METHODS FOR NON-INVASIVE ANALYTE MEASUREMENT
First Claim
1. A method of non-invasively measuring the presence, absence, or concentration of one or more analytes in a tissue of a subject, comprising:
- exposing at least a portion of a tissue of the subject to electromagnetic radiation;
obtaining electromagnetic radiation measurement data of electromagnetic radiation from the tissue;
using a mathematical transformation to filter or smooth the electromagnetic radiation measurement data; and
determining the presence, absence, or concentration of one or more analytes by determining a radiation signature of the filtered or smoothed electromagnetic radiation measurement data;
correlating the radiation signature of the filtered or smoothed electromagnetic radiation measurement data with the presence, absence, or concentration of one or more analytes to determine the presence, absence, or concentration of one or more analytes in the subject.
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Accused Products
Abstract
A method of non-invasively measuring the presence, absence, or concentration of one or more analytes in a tissue of a subject includes exposing at least a portion of a tissue of the subject to electromagnetic radiation; obtaining electromagnetic radiation measurement data of electromagnetic radiation from the tissue; using a mathematical transformation to filter or smooth the electromagnetic radiation measurement data; and determining the presence, absence, or concentration of one or more analytes by determining a radiation signature of the filtered or smoothed electromagnetic radiation measurement data; correlating the radiation signature of the filtered or smoothed electromagnetic radiation measurement data with the presence, absence, or concentration of one or more analytes to determine the presence, absence, or concentration of one or more analytes in the subject.
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Citations
24 Claims
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1. A method of non-invasively measuring the presence, absence, or concentration of one or more analytes in a tissue of a subject, comprising:
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exposing at least a portion of a tissue of the subject to electromagnetic radiation;
obtaining electromagnetic radiation measurement data of electromagnetic radiation from the tissue;
using a mathematical transformation to filter or smooth the electromagnetic radiation measurement data; and
determining the presence, absence, or concentration of one or more analytes by determining a radiation signature of the filtered or smoothed electromagnetic radiation measurement data;
correlating the radiation signature of the filtered or smoothed electromagnetic radiation measurement data with the presence, absence, or concentration of one or more analytes to determine the presence, absence, or concentration of one or more analytes in the subject. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12)
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13. An instrument for non-invasively measuring the presence, absence, or concentration of one or more analytes in a tissue of a subject, comprising:
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a. a radiation source configured to expose at least a portion of the tissue of the subject to electromagnetic radiation;
b. a radiation detector configured to obtain electromagnetic radiation measurement data of electromagnetic radiation from the tissue; and
c. a microprocessor for determining the presence, absence, or concentration of one or more analytes by using a mathematical transformation to filter or smooth the electromagnetic radiation measurement data, determining a radiation signature of the filtered or smoothed electromagnetic radiation measurement data; and
correlating the radiation signature of the filtered or smoothed electromagnetic radiation measurement data with the presence, absence, or concentration of one or more analytes to determine the presence, absence, or concentration of one or more analytes in the subject. - View Dependent Claims (14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24)
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Specification