All day rhinitic condition treatment regimen
First Claim
1. A therapeutic regimen comprising:
- a first pharmaceutical dosage form comprising a first therapeutically effective amount of a first antihistamine having H1 receptor activity and a therapeutically effective amount of an anticholinergic;
a second pharmaceutical dosage form comprising a second therapeutically effective amount of a second antihistamine having H1 receptor activity and a therapeutically effective amount of the anticholinergic, wherein the second antihistamine H1 receptor activity is greater than the first antihistamine H1 receptor activity, with the proviso that the second antihistamine is not acrivastine, astemizole, cetirizine, loratadine, mizolastine, desloratidine or fexofenadine;
indicia for distinguishing between the first and second pharmaceutical dosage forms;
wherein the indicia distinguishes the first pharmaceutical dosage form for daytime administration and the second pharmaceutical dosage form for nighttime administration; and
a prepackaged dispenser prefilled with the pharmaceutical dosage forms and comprising the indicia.
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Abstract
A therapeutic regimen and method of treating a rhinitic condition is provided comprising a first pharmaceutical dosage form comprising a first therapeutically effective amount of an antihistamine and a therapeutically effective amount of an anticholinergic; a second pharmaceutical dosage form comprising a second therapeutically effective amount of an antihistamine and a therapeutically effective amount of the anticholinergic, where the second antihistamine has a greater H1 receptor activity or a greater sedative effect than the first antihistamine. The regimen and method comprise indicia for distinguishing between the first and second pharmaceutical dosage forms, wherein the indicia distinguishes the first pharmaceutical dosage form for daytime administration and the second pharmaceutical dosage form for nighttime administration, and a prepackaged dispenser prefilled with the pharmaceutical dosage forms and comprising the indicia.
45 Citations
27 Claims
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1. A therapeutic regimen comprising:
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a first pharmaceutical dosage form comprising a first therapeutically effective amount of a first antihistamine having H1 receptor activity and a therapeutically effective amount of an anticholinergic; a second pharmaceutical dosage form comprising a second therapeutically effective amount of a second antihistamine having H1 receptor activity and a therapeutically effective amount of the anticholinergic, wherein the second antihistamine H1 receptor activity is greater than the first antihistamine H1 receptor activity, with the proviso that the second antihistamine is not acrivastine, astemizole, cetirizine, loratadine, mizolastine, desloratidine or fexofenadine; indicia for distinguishing between the first and second pharmaceutical dosage forms;
wherein the indicia distinguishes the first pharmaceutical dosage form for daytime administration and the second pharmaceutical dosage form for nighttime administration; anda prepackaged dispenser prefilled with the pharmaceutical dosage forms and comprising the indicia. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11)
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12. A method for treating the symptoms of a rhinitic conditions comprising the steps of:
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formulating a rhinitic treatment regimen comprising a first pharmaceutical dosage form comprising a therapeutically effective amount of a first antihistamine having H1 receptor activity and a therapeutically effective amount of an anticholinergic, and a second pharmaceutical dosage form comprising a therapeutically effective amount of a second antihistamine having H1 receptor activity and a therapeutically effective amount of the anticholinergic;
wherein the second antihistamine H1 receptor activity greater than the first antihistamine H1 receptor activity;providing indicia for distinguishing between the first and second pharmaceutical dosage forms;
wherein the indicia distinguishes the first pharmaceutical dosage form for daytime administration and the second pharmaceutical dosage form for nighttime administration; andprefilling a pharmaceutical dispenser with the first and the second pharmaceutical dosage forms and having the indicia in the dispenser. - View Dependent Claims (13, 14, 15, 16, 17, 18, 19, 20, 21, 22)
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23. A therapeutic regimen comprising:
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a first pharmaceutical dosage form comprising a therapeutically effective amount of a first antihistamine and a therapeutically effective amount of an anticholinergic; a second pharmaceutical dosage form comprising a therapeutically effective amount of a second antihistamine and a therapeutically effective amount of the anticholinergic, wherein the second antihistamine has a greater sedative effect than the first antihistamine; indicia for distinguishing between the first and second pharmaceutical dosage forms;
wherein the indicia distinguishes the first pharmaceutical dosage form for daytime administration and the second pharmaceutical dosage form for nighttime administration; anda prepackaged dispenser prefilled with the pharmaceutical dosage forms and comprising the indicia. - View Dependent Claims (24)
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25. A method for treating the symptoms of a rhinitic conditions comprising the steps of:
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formulating a rhinitic treatment regimen comprising a first pharmaceutical dosage form comprising a therapeutically effective amount of a first antihistamine and a therapeutically effective amount of an anticholinergic, and a second pharmaceutical dosage form comprising a therapeutically effective amount of a second antihistamine and a therapeutically effective amount of the anticholinergic;
wherein the second antihistamine has a greater sedative effect than the first antihistamine;providing indicia for distinguishing between the first and second pharmaceutical dosage forms;
wherein the indicia distinguishes the first pharmaceutical dosage form for daytime administration and the second pharmaceutical dosage form for nighttime administration; andprefilling a pharmaceutical dispenser with the first and the second pharmaceutical dosage forms and having the indicia in the dispenser. - View Dependent Claims (26, 27)
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Specification