of the coronary sinus. When positioned in the coronary sinus, the elongate body is transferable to the second state assuming a reduced radius of curvature, whereby the radius of curvature of the coronary sinus and the radius of curvature as well as the circumference of the mitral annulus is reduced.

Claims

1. A medical apparatus for remodeling a mitral valve annulus, comprising:

an elongate body having a proximal end region and a distal end region, the elongate body having a first configuration for delivery via a catheter to a location adjacent a mitral valve annulus, the elongate body having a second configuration for reshaping the mitral valve annulus to improve coaption of the mitral valve leaflets; and

a forming element attached to the elongate body for manipulating the elongate body from the first configuration to the second configuration;

wherein the proximal and distal end regions of the elongate body are configured to be anchored to opposing regions of tissue adjacent the mitral valve annulus and wherein the elongate body urges the opposing regions of tissue together when manipulated to the second configuration.

2. The medical apparatus of claim 1, wherein the forming element is connected to the elongate body at a point of attachment and the forming element is movable relative to the elongate body in order to adjust the elongate body between the first and second configurations.

3. The medical apparatus of claim 2, wherein the forming element is configured to be maneuvered from outside the vein system for adjusting the elongate body.

4. The medical apparatus of claim 1, wherein the elongate body is sized for advancement at least partially into a coronary sinus.

5. The medical apparatus of claim 1, further comprising a coating on the elongate body for avoiding thrombosis.

6. The medical apparatus of claim 1, wherein the apparatus is movable from the first configuration to the second configuration in response to proximal retraction of the forming element.

7. The medical apparatus of claim 1, wherein the apparatus is movable from the first configuration to the second configuration in response to distal movement of the forming element.

8. The medical apparatus of claim 1, further comprising a first stent along the proximal end region of the elongate body and a second stent along the distal end region of the elongate body.

9. The medical apparatus of claim 8, wherein the first and second stents are expandable for engaging a vessel wall.

10. The medical apparatus as in claim 8, wherein the forming element is coupled to the proximal end region of the elongate body.

11. A medical apparatus for remodeling a mitral valve annulus, comprising:

an elongate body having a first anchor and a second anchor, the elongate body having a first configuration for delivery through a catheter and a second configuration for reshaping the mitral valve annulus to improve coaption of the mitral valve leaflets;

wherein the first and second anchors of the elongate body are configured to be fixed to opposing regions of tissue adjacent the mitral valve annulus and wherein the elongate body urges the opposing regions of tissue together when in the second configuration.

12. The medical apparatus of claim 11, wherein the first and second anchors include tissue penetrating members.

14. The medical apparatus of claim 11, wherein the elongate body comprises a generally U-shaped member formed of a resilient material.

13. A medical apparatus for remodeling a mitral valve annulus, comprising an elongate body having a substantially fixed length, the elongate body being sized for insertion at least partially into a coronary sinus, wherein the elongate body is configured to change curvature after insertion into the coronary sinus for exerting a compressive force on the mitral valve annulus.