Biomolecule diagnostic devices and method for producing biomolecule diagnostic devices
First Claim
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1. A biosensor, comprising:
- a substrate member;
a photo-reactive agent at a surface of said substrate member;
a receptive material layer applied over said photo-reactive agent and generally uniformly covering said side of said substrate member, said receptive material being specific for an analyte of interest;
a pattern of active and inactive areas of said receptive material defined on said layer, said active and inactive areas formed by a masking process wherein a mask is placed over said substrate member prior to irradiating said substrate member with an energy source sufficient for activating said photo-reactive agent such that areas exposed by said mask define said pattern of inactive areas of said receptive material and said areas shielded by said mask define said pattern of active areas of receptive material; and
wherein when said biosensor is exposed to a medium containing said analyte of interest, the analyte binds to said receptive material in said active areas and subsequently facilitate diffraction of transmitted light or reflected light in a diffraction pattern corresponding to said active areas.
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Abstract
A biosensor includes a substrate with a layer of receptive material disposed thereon overlying a layer containing a photo-reactive agent. The receptive material is specific for an analyte of interest. A pattern of active and inactive areas of the receptive material are defined in the receptive material layer by a masking process wherein the photo-reactive agent is activated in the exposed regions of the mask.
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Citations
11 Claims
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1. A biosensor, comprising:
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a substrate member;
a photo-reactive agent at a surface of said substrate member;
a receptive material layer applied over said photo-reactive agent and generally uniformly covering said side of said substrate member, said receptive material being specific for an analyte of interest;
a pattern of active and inactive areas of said receptive material defined on said layer, said active and inactive areas formed by a masking process wherein a mask is placed over said substrate member prior to irradiating said substrate member with an energy source sufficient for activating said photo-reactive agent such that areas exposed by said mask define said pattern of inactive areas of said receptive material and said areas shielded by said mask define said pattern of active areas of receptive material; and
wherein when said biosensor is exposed to a medium containing said analyte of interest, the analyte binds to said receptive material in said active areas and subsequently facilitate diffraction of transmitted light or reflected light in a diffraction pattern corresponding to said active areas. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11)
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Specification