MICROFLUIDIC LARGE SCALE INTEGRATION
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Abstract
High-density microfluidic chips contain plumbing networks with thousands of micromechanical valves and hundreds of individually addressable chambers. These fluidic devices are analogous to electronic integrated circuits fabricated using large scale integration (LSI). A component of these networks is the fluidic multiplexor, which is a combinatorial array of binary valve patterns that exponentially increases the processing power of a network by allowing complex fluid manipulations with a minimal number of inputs. These integrated microfluidic networks can be used to construct a variety of highly complex microfluidic devices, for example the microfluidic analog of a comparator array, and a microfluidic memory storage device resembling electronic random access memories.
88 Citations
30 Claims
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1-22. -22. (canceled)
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23. A microfabricated structure comprising:
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an array of storage locations defined by a first plurality of parallel flow channels orthogonal to a second plurality of parallel flow channels; a network of control lines adjacent to the storage locations to define deflectable valves for isolating the storage locations; a first multiplexor structure configured to govern flow through the first plurality of parallel flow channels; and a second multiplexor structure configured to govern flow through the second plurality of parallel flow channels. - View Dependent Claims (24, 25, 26, 27, 28, 29)
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30-53. -53. (canceled)
Specification