Method And Apparatus For Photo-Chemical Oculoplasty/Keratoplasty

• US 20080015660A1
• Filed: 07/11/2007
• Published: 01/17/2008
• Est. Priority Date: 07/13/2006
• Status: Abandoned Application

• Current Assignee: Seros Medical, LLC
• Original Assignee: Priavision, Inc.
• Inventors: Herekar, Satish V.
• Application Number:
  US11/776,470
• Publication Number:
  US 20080015660A1
• Time in Patent Office: Days
• US Class Current: 607/88
• CPC Class Codes: A61F 2009/00872 Cornea
• CPC Class Codes: A61F 9/0079 using non-laser electromagnetic radiation, e.g. non-coherent light or microwaves
• CPC Class Codes: A61N 2005/0654 Lamps
• CPC Class Codes: A61N 2005/0661 ultraviolet
• CPC Class Codes: A61N 5/062 Photodynamic therapy, i.e. excitation of an agent
• CPC Class Codes: A61N 5/1017 Treatment of the eye, e.g. for "macular degeneration"

Abstract

Method and apparatus for performing oculoplasty including applying a photosensitizer solution to a human eye surface includes defining a treatment region within the human eye surface. The treatment region is associated with a predetermined spatial pattern. The method further includes irradiating the treatment region with controlled photoactivating radiation. In relation to presbyopia treatments, shrinkage of the paralimbal scleral region near the scleral spur results in improved near focus with no loss in far acuities.

Claims

1. A method for performing oculoplasty, the method comprising:

applying a photosensitizer solution to a human eye surface;

defining a treatment region within the human eye surface, the treatment region being associated with a predetermined spatial pattern; and

irradiating the treatment region with controlled photoactivating radiation.

2. The method of claim 1 wherein the photoactivating radiation comprises ultraviolet/blue radiation.

3. The method of claim 1 wherein the predetermined spatial pattern is defined by directed transmission of the ultraviolet/blue radiation.

4. The method of claim 3 wherein the irradiating step includes directing the ultraviolet/blue radiation of a predetermined wavelength range, with preselected intensity of a range of radiation intensities, at a plurality of locations within the spatial pattern.

5. The method of claim 4 wherein the irradiating step is carried out through a medium of an array of micro-mirrors.

6. The method of claim 5 wherein micro-mirrors of the array of micro-mirrors yield output at a plurality of selectable gray-scale intensities.

7. The method of claim 1 wherein the photosensitizer comprises a solution including riboflavin.

8. The method of claim 7 wherein concentration of riboflavin ranges from 0.05% to 0.2%.

9. The method of claim 8 wherein the concentration of riboflavin is substantially 0.1%.

10. The method of claim 1 wherein the human eye surface is a corneal region.

11. The method of claim 1 wherein the predetermined spatial pattern is a two-dimensional pattern.

12. The method of claim 11 wherein the two-dimensional pattern comprises a raster scanned pattern.

13. The method of claim 12 wherein the raster scanned pattern comprises at least 1024×

868 pixels.

14. The method of claim 13 wherein a spatial resolution of each micro-mirror is substantially 20 Mm.

15. The method of claim 1 wherein the controlled ultraviolet/blue radiation has a predetermined wavelength range of 350 nm to 380 nm.

16. The method of claim 1 wherein the ultraviolet/blue radiation has an optical fluence of less than 20 mW/cm².

17. The method of claim 16 wherein the optical fluence is less than 15 mW/cm².

18. A method for treating a living tissue, the method comprising:

applying a photosensitizer solution to a surface of the tissue;

defining a treatment region within the surface, the treatment region being associated with a predetermined spatial pattern of intensities; and

irradiating the treatment region with an effective dose of controlled ultraviolet/blue radiation according to the spatial pattern.

19. An apparatus for performing oculoplasty, the apparatus comprising:

an applicator for applying a photosensitizer solution to a human eye surface; and

an illuminator for irradiating a defined treatment region within the human eye surface with an effective amount controlled ultraviolet/blue radiation according to a predetermined spatial pattern of intensities.