Probe With Asymmetric Balloon

• US 20070293754A1
• Filed: 10/17/2005
• Published: 12/20/2007
• Est. Priority Date: 10/18/2004
• Status: Abandoned Application

• Current Assignee: Topspin Media
• Original Assignee: Topspin Media
• Inventors: Schneid, Nachum, Lewkonya, Gadi, Venkert, Yoav, Bar Lev, Avner
• Application Number:
  US11/665,699
• Publication Number:
  US 20070293754A1
• Time in Patent Office: Days
• US Class Current: 600/423
• CPC Class Codes: A61B 5/02007 Evaluating blood vessel condition, e.g. elasticity, compliance
• CPC Class Codes: A61B 5/055 involving electronic [EMR] or nuclear [NMR] magnetic resonance, e.g. magnetic resonance imaging
• CPC Class Codes: G01R 33/285 Invasive instruments, e.g. catheters or biopsy needles, specially adapted for tracking, guiding or visualization by NMR
• CPC Class Codes: G01R 33/287 involving active visualization of interventional instruments, e.g. using active tracking RF coils or coils for intentionally creating magnetic field inhomogeneities
• CPC Class Codes: G01R 33/3808 Magnet assemblies for single-sided MR wherein the magnet assembly is located on one side of a subject only; Magnet assemblies for inside-out MR, e.g. for MR in a borehole or in a blood vessel, or magnet assemblies for fringe-field MR
• CPC Class Codes: G01R 33/383 using permanent magnets

Abstract

A device adapted to be inserted into a lumen, the device having a longitudinal axis and comprising: a) a support element extending along the longitudinal axis; b) a tool mechanically mounted on the support element and being adapted to be used near a wall of the lumen on at least a first side of the longitudinal axis; and c) element, the balloon having at least one portion that is less radially expandable than at least one other portion of the balloon, at a same axial position along said support element.

Claims

1. A device adapted to be inserted into a lumen, the device having a longitudinal axis and comprising:

a) a support element extending along the longitudinal axis;

b) a tool mechanically mounted on the support element and being adapted to be used near a wall of the lumen on at least a first side of the longitudinal axis; and

c) element, the balloon having at least one portion that is less radially expandable than at least one other portion of the balloon, at a same axial position along said support element.

2. A device according to claim 1, wherein the tool comprises an MRI coil.

3. A device according to claim 1, wherein the tool comprises MRI coil and magnet.

4. A device according to claim 1, wherein the support element is rigid.

5. A device according to claim 1, wherein the balloon surrounds the tool and the support element.

6. A device according to claim 1 wherein the lumen is in the body.

7. A device according to claim 6, wherein the lumen is a portion of the digestive track.

8. A device according to claim 7, wherein the lumen is the rectum.

9. A device according to claim 6, wherein the lumen is a blood vessel.

10. A device according to claim 9, wherein the device with a non-expanded balloon has an outer diameter of less than 1 mm

11. A device according to claim 9, wherein the device with a non-expanded balloon has an outer diameter of less than 2 mm.

12. A device according to claim 9, wherein the device with a non-expanded balloon has an outer diameter of between 2 mm and 4 mm.

13. A device according to claim 1, wherein the tool is configured to perform a diagnostic task.

14. A device according to claim 13, wherein diagnostic task comprises information gathering by NMR.

15. A device according to claim 13, wherein the diagnostic task comprises imaging.

16. A device according to claim 13, wherein the diagnostic task comprises detecting plaque in a blood vessel.

17. A device according to claim 13, wherein the diagnostic task comprises diagnosing one or more characteristics of plaque in a blood vessel.

18. A device according to claim 1, wherein the balloon safely inflates to a range of sizes varying by at least a factor of 2.

19. A device according to claim 18, wherein the range includes 3 mm.

20. A device according to claim 1, wherein the balloon comprises silicone.

21. A device according to claim 20, wherein the balloon comprises a blend of silicone and polyurethane.

22. A device according to claim 1, wherein the balloon is thicker on the first side of the axis.

23. A device according to claim 1, wherein the balloon is coated with a stiffening material on at least the first side of the axis.

24. A device according to claim 23, wherein at least a portion of the balloon on the side of the axis opposite the first side is not coated with the stiffening material.

25. A device according to claim 23, wherein the stiffening material comprises parylene.

26. A device according to claim 1, wherein a heat shrink material is applied to a balloon'"'"'s portion that is less expandable than other portions of the balloon.

27. A device according to claim 26, wherein the heat shrink material comprises PET.

28. A device according to claim 1, also including a sealing element which holds the balloon against the support element in a pressure-tight manner.

41. A method of performing a diagnostic task on the wall of a lumen in the body, comprising:

a) inserting a device according to claim 1 into the lumen;

b) expanding the balloon of the device;

c) performing one or both of a diagnostic and therapeutic task on the wall of the lumen on the first side of the axis, using the device.

42. A method according to claim 41, wherein the diagnostic task comprises diagnostic imaging.

43. A method according to claim 41, the diagnostic task comprises diagnostic NMR.

44. A method according to claim 41, wherein the lumen is a blood vessel.

45. A method according to claim 44, wherein the diagnostic task comprises detecting plaque.

46. A method according to claim 44, wherein the diagnostic task comprises diagnosing one or more characteristics of plaque.

29. A method of manufacturing a device adapted to be inserted into a lumen, the method comprising:

a) placing an elastically expandable balloon around a support element having an axis;

b) masking the balloon asymmetrically, such that a first portion of the balloon is masked more than a second portion of the balloon, said first and second portions extending along the axis.

c) applying a stiffening material to the masked balloon; and

d) unmasking the balloon.

30. A method according to claim 29, wherein the differences in amount of stiffening material applied to different portions of the balloon allow differences in expandability of such different portions, such that an inflated balloon has one portion that is expanded at least 35% more than another.

31. A method according to claim 29, wherein applying a stiffening material comprises vapor depositing the stiffening material onto the masked balloon.

32. A method according to claim 29, wherein the stiffening material is parylene.

34. A method according to claim 29, also including sealing the balloon against the support element.

35. A method according to claim 34, wherein sealing comprises applying glue.

36. A method according to claim 35, wherein the glue comprises a cyanoacrylate.

37. A method according to claim 35, wherein the glue comprises a UV-curable glue.

33. A method of manufacturing a device adapted to be inserted into a lumen, the method comprising:

a) placing an elastically expandable balloon around a support element having an axis;

b) applying a heat-shrink material to the first portion of the balloon; and

c) heating the heat-shrink material as to let it shrink around the first portion of the balloon.

38. A method of manufacturing a device adapted to be inserted into a lumen, the method comprising:

a) fixing a sheet of polymeric material around a support element having an axis;

b) piercing the sheet of polymeric material as to allow an inflation tube extending along the support element to supply an inflating fluid through the pierce,

c) placing an elastic balloon around the pierced sheet of polymeric material; and

d) heat-fusing a first portion of the elastic balloon to an adjacent portion of the pierced sheet of polymeric material, such that upon supplying inflating material through the inflation tube, the first portion of the balloon will not inflate.

39. A method according to claim 38, wherein the sheet of polymeric material comprises a blend of silicone and polyurethane.

40. A method according to claim 38, wherein the sheet of polymeric material and the elastic balloon are made of the same material.

47. A device comprising an asymmetric balloon, MRI coil and magnet.