METHOD OF MEDICAL TREATMENT USING CONTROLLED HEAT DELIVERY

• US 20080039769A1
• Filed: 11/21/2006
• Published: 02/14/2008
• Est. Priority Date: 11/07/2001
• Status: Abandoned Application

• Current Assignee: Minu, LLC
• Original Assignee: Minu, LLC
• Inventors: Peyman, Gholam A.
• Application Number:
  US11/562,268
• Publication Number:
  US 20080039769A1
• Time in Patent Office: Days
• US Class Current: 604/20
• CPC Class Codes: A61F 2007/0004 Eyes or part of the face surrounding the eyes
• CPC Class Codes: A61F 2007/0071 using a resistor, e.g. near the spot to be heated
• CPC Class Codes: A61F 2007/0086 with a thermostat
• CPC Class Codes: A61F 2009/00853 Laser thermal keratoplasty or radial keratotomy
• CPC Class Codes: A61F 2009/00872 Cornea
• CPC Class Codes: A61F 2009/0088 based on wavefront
• CPC Class Codes: A61F 7/02 Compresses or poultices for effecting heating or cooling
• CPC Class Codes: A61F 9/008 using laser
• CPC Class Codes: A61F 9/00827 Refractive correction, e.g. lenticle
• CPC Class Codes: A61F 9/00834 Inlays; Onlays; Intraocular lenses [IOL]
• CPC Class Codes: A61F 9/009 Auxiliary devices making contact with the eyeball and coupling in laser light, e.g. goniolenses apparatus for eye examination A61B3/0008

Abstract

The present invention relates to a system for treating a patient. The system includes a device configured to be positioned adjacent a portion of the patient, a medicinal substance delivery device, adapted to delivery a medicinal substance to the portion of the patient, a heating means adapted to provide heat to the device and a control system configured to monitor the heating means and control the temperature of the device at the portion of the patient.

Claims

1. A system for treating a patient, comprising:

a device configured to be positioned adjacent a portion of the patient;

a medicinal substance delivery device, adapted to delivery a medicinal substance to the portion of the patient;

a heating means adapted to provide heat to said device; and

a control system configured to monitor said heating means and control the temperature of said device at the portion of the patient.

2. A system according to claim 1, wherein

said control system is a computer control system.

3. A system according to claim 1, wherein

said device is configured to be positioned on a portion of a patient selected from the group consisting of;

the cornea, the sclera and the skin.

4. A system according to claim 1, wherein

said device is configured to be positioned between layers of the cornea.

5. A system according to claim 4, wherein

said device is substantially circular.

6. A system according to claim 1, wherein

said control system is configured to control the temperature of the device, such that the portion of the patient is heated to between about 25 degrees Celsius and about 35 degrees Celsius.

7. A system according to claim 1, wherein

said device is configured to alter the refractive properties of the eye.

8. A system according to claim 1, wherein

said medicinal substance is a substance selected from the group consisting of antibiotics, anti-fungals, antivirals, anti-cancers, anti-inflammatories, anti-prostaglandins, steroids, hormones, growth factors, NGF, GGF, enzymes, Anti-VEGF, Anti-PDGF, VEGF, Anti-glaucoma, siRNA, nano particles, Antibodies, macrolides, hydrophilic compounds and lipophilic compounds.

9. A system according to claim 1, wherein

said heating means is selected from the group consisting of radiation, light, ultrasound, or electrical current.

10. A method of treating a patient, comprising the steps of

positioning a device adjacent a portion of a patient,

delivering a medicinal substance to said portion of the patient,

heating the device,

monitoring the temperature at said portion of the patient, and

controlling the temperature of the device.

11. A method according to claim 10, wherein

said step of controlling the temperature includes controlling the temperature using a computer control system.

12. A method according to claim 10, wherein

said heating step includes heating a device configured to be positioned on the surface of the cornea.

13. A method according to claim 12, wherein

said positioning step includes positioning a device that is substantially circular.

14. A method according to claim 10, wherein

said controlling step includes controlling the temperature of the device, such that the portion of the patient is heated to between about 25 degrees Celsius and about 35 degrees Celsius.

15. A method according to claim 10, wherein

said delivering step includes delivering a medicinal substance selected from the group consisting of antibiotics, anti-fungals, antivirals, anti-cancers, anti-inflammatories, anti-prostaglandins, steroids, hormones, growth factors, NGF, GGF, enzymes, Anti-VEGF, Anti-PDGF, VEGF, Anti-glaucoma, siRNA, nano particles, Antibodies, macrolides, hydrophilic compounds and lipophilic compounds.

16. A method according to claim 10, wherein

said heating step includes heating the device using at least one of the following:

radiation, light, ultrasound, or electrical current.

17. A system for treating a patient, comprising:

a device configured to be implanted in a portion of an animal;

a heating means for heating the device to an appropriate temperature; and

a control system configured to monitor said heating means and control the temperature of said device at the portion of the patient.

18. A system according to claim 17, wherein

said heating means to coupled to said device and implanted in the portion of the animal;

and

said control system includes an external remote device configured to send a signal to said heating means.

19. A system according to claim 17, wherein

said heating means is external to said animal;

and

said control system is adapted to control said heating means such that said heating means transfers heat to said device.

20. A system according to claim 19, wherein

said heating means is a device selected from the group consisting laser or radiation.

21. A system according to claim 17, further comprising

a drug delivery system.

22. A system according to claim 21, wherein

said drug delivery system is selected from the group consisting of drops, ointment, microspheres, nano-particles, compacted nano-particles and viral factor.

23. A method for treating a patient, comprising the steps of

implanting a device in a portion of an animal,

heating the device to an appropriate temperature,

monitoring the temperature of the device, and

controlling the temperature of said device at the portion of the patient.

24. A method according to claim 23, further comprising the step of

administering a drug at said portion of the animal.