DEVICES FOR REDUCING THE SIZE OF AN INTERNAL TISSUE OPENING

• US 20080039952A1
• Filed: 08/08/2007
• Published: 02/14/2008
• Est. Priority Date: 08/09/2006
• Status: Active Grant

• Current Assignee: Coherex Medical, Inc. (Johnson & Johnson)
• Original Assignee: Coherex Medical, Inc. (Johnson & Johnson)
• Inventors: Davis, Clark, Fox, DeWayne, Linder, Richard, Miles, Scott, Edmiston, Daryl
• Granted Patent: US 9,138,208 B2
• Time in Patent Office: Days
• US Class Current: 623/23.75
• CPC Class Codes: A61B 17/0057 Implements for plugging an opening in the wall of a hollow or tubular organ, e.g. for sealing a vessel puncture or closing a cardiac septal defect sutures A61B17/04; closing rectum or urethra near body surface A61F2/0009
• CPC Class Codes: A61B 17/0487 Suture clamps, clips or locks, e.g. for replacing suture knots; Instruments for applying or removing suture clamps, clips or locks suture anchors A61B17/0401; wound clamps or clips A61B17/08; ligaturing clamps or clips A61B17/122
• CPC Class Codes: A61B 17/083 Clips, e.g. resilient
• CPC Class Codes: A61B 17/12122 within the heart for closing a cardiac septal defect A61B17/0057
• CPC Class Codes: A61B 17/12168 having a mesh structure A61B17/1214 takes precedence
• CPC Class Codes: A61B 17/12172 having a pre-set deployed three-dimensional shape methods of manufacturing A61B2017/00526
• CPC Class Codes: A61B 2017/00084 Temperature
• CPC Class Codes: A61B 2017/00407 Ratchet means
• CPC Class Codes: A61B 2017/00575 for closure at remote site, e.g. closing atrial septum defects
• CPC Class Codes: A61B 2017/00579 Barbed implements
• CPC Class Codes: A61B 2017/00588 Rigid or stiff implements, e.g. made of several rigid parts linked by hinges
• CPC Class Codes: A61B 2017/00592 Elastic or resilient implements
• CPC Class Codes: A61B 2017/00597 Implements comprising a membrane
• CPC Class Codes: A61B 2017/00601 Implements entirely comprised between the two sides of the opening
• CPC Class Codes: A61B 2017/00606 Implements H-shaped in cross-section, i.e. with occluders on both sides of the opening
• CPC Class Codes: A61B 2017/0061 Implements located only on one side of the opening
• CPC Class Codes: A61B 2017/00619 Locking means for locking the implement in expanded state
• CPC Class Codes: A61B 2017/00623 Introducing or retrieving devices therefor
• CPC Class Codes: A61B 2017/00654 entirely comprised between the two sides of the opening
• CPC Class Codes: A61B 2017/00858 high friction or non-slip
• CPC Class Codes: A61B 2017/00862 : elastic or resilient
• CPC Class Codes: A61B 2017/00867 : shape memory effect
• CPC Class Codes: A61B 2017/00884 : enhancing wound closure
• CPC Class Codes: A61B 2017/0488 : Instruments for applying suture clamps, clips or locks
• CPC Class Codes: A61B 2017/0496 : for tensioning sutures
• CPC Class Codes: A61B 2017/12054 : Details concerning the detachment of the occluding device from the introduction device

Abstract

A medical system for treating an internal tissue opening can include a closure device and associated delivery device. The closure device can include a body portion operatively associated with a first anchor and a second anchor. The body portion can include a plurality of segments defining a multi-cellular structure. The closure device can be configured to apply lateral force to tissue of the internal tissue opening to bring tissue together. The closure device can have a substantially flat aspect, and have a depth thickness that is substantially greater than the thickness or width of a majority of the members forming the closure device to reduce out of plane bending. The closure device can also include a member adapted to induce tissue growth.

Claims

1. An expandable medical device deployable at least partially within a tissue structure, the expandable medical device comprising:

a non-tubular multi-cellular body portion configured to self expand from a non-deployed orientation, said body portion comprising a plurality of interconnecting body support segments defining at least two apertures; and

at least one anchor linked to said multi-cellular body portion.

2. A medical device as recited in claim 1, wherein said body portion is configured to assume a substantially flat configuration.

