Methods and Compositions Involving microRNA
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Accused Products
Abstract
The present invention concerns methods and compositions for isolating, enriching, and/or labeling miRNA molecules and for preparing and using arrays or other detection techniques for miRNA analysis. Moreover, the present invention concerns methods and compositions for generating miRNA profiles and employing such profiles for therapeutic, diagnostic, and prognostic applications.
209 Citations
180 Claims
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1-147. -147. (canceled)
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148. A method for identifying a correlation between miRNA expression and a disease or condition comprising,
(a) labeling the miRNA isolated from a sample from a subject having or suspected of having a disease or condition; -
(b) hybridizing the miRNA to an miRNA array;
(c) determining miRNA hybridization to the array; and
(d) identifying miRNA differentially expressed in a sample representative of the disease or condition compared to a reference. - View Dependent Claims (149, 150, 151, 152, 153, 154, 155, 156, 157, 158, 159, 160, 161, 162, 163, 164, 165, 166, 167, 168, 169, 170, 171, 172, 173, 174, 175, 176, 177, 178, 179, 180)
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Specification