INTRAOCULAR PRESSURE ATTENUATION DEVICE
First Claim
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1. An attenuation device, comprising:
- a flexible housing comprising an outer wall and defining a chamber therein, wherein the chamber having an expanded volume within a range from about 0.01 cc to about 7 cc and being positionable within a patient'"'"'s eye; and
at least one high vapor pressure media having a vapor pressure approximately equal to an intraocular pressure of the patient'"'"'s eye and a permeability of less than 1 ml/day at body temperature through the outer wall.
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Abstract
Described herein are devices and methods that dampen transient intraocular pressure including pressure spikes experienced by the eye. The illustrative embodiments attenuate pressure waves and, thus, reduce wall stresses in a non-compliant eye such that the optic nerve is protected from damage in an ocular hypertensive or glaucoma patient, or during traumatic ocular procedures, and the refractive disorders of myopia, hyperopia, and/or presbyopia are moderated or reversed. In one embodiment, a compressible attenuation device insertable within the chambers of the eye preferably has an expanded volume within the range of from about 0.01 cc to 7 cc. The attenuation device may include a valve for permitting filling of the attenuation device through a delivery system. In another embodiment, the attenuation device comprises a flexible housing and a high vapor pressure media having a vapor pressure approximately equal to the intraocular pressure of the eye and a permeability of less than 1 ml/day at body temperature through an outer wall of the flexible housing.
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Citations
108 Claims
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1. An attenuation device, comprising:
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a flexible housing comprising an outer wall and defining a chamber therein, wherein the chamber having an expanded volume within a range from about 0.01 cc to about 7 cc and being positionable within a patient'"'"'s eye; and
at least one high vapor pressure media having a vapor pressure approximately equal to an intraocular pressure of the patient'"'"'s eye and a permeability of less than 1 ml/day at body temperature through the outer wall. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21)
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22. A method of treating a patient, comprising the steps of:
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introducing a compressible attenuation device which is moveable from a first, introduction configuration to a second, implanted configuration, into the eye while in the first configuration;
transforming the attenuation device within the eye to the second configuration, wherein the second configuration having a volume within a range from about 0.01 cc to about 7 cc; and
attenuating a pressure change within the eye by reversibly changing the volume of the attenuation device in response to the pressure change. - View Dependent Claims (23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60)
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61. A method of treating a patient with retinal detachment, comprising the steps of advancing a compressible device into the patient'"'"'s eye and attenuating a pressure change within the eye by reversibly changing the volume of the compressible device in response to the pressure change.
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62. A method of protecting a patient'"'"'s ocular tissues from temporary or transient pressure spikes during ocular procedures, comprising the steps of
introducing a compressible device into a eye prior to conducting an ocular procedure, performing the ocular procedure, and attenuating a pressure change within the eye during the ocular procedure by reversibly changing the volume of the compressible device in response to the pressure change.
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63. A method of improving the symptoms of glaucoma in a patient, comprising the steps of
positioning a compressible device within a chamber of the patient'"'"'s eye, and inhibiting a decrease in compliance of the eye.
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65. A compressible attenuator device for treating symptoms of glaucoma, comprising a compressible chamber having an expanded volume within the range of from about 0.01 cc to about 7 cc, and a valve for permitting filling of the chamber through a filling device;
- wherein the valve has a first pair of complementary surfaces for resisting deflation of the chamber, and a second pair of complementary surfaces for resisting additional filling of the chamber when the chamber is exposed to an external pressure which is greater than an internal pressure within the attenuator.
- View Dependent Claims (66, 67, 68, 69, 70)
- 71. A device for attenuating pressure increases in a patient'"'"'s eye comprising a body having a compressible region extending from an optically clear region, wherein the body is positionable within a chamber of the eye with the optically clear region crossing the optical axis of the eye.
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92. A method of improving the compliance of the structures of a patient'"'"'s eye, comprising the steps of
inserting a pressure attenuation device within a chamber of the patient'"'"'s eye, and unloading the mechanical stress and strain in the structures of the eye.
Specification
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Current AssigneeAttenuex Technologies, Inc.
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Original AssigneeAttenuex Technologies, Inc.
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InventorsCunanan, Crystal, Pardo, Geoffrey, Connors, Kevin
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Application NumberUS11/737,054Publication NumberTime in Patent OfficeDaysField of SearchUS Class Current600/399CPC Class CodesA61F 2/16 Intraocular lensesA61F 2/1616 Pseudo-accommodative, e.g. ...A61F 9/00781 Apparatus for modifying int...