3. A medical device as recited in claim 1, wherein said body portion comprises three or more cells.

4. A medical device as recited in claim 1, wherein said body portion is configured to apply lateral force to tissue of the tissue structure.

5. A medical device as recited in claim 1, wherein at least one of said body support segments has a width that varies along at least a portion of the length of said at least one body support segment.

6. A medical device as recited in claim 1, further comprising at least a second anchor operatively associated with said body portion.

7. A medical device as recited in claim 1, further comprising a member operatively associated with said body portion, wherein said member is configured to induce tissue growth.

8. An expandable medical device deployable at least partially within a tissue structure, the expandable medical device comprising:

a frame configured to assume a substantially flat configuration, said frame comprising a central portion adapted to move between a first orientation and a second orientation, said central portion comprising a plurality of struts defining a multi-cellular structure.

9. A medical device as recited in claim 8, wherein said frame comprises a superelastic material.

10. A medical device as recited in claim 8, wherein said frame is configured to assume said substantially flat configuration lying in a first plane, said frame being configured to resist movement out of said first plane of the substantially flat configuration.

11. A medical device as recited in claim 8, wherein said central portion is configured to preferentially expand to said second orientation.

12. A medical device as recited in claim 8, further comprising a first anchor operatively associated with a distal portion of said central portion.

13. A medical device as recited in claim 12, wherein said first anchor is configured to reduce proximal movement of the medical device when the medical device is positioned in the tissue structure.

14. A medical device for reducing a size of a Patent Foramen Ovale (“

PFO”

), the medical device comprising;

a self-expanding frame configured to be constricted within a catheter and configured to assume a substantially flat configuration, said frame comprising a central portion with proximal and distal anchors extending from said central portion, said central portion comprising a multi-cellular structure configured to self-expand outwardly against a wall of the PFO.

15. A medical device as recited in claim 14, wherein said frame comprises a flat stent.

16. A medical device as recited in claim 14, wherein said proximal anchor is linked to said central portion.

17. A medical device as recited in claim 14, wherein said proximal anchor is adapted to engage at least a portion of a tunnel of the PFO and the right atrial wall of a heart.

18. A medical device as recited in claim 17, wherein said distal anchor is adapted to engage at least a portion the tunnel of the PFO.

19. A medical device as recited in claim 14, wherein at least one of said proximal or distal anchors comprises one or more engaging members.

20. A medical device for reducing the size of an internal tissue opening, the medical device comprising:

a frame including a central portion having a plurality of struts defining a multi-cellular structure, said central portion having at least one anchor extending from said central portion, said central portion configured to assume a substantially flat configuration; and

a member associated with said frame, said member adapted to induce tissue growth in the internal tissue opening.

21. A medical device as recited in claim 20, wherein said central portion is configured to preferentially expand.

22. A medical device as recited in claim 20, wherein said member comprises an ingrowth member.

23. A medical device as recited in claim 20, wherein said member is secured to said central portion by a securement member.

24. A medical device as recited in claim 20, wherein said member is associated with said frame through an adhesive.

25. A medical device as recited in claim 20, wherein said member is configured to substantially extend out from said central portion.

26. A medical device as recited in claim 20, wherein said member comprises at least one of polylactide or polyglycolide or collagen.

27. A medical device as recited in claim 20, wherein said member comprises a bio-resorbable material.

28. A medical device for closing an internal tissue opening, the medical device comprising:

a frame including a central portion with at least one anchor extending from said central portion, said central portion configured to assume a substantially flat configuration; and

a tissue growth promoting member attached to said frame, said tissue growth promoting member configured to substantially extend out-of-plane from the substantially flat configuration and configured to enhance tissue growth in the internal tissue opening.

29. A medical device as recited in claim 28, wherein said frame comprises a flat stent.

30. A medical device as recited in claim 28, wherein said central portion comprises two or more cells.

31. A medical device as recited in claim 28, wherein said central portion comprises a plurality of support segments defining a multi-cellular structure.

32. A medical device as recited in claim 28, wherein said tissue growth promoting member comprises an ingrowth material.

33. A medical device as recited in claim 28, wherein said tissue growth promoting member is secured to said frame by a securing means.

34. A medical device as recited in claim 33, wherein said securing means includes at least one of a securement member or an adhesive.

35. A medical device as recited in claim 28, wherein said tissue growth promoting member comprises a bio-resorbable material.