MULTI-RESERVOIR PUMP DEVICE FOR DIALYSIS, BIOSENSING, OR DELIVERY OF SUBSTANCES
First Claim
1. A pump patch device for drug delivery comprising:
- a substrate which includes a plurality of discrete reservoirs, each reservoir having at least one reservoir opening;
a drug disposed in the reservoirs;
a pump for delivering a carrier fluid through or adjacent to the at least one opening of each of the reservoirs;
a flow channel for receiving and combining the carrier fluid from the pump and the drug from at least one of the reservoirs to form a fluidized drug; and
at least one needle for delivering the fluidized drug into the skin or another biological tissue of a patient.
1 Assignment
0 Petitions
Accused Products
Abstract
A pump patch device is provided for drug delivery. The device may include a substrate having a plurality of discrete reservoirs, each reservoir having a reservoir opening; a drug disposed in the reservoirs; a pump for delivering a carrier fluid through or adjacent to the reservoir openings; a flow channel for receiving and combining the carrier fluid from the pump with the drug from the reservoirs to form a fluidized drug; and a needle for delivering the fluidized drug into the skin or another biological tissue of a patient. A device is provided for use in dialysis that includes a non-disposable module including a pump or pressure generator; and a disposable cassette operably connected to the pump or pressure generator and including a plurality of discrete reservoirs containing drug and sensors. A fluidics connection device is provided that includes a compression cold weld seal for a microfluidic via.
297 Citations
25 Claims
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1. A pump patch device for drug delivery comprising:
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a substrate which includes a plurality of discrete reservoirs, each reservoir having at least one reservoir opening;
a drug disposed in the reservoirs;
a pump for delivering a carrier fluid through or adjacent to the at least one opening of each of the reservoirs;
a flow channel for receiving and combining the carrier fluid from the pump and the drug from at least one of the reservoirs to form a fluidized drug; and
at least one needle for delivering the fluidized drug into the skin or another biological tissue of a patient. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13)
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14. A method for delivering a drug into the skin or another biological tissue of a patient, the method comprising:
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providing a pump patch device that comprises (i) a substrate which includes a plurality of discrete reservoirs, each reservoir having at least one reservoir opening;
(ii) a drug disposed in the reservoirs;
(iii) a pump comprising a carrier fluid supply, (iv) a flow channel, and (v) at least one needle;
inserting the needle into the patient'"'"'s skin or other biological tissue;
pumping the carrier fluid from the pump through or adjacent to the at least one opening of each of the reservoirs;
combining in the flow channel the carrier fluid from the pump with the drug from at least one of the reservoirs to form a fluidized drug; and
pumping the fluidized drug through the needle and into the patient. - View Dependent Claims (15, 16, 17)
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18. A device for use in dialysis comprising:
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a non-disposable module which comprises a pump or pressure generator;
a disposable cassette operably connected to the pump or pressure generator, wherein the cassette includes a plurality of discrete reservoirs, each having at least one reservoir opening, reservoir contents located in the reservoirs, which reservoir contents comprise a drug, a sensor or sensor component, or a combination thereof, and a plurality of discrete reservoir caps, each cap closing the at least one reservoir opening of each reservoir; and
power and control electronics for actively and selectively disintegrating the reservoir caps to expose the reservoir contents to a physiological fluid, a dialysate, or a combination thereof. - View Dependent Claims (19, 20, 21)
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22. A fluidics connection device comprising:
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a first substrate portion which comprises a seating surface, an opposing surface, and at least one microfluidic via therethrough;
a nipple connector which comprises sealing surface and at least one fluid aperture therethrough; and
a compression cold weld seal which attaches the sealing surface of the first substrate portion to the sealing surface of the nipple connector, such that the microfluidic via is aligned in fluid communication with the fluid aperture. - View Dependent Claims (23, 24, 25)
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Specification