Spectral domain optical coherence tomography system
First Claim
1. An ophthalmic imaging device comprising:
- an optical coherence tomography (OCT) system including a first light source for generating a first radiation beam;
a fundus imaging system including a second light source generating a second radiation beam;
optics for combining the first and second radiation beams and directing the combined beams into the eye of a patient in a manner such that the OCT system and the fundus imaging system are confocal; and
an iris viewing system including an imaging device and optics for obtaining an image of the iris along an axis common with the combined first and second radiation beams whereby the OCT system and the fundus imaging system can be aligned with the patient'"'"'s eye based on images generated by the iris viewing system and wherein the images generated by the OCT system and the fundus imaging system are aligned.
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Accused Products
Abstract
An ophthalmic imaging device for improved ophthalmic imaging including: an optical coherence scanning device, a fundus imaging device: an iris viewer; a motorized chin rest; an internal test target, and a fixation target device wherein the optical coherence scanning device, the ophthalmic scanning device, the iris viewer, and the fixation target device all share at least one common optical element. The optical coherence device preferably employs a Mach-Zehnder interferometer with an all fiber reference path; monitoring and attenuating power within the reference path. The multiple devices are separately and in combination aligned with the eye. The system includes internal and external calibration and improved image formats.
495 Citations
63 Claims
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1. An ophthalmic imaging device comprising:
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an optical coherence tomography (OCT) system including a first light source for generating a first radiation beam;
a fundus imaging system including a second light source generating a second radiation beam;
optics for combining the first and second radiation beams and directing the combined beams into the eye of a patient in a manner such that the OCT system and the fundus imaging system are confocal; and
an iris viewing system including an imaging device and optics for obtaining an image of the iris along an axis common with the combined first and second radiation beams whereby the OCT system and the fundus imaging system can be aligned with the patient'"'"'s eye based on images generated by the iris viewing system and wherein the images generated by the OCT system and the fundus imaging system are aligned. - View Dependent Claims (2, 3, 4, 5, 6, 7)
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8. An ophthalmic imaging device comprising:
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an optical coherence scanning device;
a fundus imaging device;
an iris viewer;
a motorized chin rest; and
a fixation target device wherein the optical coherence scanning device, the ophthalmic scanning device, the iris viewer, and the fixation target device all share at least one common optical element. - View Dependent Claims (9, 10)
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11. A method for ophthalmic imaging comprising:
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moving the subject to align focus of a first optical device;
aligning a plurality of optical devices while retaining focus alignment of the first optical device;
creating an image of the interior of an eye with an optical coherence scanning device;
creating a fundus image of the posterior of the eye;
creating an image of the iris of the eye; and
projecting a fixation target to be viewed by the eye wherein the optical coherence scanning device, the ophthalmic scanning device, the iris viewer, and the fixation target device are all optical devices and all operate essentially simultaneously. - View Dependent Claims (12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24)
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25. An ophthalmic imaging device comprising:
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an optical coherence scanning device;
a fundus imaging device;
an iris viewer;
an internal test target; and
a fixation target device wherein during an optical examination, the optical coherence scanning device, the ophthalmic scanning device, the iris viewer, and the fixation target device all share at least one common optical element. - View Dependent Claims (26)
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- 27. An optical coherence tomography scanner comprising a longitudinal delay device, an interferometer, a corner cube, and a transverse scanner, wherein the longitudinal delay device lies between the interferometer and the transverse scanner.
- 39. An optical coherence tomography scanner comprising a reference path in fiber and a reference power device within the reference path for setting the reference power.
- 45. An optical coherence tomography scanner comprising a reference path in fiber and a sample path and operating at a wavelength having significant chromatic dispersion mismatch between the reference path and the sample path.
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50. An ophthalmic imaging device comprising:
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a first imaging system having a component conjugate to an image plane in a first region of the eye;
a second imaging system having a component conjugate to an image plane in a second region of the eye;
wherein first and second regions of the eye are at different depths; and
wherein first and second imaging systems share a common portion of an optical path. - View Dependent Claims (51)
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52. A method of generating images of a eye using an optical coherence tomography (OCT) system, said system including a light source for generating a radiation beam and a scanning mechanism for moving the beam to a plurality of positions within an X/Y plane and wherein the OCT system obtains a measurement of a reflectance distribution within the eye as a function of depth (Z) at each X and Y position, said method comprising the steps of:
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obtaining a first set of depth scans a spaced positions along an X axis at a first Y position;
obtaining a second set of depth scans at spaced positions along an X axis at a second Y position near the first Y position and wherein the X positions of the second set of depth scans are offset from the X positions in the first set of depth scans; and
generating a two dimensional slice image along the X axis as a function of depth by treating the measurements as if they were obtained along a common Y position.
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53. A method of generating images of a eye using an optical coherence tomography (OCT) system, said system including a light source for generating a radiation beam and a scanning mechanism for moving the beam to a plurality of positions within an X/Y plane and wherein the OCT system obtains a measurement of a reflectance distribution within the eye as a function of depth (Z) at each X and Y position, said method comprising the steps of:
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scanning the beam generally along the X direction at a particular Y axis position, said Y axis position defining a centerline of the scan, and while scanning the beam, varying the position of the beam on the Y axis about the centerline while obtaining depth scans at spaced X positions; and
generating a two dimensional slice image along the X axis as a function of depth by treating the measurements as if they were obtained along a common Y position.
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54. A method of generating images of a eye using an optical coherence tomography (OCT) system, said system including a light source for generating a radiation beam and a scanning mechanism for moving the beam to a plurality of positions within an X/Y plane and wherein the OCT system obtains a measurement of a reflectance distribution within the eye as a function of depth (Z) at each X and Y position, said method comprising the steps of:
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scanning the beam generally along the line and while scanning the beam, dithering the lateral position of the beam with respect to the line while obtaining depth scans at a plurality of positions; and
generating a two dimensional slice image along the line as a function of depth by treating all the measurements as if they were obtained along said line. - View Dependent Claims (55)
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56. A method of obtaining B-scan data with reduced speckle in optical coherence tomography (OCT) comprising:
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acquiring a plurality of OCT A-scans; and
forming a B-scan from said A-scans, wherein the A-scans within one resolution cell of the B-scan contains a subset of A-scans which are speckle diverse both tangent to and orthogonal to the B-scan at that cell. - View Dependent Claims (57, 58, 59, 60)
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61. A method for improving the long term performance of an ophthalmic scanning device in which a galvanometer is positioned by a motor comprising:
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generating a command to direct the motor driving the galvanometer to a desired position;
characterizing the closed-loop response of the galvanometer to the generating command; and
adjusting one of the command or the closed loop response to achieve a desired galvanometer position. - View Dependent Claims (62, 63)
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Specification