BIOCOMPATIBLE, SURFACE MODIFIED MATERIALS
First Claim
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1. A biomedical device having a hydrophilic gradient surface, wherein the hydrophilic gradient surface comprises (a) a first layer having a first contact angle;
- (b) a second layer having a second contact angle, the second contact angle being less than the first contact angle of the first layer; and
(c) a third layer having a third contact angle, the third contact angle being less than the first and second contact angles of the first and second layers.
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Abstract
A biomedical device having a hydrophilic gradient surface is provided, wherein the hydrophilic gradient surface comprises (a) a first layer having a first contact angle; (b) a second layer having a second contact angle less than the first contact angle of the first layer; and (c) a third layer having a third contact angle less than the first and second contact angles of the first and second layers. A method for increasing hydrophilicity or wettability of a biomedical device having a hydrophilic gradient surface is also provided.
66 Citations
38 Claims
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1. A biomedical device having a hydrophilic gradient surface, wherein the hydrophilic gradient surface comprises (a) a first layer having a first contact angle;
- (b) a second layer having a second contact angle, the second contact angle being less than the first contact angle of the first layer; and
(c) a third layer having a third contact angle, the third contact angle being less than the first and second contact angles of the first and second layers. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19)
- (b) a second layer having a second contact angle, the second contact angle being less than the first contact angle of the first layer; and
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20. A method for increasing hydrophilicity or wettability of a biomedical device having a hydrophilic gradient surface, the method comprising applying to the surface of the biomedical device a hydrophilic gradient coating comprising (a) a first layer having a first contact angle;
- (b) a second layer having a second contact angle, the second contact angle being less than the first contact angle of the first layer; and
(c) a third layer having a third contact angle, the third contact angle being less than the first and second contact angles of the first and second layers. - View Dependent Claims (21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38)
- (b) a second layer having a second contact angle, the second contact angle being less than the first contact angle of the first layer; and
Specification