ELECTRODE CONFIGURATIONS FOR REDUCING INVASIVENESS AND/OR ENHANCING NEURAL STIMULATION EFFICACY, AND ASSOCIATED METHODS

• US 20080033503A1
• Filed: 08/24/2007
• Published: 02/07/2008
• Est. Priority Date: 11/12/2004
• Status: Abandoned Application

• Current Assignee: Advanced Neuromodulation Systems Incorporated (Abbott Laboratories)
• Original Assignee: Northstar Neuroscience, Inc.
• Inventors: Gliner, Bradford, Fowler, Brad
• Application Number:
  US11/845,005
• Publication Number:
  US 20080033503A1
• Time in Patent Office: Days
• US Class Current: 607/45
• CPC Class Codes: A61N 1/0529 Electrodes for brain stimulation
• CPC Class Codes: A61N 1/0531 Brain cortex electrodes
• CPC Class Codes: A61N 1/36017 with leads or electrodes penetrating the skin
• CPC Class Codes: A61N 1/36082 Cognitive or psychiatric applications, e.g. dementia or Alzheimer's disease

Abstract

Electrode configurations for reducing invasiveness and/or enhancing neural stimulation efficacy, and associated methods, are disclosed. A method in accordance with one embodiment of the invention for treating a brain disorder includes identifying a target neural structure within a patient'"'"'s skull and implanting an electrode device within the patient'"'"'s skull so that an axis that is generally normal to the skull proximate to the electrode device and that passes through at least one electrical contact of the electrode device is offset from the target neural structure. The method further includes stimulating the target neural structure by applying an electrical signal to the at least one electrical contact. In particular embodiments, the electrode device can be positioned between, along, across, or adjacent to a fissure, recess, groove, and/or vascular structure of the patient'"'"'s brain.

Claims

1-60. -60. (canceled)

61. A method for treating a brain disorder, comprising:

implanting at least one electrode device within a patient'"'"'s skull so that at least one electrical contact of the electrode device is positioned at least proximate to a neuronal cell that is elongated generally along an axis that is generally not perpendicular to the skull proximate to the neuronal cell; and

applying an electrical signal to the at least one electrical contact along electrical field lines that are generally aligned with the axis.

62. The method of claim 61 wherein applying an electrical signal includes applying an electrical signal along electrical field lines that are generally parallel to the skull proximate to the neuronal cell.

63. The method of claim 61 wherein implanting at least one electrode device includes implanting a first electrode device having a first electrical contact and implanting a second electrode device having a second electrical contact spaced apart from the first electrical contact, and wherein applying an electrical signal includes directing an electrical signal from the first electrode to the second electrode, generally parallel to the axis.

64. The method of claim 61 wherein implanting the electrode device includes implanting the electrode device at one from the group of an epidural and a subdural location.

65. The method of claim 61 wherein applying an electrical signal includes applying a unipolar signal.

66. The method of claim 61 wherein applying an electrical signal includes applying a bipolar signal.

67. The method of claim 61 wherein implanting the electrode device includes positioning a first electrical contact adjacent to and on one side of a cranial vascular structure, and positioning a second electrical contact adjacent to and on an opposite side of the cranial vascular structure.

68. The method of claim 61 wherein implanting the electrode device includes positioning the at least one electrical contact proximate to the Sylvian fissure.

69. The method of claim 61 wherein applying an electrical signal includes alternating between a bipolar and a unipolar electrical signal.

70. The method of claim 61, further comprising varying at least one parameter according to which the electrical signal is applied while the electrode device is implanted beneath the patient'"'"'s skull.

71. The method of claim 61 wherein applying an electrical signal includes transferring the electrical signal from a first conductive structure located external to the patient'"'"'s scalp, via the patient'"'"'s scalp to a second conductive structure located beneath the patient'"'"'s scalp.

72. The method of claim 61 wherein implanting an electrode assembly includes implanting multiple electrode assemblies and wherein the method further comprises coupling the multiple electrode assemblies to a single pulse generator.

73-81. -81. (canceled)