POST-BIOPSY CAVITY TREATMENT IMPLANTS AND METHODS

• US 20070299541A1
• Filed: 09/05/2007
• Published: 12/27/2007
• Est. Priority Date: 07/25/2003
• Status: Abandoned Application

• Current Assignee: Encapsule Medical, LLC
• Original Assignee: Rubicor Medical Incorporated (Encapsule Medical Devices LLC)
• Inventors: Chernomorsky, Simon, Vetter, James, Chernomorsky, Ary
• Application Number:
  US11/850,033
• Publication Number:
  US 20070299541A1
• Time in Patent Office: Days
• US Class Current: 623/23.72
• CPC Class Codes: A61B 17/0057 Implements for plugging an opening in the wall of a hollow or tubular organ, e.g. for sealing a vessel puncture or closing a cardiac septal defect sutures A61B17/04; closing rectum or urethra near body surface A61F2/0009
• CPC Class Codes: A61B 2017/00654 entirely comprised between the two sides of the opening
• CPC Class Codes: A61B 2090/3908 Soft tissue, e.g. breast tissue
• CPC Class Codes: A61B 2090/3987 Applicators for implanting markers
• CPC Class Codes: A61B 90/39 Markers, e.g. radio-opaque or breast lesions markers
• CPC Class Codes: A61K 49/04 X-ray contrast preparations
• CPC Class Codes: A61L 31/146 Porous materials, e.g. foams or sponges
• CPC Class Codes: A61L 31/18 Materials at least partially X-ray or laser opaque
• CPC Class Codes: A61M 31/005 for contrast media

Abstract

An implant for filling a cavity created by an excisional procedure includes first and second portions. The first portion may include a first collagenous matrix that defines a first selected crosslinking density and the second portion may include a second collagenous matrix that defines a second selected cross-linking density that is different than the first cross-linking density. The first and second cross-linking densities may be selected so as to cause the first and second portions to swell in such a manner that the implant swells into a size and a shape that is similar to the predetermined size and shape of the cavity when the implant is implanted. An aqueous solution may be added to the cavity if the cavity is not sufficiently aqueous to cause the implant to swell.

Claims

1. A method of filling a cavity created by an excisional procedure, the cavity having a predetermined size and shape, the method comprising the steps of:

providing an implant, the implant including at least a first portion and a second portion, the first portion comprising a first collagenous matrix that defines a first selected crosslinking density, the second portion comprising a second collagenous matrix that defines a second selected cross-linking density that is different than the first cross-linking density, the first and second cross-linking densities being selected so as to cause the first and second portions to swell in such a manner that the implant swells into a size and a shape that is similar to the predetermined size and shape of the cavity when the implant is implanted;

implanting the implant within the cavity through an incision;

adding an aqueous solution to the cavity if the cavity is not sufficiently aqueous to cause the implant to swell, and

closing the incision with the implant implanted in the cavity.

2. The method of claim 1, wherein the providing step is carried out with the first portion comprising a plurality of first collagenous fibers, each of the plurality of first collagenous fibers having the first selected crosslinking density.

3. The method of claim 1, wherein the providing step is carried out with the second portion comprising a plurality of second collagenous fibers, each of the plurality of second collagenous fibers having the second selected cross-linking density.

4. An implant for filling a cavity created by an excisional procedure, the cavity having a predetermined size and a shape, the implant comprising:

a first portion including a first collagenous matrix that defines a first selected crosslinking density, and

a second portion including a second collagenous matrix that defines a second selected cross-linking density that is different than the first cross-linking density,

wherein the first and second cross-linking densities are selected so as to cause the first and second portions to swell in such a manner that the implant assumes a size and a shape that is similar to the predetermined size and shape of the cavity when the implant is implanted.

5. The implant of claim 4, wherein the first portion comprises a plurality of first collagenous fibers, each of the plurality of first collagenous fibers having the first selected crosslinking density.

6. The implant of claim 4, wherein the second portion comprises a plurality of second collagenous fibers, each of the plurality of second collagenous fibers having the second selected cross-linking density.