Trans-Septal Left Ventricular Pressure Measurement

• US 20080039897A1
• Filed: 08/09/2007
• Published: 02/14/2008
• Est. Priority Date: 08/10/2006
• Status: Abandoned Application

• Current Assignee: Data Sciences U K Limited (International Business Machines Corporation)
• Original Assignee: Data Sciences U K Limited (International Business Machines Corporation)
• Inventors: Kluge, Stanley E., Rudie, Eric N., Mazar, Scott Thomas, Zwiers, Lynn M.
• Application Number:
  US11/836,592
• Publication Number:
  US 20080039897A1
• Time in Patent Office: Days
• US Class Current: 607/17
• CPC Class Codes: A61B 5/0215 by means inserted into the body catheters A61M25/00
• CPC Class Codes: A61N 1/057 Anchoring means; Means for fixing the head inside the heart
• CPC Class Codes: A61N 1/3627 for treating a mechanical deficiency of the heart, e.g. congestive heart failure or cardiomyopathy
• CPC Class Codes: A61N 1/36564 controlled by blood pressure

Abstract

A pressure sensing device includes a body portion, a pressure transmitting port, and an electrical lead. The body portion includes transducing electronics within a housing that is shaped about a longitudinal axis. The housing has a coating thereon that promotes tissue growth to anchor the housing within a ventricular septum. The pressure transmitting port is located at a distal longitudinal end of the body portion such that a ventricle pressure being sensed is transmitted through the port and to the transducing electronics when the body portion is anchored in the ventricular septum. The electrical lead is connected to the transducing electronics and exits from a proximal longitudinal end of the body portion.

Claims

1. A pressure sensing device comprising:

a body portion having transducing electronics within a housing that is shaped about a longitudinal axis, the housing having a coating thereon that promotes tissue growth to anchor the housing within a ventricular septum;

a pressure transmitting port located at a distal longitudinal end of the body portion such that a ventricle pressure being sensed is transmitted through the port and to the transducing electronics when the body portion is anchored in the ventricular septum; and

an electrical lead connected to the transducing electronics and exiting from a proximal longitudinal end of the body portion.

2. The pressure measurement device of claim 1, wherein the coating comprises pores.

3. The pressure measurement device of claim 2, wherein the coating promotes tissue ingrowth of the ventricular septum into the pores to anchor the body portion in the ventricular septum.

4. The pressure measurement device of claim 1, wherein the coating comprises expanded polytetrafluoroethylene.

5. The pressure measurement device of claim 1, wherein the coating comprises polyethylene terephthalate.

6. A method of measuring pressure in a left ventricle, the method comprising:

inserting a pressure sensing device through a ventricular septum to sense a pressure in a left ventricle, the pressure sensing device including;

(a) a body portion having transducing electronics within a housing that is shaped about a longitudinal axis, the housing having a coating thereon that promotes tissue growth to anchor the housing within the ventricular septum,

(b) a pressure transmitting port located at a distal longitudinal end of the body portion such that a ventricle pressure being sensed is transmitted through the port and to the transducing electronics when the body portion is anchored in the ventricular septum, and

(c) an electrical lead connected to the transducing electronics and exiting from a proximal longitudinal end of the body portion;

wherein inserting the pressure sensing device includes positioning the body portion in the ventricular septum and the port in the left ventricle.

7. The method of claim 6, wherein the coating comprises pores.

8. The method of claim 7, wherein the coating promotes tissue ingrowth of the ventricular septum into the pores to anchor the body portion in the ventricular septum.

9. The method of claim 6, wherein the coating comprises expanded polytetrafluoroethylene.

10. The method of claim 6, wherein the coating comprises polyethylene terephthalate.

11. The method of claim 6, wherein the body portion is anchored in the ventricular septum by frictional engagement between the coating and the ventricular septum.

12. The method of claim 6, further comprising forming a passage in the ventricular septum, wherein inserting the pressure sensing device includes passing the passing the pressure sensing device through the passage.

13. The method of claim 12, wherein the passage has a first diameter and the housing has a second diameter greater than the first diameter, wherein inserting the body portion in the ventricular septum results in the final dilatation of the passage.

14. The method of claim 6, further comprising:

inserting an introducing apparatus into a vein, the introducing apparatus including an introducer, a sheath disposed at least partially in the introducer, a centering tube disposed at least partially in the sheath, and a needle disposed at least partially in the centering tube, wherein the centering tube centers the needle with respect to the sheath;

advancing the introducing apparatus to a right ventricle;

placing a distal end of the introducing apparatus against the ventricular septum;

extending the needle through the ventricular septum into a left ventricle for initial registration;

extending the sheath partially into the ventricular septum for registration;

removing the needle and the centering tube and leaving the sheath in place to maintain registration;

passing the pressure sensing device through an interior of the sheath to insert the pressure sensing device through the ventricular septum; and

removing the sheath and the introducer without dislodging the pressure sensing device.

15. The method of claim 14, further comprising using a pressure measurement at the distal tip of the introducing apparatus to determine a location of the distal tip of the introducing apparatus while advancing the introducing apparatus to the right ventricle based on pressure changes from one location to another location while advancing the introducing apparatus to the right ventricle.

16. The method of claim 15, further comprising using fluoroscopy to determine a location of the distal tip of the introducing apparatus while advancing the introducing apparatus to the right ventricle.

17. The method of claim 14, further comprising:

confirming a location of a distal tip of the needle while extending the needle through the ventricular septum into the left ventricle for initial registration; and

confirming a location of the pressure sensing device while inserting the pressure sensing device through the interior of the sheath into the ventricular septum.

18. The method of claim 14, wherein the needle is a modified Brockenbrough needle.

19. The method of claim 14, wherein the introducing apparatus is assembled prior to being inserted into the vein, so that a distal end of the sheath protrudes slightly through a flared distal end of the introducer, and a distal end of the needle extends through a distal end of the centering tube and the distal end of the sheath.

20. The method of claim 14, wherein the centering tube has an outer diameter substantially equal to an outer diameter of the pressure measurement device and an inner diameter substantially equal to an outer diameter of the needle.