WEARABLE ULTRAFILTRATION DEVICE

• US 20080021366A1
• Filed: 07/30/2007
• Published: 01/24/2008
• Est. Priority Date: 11/16/2001
• Status: Active Grant

• Current Assignee: Fresenius Medical Care Holdings Incorporated (Fresenius Medical Care AG)
• Original Assignee: National Quality Care Inc.
• Inventors: GURA, VICTOR, RAMBOD, EDMOND
• Granted Patent: US 7,828,761 B2
• Time in Patent Office: Days
• US Class Current: 604/6.09
• CPC Class Codes: A61M 1/16 with membranes
• CPC Class Codes: A61M 1/1696 with dialysate regeneration
• CPC Class Codes: A61M 1/34 Filtering material out of the blood by passing it through a membrane, i.e. hemofiltration or diafiltration
• CPC Class Codes: A61M 1/3403 Regulation parameters
• CPC Class Codes: A61M 1/3496 Plasmapheresis; Leucopheresis; Lymphopheresis A61M1/3472 takes precedence
• CPC Class Codes: A61M 2205/3331 Pressure; Flow
• CPC Class Codes: A61M 2205/8206 battery-operated
• CPC Class Codes: A61M 2209/082 Mounting brackets, arm supports for equipment
• CPC Class Codes: A61M 2209/088 on the body
• CPC Class Codes: B01D 61/145 Ultrafiltration
• CPC Class Codes: B01D 61/18 Apparatus therefor

Abstract

An ultrafiltration device adapted to be worn on a portion of the body of a patient includes a blood inlet tube leading from a first blood vessel, a blood pump, an anticoagulant reservoir for infusing anticoagulants into the blood, a blood filter including a substrate through which the blood is circulated and filtered, a fluid bag for storing the excess fluid and a blood outlet tube leading to a second blood vessel.

Claims

1. A method of ultrafiltrating excess body fluid from a congestive heart failure patient, the method comprising:

obtaining via a blood inlet tube from a first blood vessel of a congestive heart failure (CHF) patient blood containing excess body fluid;

shuttle-pumping said blood with a shuttle pump;

receiving at an ultrafiltration filter said blood from said shuttle pump and filtering said blood containing excess body fluid with said ultrafiltration filter to remove said excess body fluid from said blood at a rate slow enough to reduce a risk of creating a low blood pressure condition in said CHF patient and slow enough to allow continuous removal of said excess body fluid for at least 24 hours;

directing all of said removed excess body fluid directly to a fluid storage receptacle; and

returning said filtered blood to a second blood vessel of said CHF patient.

2. The method of claim 1, further comprising infusing an anticoagulant into said blood containing excess body fluid prior to filtering said blood containing excess body fluid.

3. The method of claim 1, wherein said shuttle pump, said ultrafiltration filter and said fluid storage receptacle are all completely wearable on said CHF patient and allow said CHF patient to perform normal everyday activities.

4. The method of claim 1, further comprising filtering said blood containing excess body fluid for a period of time long enough to help deter the reaccumulation of excess body fluid in said CHF patient.

5. The method of claim 1, further comprising powering at least said shuttle pump with a wearable power source.

6. A method of ultrafiltrating excess body fluid from a congestive heart failure patient using a completely wearable ultrafiltration device, said method comprising:

receiving, in a blood inlet tube from a first blood vessel of a congestive heart failure patient, blood containing excess body fluid;

shuttle-pumping, with a shuttle pump included in said completely wearable ultrafiltration device, said blood containing excess body fluid from said blood inlet tube to an ultrafiltration filter, said ultrafiltration filter being included in said completely wearable ultrafiltration device;

separating an amount of excess body fluid from said blood containing excess fluid using said ultrafiltration filter, the combination of said shuttle pump and said ultrafiltration filter separate said amount of excess body fluid from said blood containing excess fluid at a rate slow enough to deter blood pressure drops in said CHF patient, at a rate slow enough to allow said completely wearable ultrafiltration device to continually operate for at least 24 hours, and at a rate fast enough to help alleviate the CHF patient'"'"'s symptoms associated with CHF.;

draining all said separated excess fluid from said ultrafiltration filter to an excess fluid receptacle;

returning said filtered blood containing excess body fluid from said ultrafiltration filter to a second blood vessel of said CHF patient; and

powering at least said shuttle pump with a power source, said power source being included in said completely wearable ultrafiltration device.

7. The method of ultrafiltrating excess body fluid from a CHF patient of claim 6, further comprising infusing an anticoagulant into said blood containing excess body fluid prior to separating said amount of excess body fluid from said blood.

8. The method of claim 7, wherein said infusing said anticoagulant comprises pumping said anticoagulant with an anticoagulant pump from an anticoagulant reservoir, said anticoagulant pump and said anticoagulant reservoir included in said completely wearable ultrafiltration device.

9. The method of claim 8, wherein said anticoagulant pump is a piston pump or a piezoelectric pump.

10. The method of claim 6, further comprising wearing said completely wearable ultrafiltration device on the body of said CHF patient continuously for a plurality of days.

11. The method claim 6, further comprising wearing said completely wearable ultrafiltration device about a shoulder of said CHF patient.

12. A method of removing excess body fluids from a CHF patient using a completely wearable, portable and self powered ultrafiltration device;

said method comprises;

installing said completely wearable, portable and self powered ultrafiltration device on a CHF patient;

shuttle-pumping, from a first blood vessel of said CHF patient, fluid overloaded blood;

filtering excess body fluid, from said fluid overloaded blood, through a semiporous material at a rate that can be sustained for at least 24 hours without being a direct cause of a low blood pressure or damage to a vital organ in said CHF patient;

collecting all said filtered excess body fluid; and

returning said filtered fluid overloaded blood to a second blood vessel of said CHF patient.

13. The method of claim 12, wherein said filtering excess body fluid through said semiporous material comprises creating a pressure gradient through said semiporous material.

14. The method of claim 12, wherein said installing said completely wearable, portable and self powered ultrafiltration device comprises installing said completely wearable, portable and self powered ultrafiltration device over said CHF patient'"'"'s shoulder.

15. The method of claim 12, wherein said filtering of said excess body fluid is sustained for a period of time long enough to deter a reaccumulation of said excess body fluid in said CHF patient.