IMPLANTABLE ELECTRODE DEVICE

• US 20080015643A1
• Filed: 05/24/2007
• Published: 01/17/2008
• Est. Priority Date: 07/12/2006
• Status: Abandoned Application

• Current Assignee: Biotronik CRM Patent AG (Biotronik SE & Company KG)
• Original Assignee: Biotronik CRM Patent AG (Biotronik SE & Company KG)
• Inventors: Geistert, Wolfgang, Bartels, Klaus
• Application Number:
  US11/753,281
• Publication Number:
  US 20080015643A1
• Time in Patent Office: Days
• US Class Current: 607/3
• CPC Class Codes: A61N 1/0563 specially adapted for defibrillation or cardioversion
• CPC Class Codes: A61N 1/0568 with drug delivery

Abstract

An implantable electrode device, in particular an ICD electrode device, comprises an electrode main body and at least one electrode situated thereon, the electrode including a wire material forming undercuts and/or intermediate spaces between its wires, such as a wire braid or an open wire coil. A medication depot filling is introduced into the under-cuts and/or intermediate spaces.

Claims

1. An implantable electrode device comprising an electrode main body having:

a. at least one electrode situated on the electrode main body, the electrode including one or more leads with at least one of

(1) undercuts about the leads, and

(2) intermediate spaces between the leads,

b. a medication depot filling in the undercuts and/or intermediate spaces, wherein the medication depot filling contains a releasable medicinal active ingredient.

2. The electrode device of claim 1 wherein the medication depot filling includes a flexible plastic carrier material wherein the medicinal active ingredient is distributed.

3. The electrode device of claim 1 wherein the medication depot filling at least partially surrounds the leads to prevent the definition of any concavities between each lead and the medication depot filling.

4. The electrode device of claim 1 wherein the leads are at least partially embedded within the medication depot filling.

5. The electrode device of claim 1 wherein the leads are defined by a braid.

6. The electrode device of claim 1 wherein the leads are defined by a coil.

7. The electrode device of claim 1 wherein the medication depot filling is a biocompatible polymer matrix material.

8. The electrode device of claim 7 wherein the medication depot filling includes one or more of

a. silicone and

b. polyurethane.

9. The electrode device of claim 1 wherein the medicinal active ingredient in the medication depot filling includes at least one of:

a. an antiinflammatory agent,

b. an anticoagulant agent, and/or

c. an antiproliferative agent.

10. The electrode device of claim 1 wherein the medication depot filling contains a biodegradable component.

11. The electrode device of claim 1 wherein the medication depot filling is formed by the steps of:

a. mixing a medicinal active ingredient into a liquid carrier material;

b. introducing the mixture into the undercuts and/or intermediate spaces; and

c. curing the mixture.

12. The electrode device of claim 1 wherein the medication depot filling is formed by the steps of:

a. introducing a liquid carrier material into the undercuts and/or intermediate spaces;

b. curing the carrier material into an at least semi-solid state; and

c. introducing the medicinal active ingredient into the cured carrier material.

13. The electrode device of claim 12 wherein the cured carrier material has openings defined therein, the openings being formed by at least one of the steps of:

a. shaping the openings into the carrier material during curing;

b. forming the openings into the cured carrier material; and

c. dissolving matter distributed within the carrier material.

14. The electrode device of claim 12 wherein the medicinal active ingredient is introduced into the cured carrier material by at least one of the steps of:

a. immersing the filling material in a medication solution or suspension; and

b. inserting particles or threads containing active ingredient into openings in the cured carrier material.

15. An implantable electrode device having an electrode main body with:

a. a medication depot filling on a surface of the electrode main body, wherein the medication depot filling includes a medicinal active ingredient;

b. an electrical lead at least partially situated on the surface of the electrode main body, wherein;

(1) at least a portion of the electrical lead abuts the medication depot filling, and

(2) less than half of the surface area of the electrical lead is exposed on the surface of the electrode main body.

16. The implantable electrode device of claim 15 wherein the electrical lead is at least substantially embedded within the surface of the electrode main body, wherein less of the electrical lead extends above the surface of the electrode main body than below the electrode main body.

17. The implantable electrode device of claim 15 wherein an angle defined by the adjoining surfaces of the electrical lead and the medication depot filling is greater than 90 degrees at all areas wherein the electrical lead abuts the medication depot filling.

18. An implantable electrode device having an electrode main body with:

a. a surface at least partially defined by a medication depot filling, wherein the medication depot filling includes a medicinal active ingredient;

b. an electrical lead substantially embedded within the surface of the electrode main body, wherein less of the electrical lead extends above the surface of the electrode main body than below the electrode main body.

19. The implantable electrode device of claim 18 wherein less than half of the surface area of the electrical lead is exposed on the surface of the electrode main body.

20. The implantable electrode device of claim 18 wherein an angle defined by any adjoining surfaces of the electrical lead and the medication depot filling is greater than 90 degrees at all areas wherein the electrical lead extends above the surface of the electrode main body.