Electroporation Vascular Device and Method

• US 20080015628A1
• Filed: 07/11/2007
• Published: 01/17/2008
• Est. Priority Date: 04/27/1998
• Status: Abandoned Application

• Current Assignee: Artemis Medical, Inc. (Johnson & Johnson)
• Original Assignee: Artemis Medical, Inc. (Johnson & Johnson)
• Inventors: Dubrul, William, Fulton, Richard
• Application Number:
  US11/776,257
• Publication Number:
  US 20080015628A1
• Time in Patent Office: Days
• US Class Current: 606/200
• CPC Class Codes: A61F 2/90 characterised by a net-like or mesh-like structure
• CPC Class Codes: A61F 2/958 Inflatable balloons for placing stents or stent-grafts
• CPC Class Codes: A61F 2250/0067 Means for introducing or releasing pharmaceutical products into the body
• CPC Class Codes: A61L 2300/416 Anti-neoplastic or anti-proliferative or anti-restenosis or anti-angiogenic agents, e.g. paclitaxel, sirolimus
• CPC Class Codes: A61L 29/16 Biologically active materials, e.g. therapeutic substances A61L29/048 takes precedence
• CPC Class Codes: A61M 2025/0057 Catheters delivering medicament other than through a conventional lumen, e.g. porous walls or hydrogel coatings
• CPC Class Codes: A61M 2025/1052 for temporarily occluding a vessel for isolating a sector
• CPC Class Codes: A61M 2025/1081 having sheaths or the like for covering the balloon but not forming a permanent part of the balloon, e.g. retractable, dissolvable or tearable sheaths
• CPC Class Codes: A61M 25/10 Balloon catheters A61M25/0125 takes precedence; embolectomy A61B17/22032; retractors A61B17/02; inflatable balloons for placing stents or stent-grafts A61F2/958 ; stomach balloons for treatment of obesity A61F5/0003; oesophagal tubes A61J15/00
• CPC Class Codes: A61M 25/1011 Multiple balloon catheters
• CPC Class Codes: A61M 25/104 used for angioplasty
• CPC Class Codes: A61N 1/306 Arrangements where at least part of the apparatus is introduced into the body
• CPC Class Codes: A61N 1/327 for enhancing the absorption properties of tissue, e.g. by electroporation

Abstract

A particle-removing medical device includes an outer, hollow tube having a tube distal end and a porous braided structure having a distal part and a proximal part. Structure, housed within the tube and having a distal end positioned distally of the tube distal end, is used to move the braided structure from a contracted condition to an expanded condition by moving the distal ends of the tube and the structure towards one another. The braided structure is constructed to inhibit particles from moving completely through the braided structure when in the expanded condition.

Claims

1-21. -21. (canceled)

22. A cardiovascular device, for use in a vascular lumen within a body for treatment of cardiovascular disease, comprising:

a braided body; and

said braided body comprising electroporation means for helping prevent restenosis in a cardiovascular lumen.

23. The device of claim 22 wherein the braided body constitutes an electrode.

24. A method for treating cardiovascular disease comprising:

obtaining a radially expandable and collapsible medical device;

placing the medical device, in a radially collapsed state, within a cardiovascular passageway within a body;

positioning the medical device at a target site within the passageway;

placing the medical device in a radially expanded state;

inhibiting restenosis at the target site by electroporation;

placing the medical device in a radially collapsed state; and

removing the device from the passageway.

25. The method according to claim 24 wherein the radially expanded state placing step takes place after the positioning step.

26. The method according to claim 24 wherein the restenosis inhibiting step is carried out using the device as an electrode.

27. The method according to claim 26 wherein the restenosis inhibiting step is carried out with the aid of a separate programmable device.

28. A method for treating cardiovascular disease comprising:

obtaining a radially expandable and collapsible medical device;

placing the medical device, in a radially collapsed state, within a cardiovascular passageway within a body;

positioning the medical device at a target site within the passageway;

placing the medical device in a radially expanded state;

inhibiting restenosis at the target site by iontophoresis;

placing the medical device in a radially collapsed state; and

removing the device from the passageway.