Electroprocessed Collagen and Tissue Engineering
2 Assignments
0 Petitions
Accused Products
Abstract
The invention is directed to formation and use of electroprocessed collagen, including use as an extracellular matrix and, together with cells, its use in forming engineered tissue. The engineered tissue can include the synthetic manufacture of specific organs or tissues which may be implanted into a recipient. The electroprocessed collagen may also be combined with other molecules in order to deliver substances to the site of application or implantation of the electroprocessed collagen. The collagen or collagen/cell suspension is electrodeposited onto a substrate to form tissues and organs.
-
Citations
79 Claims
-
1-17. -17. (canceled)
- 18. An engineered mat-like matrix, comprising electrospun isolated collagen fibers, wherein the electrospun isolated collagen fibers are cross-linked.
- 33. An engineered mat-like matrix, comprising cross-linked electroaerosolized collagen droplets.
- 49. An engineered mat-like matrix, comprising electrospun isolated collagen fibers, wherein the electrospun isolated collagen fibers are chemically cross-linked.
- 64. An engineered mat-like matrix, comprising electrospun isolated collagen fibers, wherein the electrospun isolated collagen fibers are cross-linked, and wherein the matrix induces differentiation of cells in vivo or in vitro.
Specification