THERAPY FOR MELANIN RELATED AFFLICTIONS

• US 20080014159A1
• Filed: 07/17/2007
• Published: 01/17/2008
• Est. Priority Date: 04/02/2004
• Status: Abandoned Application

• Current Assignee: Allergan Incorporated (Abbvie Incorporated)
• Original Assignee: Allergan Incorporated (Abbvie Incorporated)
• Inventors: FIRST, ERIC
• Application Number:
  US11/779,095
• Publication Number:
  US 20080014159A1
• Time in Patent Office: Days
• US Class Current: 424/62
• CPC Class Codes: A61K 38/4893 Botulinum neurotoxin (3.4.24.69)
• CPC Class Codes: A61K 8/64 Proteins; Peptides; Derivatives or degradation products thereof
• CPC Class Codes: A61P 17/00 Drugs for dermatological disorders
• CPC Class Codes: A61P 17/02 for treating wounds, ulcers, burns, scars, keloids, or the like
• CPC Class Codes: A61Q 19/02 for chemically bleaching or whitening the skin
• CPC Class Codes: A61Q 19/04 for chemically tanning the skin topical sun or radiation screening or tanning preparations A61Q17/04
• CPC Class Codes: A61Q 5/065 Preparations for temporary colouring the hair, e.g. direct dyes
• CPC Class Codes: A61Q 9/00 Preparations for removing hair or for aiding hair removal

Abstract

Methods for treating melanin related afflictions by local administration of a Clostridial toxin, such as a botulinum toxin, to a patient with a melanin related affliction.

Claims

1. A method for treating a melanin related affliction, the method comprising the step of administering a botulinum toxin to the skin of a patient, thereby treating a melanin related affliction.

2. The method of claim 1, wherein the melanin related affliction is a skin pigmentation disorder.

3. The method of claim 2, wherein the skin pigmentation disorder is treated by increasing the pigmentation of the skin treated so that the treated skin becomes darker.

4. The method of claim 2, wherein the skin pigmentation disorder is treated by decreasing the pigmentation of the skin treated so that the treated skin becomes lighter.

7. The method of claim 1, wherein the melanin related affliction is treated by reducing a size of the melanin influenced affliction.

10. The method of claim 1, wherein the hair color is altered by decreasing the amount of pigmentation in the hair so that the hair becomes lighter.

11. The method of claim 1, wherein the botulinum toxin is selected from the group consisting of botulinum toxin types A, B, C, D, E, F and G.

12. The method of claim 1, wherein the botulinum toxin is a botulinum toxin type A.

13. The method of claim 1, wherein the botulinum toxin is administered in an amount of between about 1 unit and about 3,000 units.

14. The method of claim 1, wherein the administration is by topical or subcutaneous administration of the botulinum toxin.

5. A method for influencing a skin pigmentation, the method comprising the step of administering a botulinum toxin to the skin of a patient, thereby influencing a skin pigmentation.

6. A method for treating a melanin related affliction, the method comprising the step of administering a botulinum toxin to a skin or hair location of a melanin related affliction of a patient, thereby treating the melanin influenced melanin related affliction by reducing a symptom of the melanin related affliction selected from the group of symptoms consisting of pain, inflammation and vascularization.

8. A method for altering hair color, the method comprising the step of administering a botulinum toxin to the hair, thereby altering the hair color.

9. The method of claim 8, wherein the hair color is altered by increasing the amount of pigmentation in the hair so that the hair becomes darker.

15. A hair removal method, the method comprising the step of administering a botulinum toxin to the hair of a patient.