Assessment of functional status
First Claim
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1. A method of assessing the functional status of an individual comprising:
- providing a visuospatial learning and memory score obtained from an assessment of a visuospatial learning and memory of said individual, and determining from said score a functional status of said individual.
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Abstract
This invention relates to methods of neurocognitive assessment and, in particular, to methods for assessing the ability of individuals, in particular, memory-impaired individuals, to perform daily activities (i.e. functional status).
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Citations
44 Claims
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1. A method of assessing the functional status of an individual comprising:
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providing a visuospatial learning and memory score obtained from an assessment of a visuospatial learning and memory of said individual, and determining from said score a functional status of said individual. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 24, 27)
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13. A method of identifying a compound useful for improving a functional status of an individual having a reduced or impaired memory, the method comprising:
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assessing a visuospatial learning and memory of an individual having a condition characterised by a reduced or impaired memory to produce a first visuospatial learning and memory score for the individual;
determining from said first score the functional status of said individual before administration of a test compound;
administering the test compound to the individual;
assessing the visuospatial learning and memory of said individual to produce a second visuospatial learning and memory score; and
determining from said second score the functional status of said individual following said administration. - View Dependent Claims (15, 16, 17, 18, 19, 20, 21, 22, 23, 25, 28)
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14. A method of identifying a compound for improving a functional status of an individual having a reduced or impaired memory, the method comprising:
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providing a population of individuals having reduced or impaired memories;
assessing a visuospatial learning and memory of each of the individuals to produce a first visuospatial learning and memory score;
determining from said first score the functional status of each individual before an administration of a test compound;
administering the test compound to each individual;
assessing the visuospatial learning and memory of each individual to produce a second visuospatial learning and memory score; and
determining from said second score the functional status of each individual following said administration. - View Dependent Claims (26, 29)
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30. A computer system comprising:
a processor configured to;
perform a visuospatial learning and memory test on a subject, record a plurality of responses by the subject to the test, calculate a visuospatial learning and memory score for the subject based on the plurality of responses, and determine a functional status of the subject based on the visuospatial learning and memory score. - View Dependent Claims (31, 32, 33)
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34. A method for assessing a functional status, comprising:
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assessing a plurality of individuals to determine a plurality of metrics for each of the individuals, wherein the metrics comprise physical characteristics of the individuals;
performing a visuospatial learning and memory test on each of the plurality of individuals to determine a visuospatial learning and memory score for each of the individuals; and
determining a functional status for each of the individuals based on the plurality of metrics and the visuospatial learning and memory score of each individual. - View Dependent Claims (35, 36, 37, 38, 39, 40)
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41. A method for assessing a functional status, comprising:
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determining a first functional status of a subject based on a plurality of metrics related to the subject and results of a visuospatial learning and memory test, administering a test compound to the subject;
determining a second functional status for the subject based on the plurality of metrics and a second visuospatial learning and memory test performed following the administration of the test compound; and
determining the effect of the test compound on the subject based on a difference between the first functional status and the second functional status. - View Dependent Claims (42, 43, 44)
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Specification