Implantable Medical Device with Particulate Coating
First Claim
Patent Images
1. A method of securing a medical device within a body vessel, the method comprising:
- (a) inserting a wire guide into a body vessel and advancing the wire guide to a point of treatment;
(b) inserting a medical device delivery system into the body vessel along the wire guide, the medical device delivery system including a delivery catheter and a radially-expandable medical device releasably contacting a distal portion of the delivery catheter, the medical device being in a radially compressed configuration and having a vessel-engaging surface consisting of a plurality of inorganic particles adhered to a surface of the medical device to form the vessel-engaging surface with an average surface roughness of between about 10 nm and 100 micrometers and having a hardness of about 30-80 HRD on the “
D”
scale measured by the ASTM D2240 type D standard;
(c) advancing the distal portion of the delivery catheter with the medical device within the body vessel to the point of treatment within the body vessel;
(d) radially expanding the medical device at the point of treatment to directly contact the vessel-engaging surface with an inner wall of the body vessel;
(e) engaging the vessel-engaging surface with inner wall of the body vessel by embedding at least a portion of the vessel-engaging surface within the inner wall of the body vessel to secure the medical device within the body vessel;
(f) releasing the delivery catheter from the medical device; and
(g) removing the delivery catheter and the wire guide from the body vessel while retaining the medical device at the point of treatment within the body vessel.
1 Assignment
0 Petitions
Accused Products
Abstract
Medical devices for implantation in a body vessel, and methods of using and making the same, are provided. A medical device can include a frame with a vessel-engaging region on at least a portion of the medical device. The vessel-engaging region may be a particulate coating configured and adapted to engage the interior wall of a body vessel or to attach a material, such as a valve leaflet or graft material, to the frame. Methods of making an implantable medical device and methods of treating a subject are also disclosed.
-
Citations
20 Claims
-
1. A method of securing a medical device within a body vessel, the method comprising:
-
(a) inserting a wire guide into a body vessel and advancing the wire guide to a point of treatment; (b) inserting a medical device delivery system into the body vessel along the wire guide, the medical device delivery system including a delivery catheter and a radially-expandable medical device releasably contacting a distal portion of the delivery catheter, the medical device being in a radially compressed configuration and having a vessel-engaging surface consisting of a plurality of inorganic particles adhered to a surface of the medical device to form the vessel-engaging surface with an average surface roughness of between about 10 nm and 100 micrometers and having a hardness of about 30-80 HRD on the “
D”
scale measured by the ASTM D2240 type D standard;(c) advancing the distal portion of the delivery catheter with the medical device within the body vessel to the point of treatment within the body vessel; (d) radially expanding the medical device at the point of treatment to directly contact the vessel-engaging surface with an inner wall of the body vessel; (e) engaging the vessel-engaging surface with inner wall of the body vessel by embedding at least a portion of the vessel-engaging surface within the inner wall of the body vessel to secure the medical device within the body vessel; (f) releasing the delivery catheter from the medical device; and (g) removing the delivery catheter and the wire guide from the body vessel while retaining the medical device at the point of treatment within the body vessel. - View Dependent Claims (2, 3, 4)
-
-
5. A method of securing a medical device having a vessel-engaging surface within a body vessel, the method comprising:
-
(a) inserting a radially-expandable medical device into a body vessel in a radially compressed configuration, the medical device including a vessel-engaging surface having a plurality of inorganic particles adhered to the medical device with an average surface roughness of between about 10 nm and 100 micrometers and having a hardness of between about 30-100 HRD on the “
D”
scale measured by the ASTM D2240 type D standard;(b) advancing the medical device within the body vessel to a point of treatment within the body vessel; (c) radially expanding the medical device to directly contact the vessel-engaging surface with an inner wall of the body vessel; and (d) engaging the vessel-engaging surface with inner wall of the body vessel by embedding at least a portion of the vessel-engaging surface within the inner wall of the body vessel to secure the medical device within the body vessel. - View Dependent Claims (6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16)
-
-
17. A medical device comprising a radially expandable frame adapted for implantation in a body vessel, the frame defining a substantially tubular lumen and having an exterior surface, wherein at least a portion of the exterior surface comprises a vessel-engaging surface formed by a plurality of particles attached to the exterior surface to form the vessel-engaging surface with an average roughness of about 10 nm and 100 μ
- m having a hardness of between about 30-100 HRD on the “
D”
scale measured by the ASTM D2240 type D standard, and the plurality of particles consisting of one or more materials selected from the group consisting of;
metals, inorganic oxides and cellulose-containing biomaterials. - View Dependent Claims (18, 19, 20)
- m having a hardness of between about 30-100 HRD on the “
Specification