One part, solids containing decontamination blend composition

• US 20080045593A1
• Filed: 08/15/2006
• Published: 02/21/2008
• Est. Priority Date: 08/15/2006
• Status: Active Grant

• Current Assignee: Government of the United States of America, American Sterilizer Company (Steris Corporation), United States Secretary of the Army
• Original Assignee: Steris Inc (Steris Corporation)
• Inventors: Tienes, Bryan M., Thanavaro, Anchalee, Dell'Aringa, Brandon W., Wagner, George W., Klein, Daniel A., Kaiser, Herbert J.
• Granted Patent: US 9,724,550 B2
• Time in Patent Office: Days
• US Class Current: 514/557
• CPC Class Codes: A61L 2/186 Peroxide solutions
• CPC Class Codes: A61L 2/23 Solid substances, e.g. granules, powders, blocks, tablets
• CPC Class Codes: A61L 2202/24 Medical instruments, e.g. endoscopes, catheters, sharps
• CPC Class Codes: A62D 2101/02 Chemical warfare substances, e.g. cholinesterase inhibitors
• CPC Class Codes: A62D 3/38 by oxidation; by combustion

Abstract

A one part, solids containing decontamination blend composition comprises a solid acetyl donor coated with a compound that protects it from hydrolysis, a peroxygen source, optionally a catalyst, optionally a surfactant, and optionally a buffer. The decontamination blend composition is generally in a dry powder, particle, etc. form or in a tablet, pill, etc. form and is complete in and of itself in that no additional compounds are required prior to use and is readily distributed as a one package system. Upon the addition of water, a peroxygen compound such as hydrogen peroxide is formed, and peracetic acid is generated under alkaline conditions. The decontamination blend composition is particularly suitable for oxidizing various chemical and biological compounds thereby eradicating the same in situ as on surfaces, clothes, articles, and the like. Representative contaminants include mustard gas, nerve gas, bacterial toxins, anthrax, bird flu, and the like.

Claims

1. A decontamination composition for treating chemical or biological agents, comprising:

a one part, solids containing blend, comprising;

an acetyl donor coated with a hydrolysis resistant compound;

a peroxygen source;

an optional catalyst;

an optional surfactant, and

an optional buffer.

2. The decontamination composition according to claim 1,

wherein the amount of said acetyl donor is from about 10% to about 70% by weight;

wherein the amount of said peroxygen source is from about 10% to about 70% by weight;

wherein the amount of said coating compound is from about 1% to about 20% by weight, and

wherein said weight percentages are based upon the total weight of said acetyl donor, said coating compound, and said peroxygen source, said optional catalyst, said optional surfactant, and said optional buffer.

3. The decontamination composition according to claim 2,

wherein said acetyl donor is a source of peracetic acid,

wherein said coating compound comprises an organic acid comprising carboxylic and dicarboxylic acids;

a weak mineral acid;

a cellulosic compound;

a long chain soluble alcohol;

a fatty acid, or a fatty acid salt, or mixtures thereof;

a polymer;

a gelatin;

a maltodextrin;

a sugar;

or a latex;

or combinations thereof;

including at least one buffer, and including at least one surfactant, wherein the amount of said buffer is from about 5% to about 50% by weight and wherein the amount of said surfactant is from about 0.01% to about 10% by weight;

wherein said weight percentages are based upon the total weight of said acetyl donor, said coating material, said peroxygen source, said surfactant, said buffer, and said optional catalysts.

4. The decontamination composition according to claim 3,

wherein said acetyl donor comprises acetylsalicylic acid, acetic anhydride, tetraacetylethylenediamine, pentaacetyl glucose, acetylcholine, or acetyl borate derivatives, or combinations thereof;

wherein said peroxygen source is a percarbonate salt comprising sodium percarbonate or potassium percarbonate, a perborate salt comprising a sodium perborate or potassium perborate, a persulfate salt comprising sodium persulfate or potassium persulfate, calcium peroxide, magnesium peroxide, urea peroxide, potassium monopersulfate, or peroxydone, or combinations thereof;

wherein said coating compound comprises a carboxylic acid having from 1 to 20 carbon atoms, a dicarboxylic acid having from 2 to 8 carbon atoms, boric acid, hydroxy propyl methyl cellulose, hydroxylpropyl cellulose, hydroxyethyl cellulose, ethyl cellulose, acetyl cellulose, benzyl cellulose, cellulose acetobutylate, cellulose acetylphthalate, polyvinyl alcohol, polymethyl methacrylate copolymer, acrylic resin, lactic acid, glycolic acid oligomer, polyethylene glycol, polyvinyl pyrolidone, polycaprolactone, polyorthoester, or polyanhydride, or combinations thereof;

wherein the amount of said acetyl donor is from about 15% to about 55% by weight, wherein the amount of said coating compound is from about 1.25% to about 15% by weight, and wherein the amount of said peroxygen source is from about 15% to about 60% by weight.

5. The decontamination composition according to claim 4,

including at least one catalyst comprising a non-metal catalysts, a transition metal catalyst or a non-metal transition catalyst, wherein the amount of said catalyst is from about 0.1 to about 6% by weight based upon the total weight of said acetyl donor, said coating compound, said peroxygen source, said catalyst, said surfactant, and said buffer;

wherein said buffer is a salt of a carbonate, a salt of a bicarbonate, a borate, a weak organic acid having from 1 to about 20 carbon atoms, or a phosphate, or combinations thereof; and

wherein said surfactant is an anionic surfactant, a nonanionic surfactant, or a cationic surfactant.

6. The decontamination composition according to claim 5,

wherein said acetyl donor acetylsalicylic acid, tetraacetylethylenediamine, acetylcholine, or pentaacetyl glucose, or combinations thereof;

wherein said coating compound is citric acid, boric acid, or salicylic acid, or combinations thereof;

wherein said peroxygen source is sodium percarbonate, sodium perborate, urea peroxide, oxone, or peroxydone, or combinations thereof;

wherein said catalyst is a molybdate compound or a tungsten compound, and

wherein said buffer is potassium bicarbonate, potassium carbonate, borax, or puffed borax, or combinations thereof.

7. The decontamination composition according to claim 6,

wherein the amount of said acetyl donor is from about 20% to about 35% by weight, wherein the amount of said coating compound is from about 1.5% to about 10% by weight, and wherein the amount of said peroxygen source is from about 30% to about 45% by weight.

8. The decontamination composition according to claim 1, wherein said composition is a free flowing composition or an integral solid.

9. The decontamination composition according to claim 3, wherein said composition is a free flowing composition or an integral solid.

10. The decontamination composition according to claim 5, wherein said composition is a free flowing composition or an integral solid.

11. The decontamination composition according to claim 7, wherein said composition is a free flowing composition or an integral solid.

12. A decontamination solution comprising:

the decontamination composition of claim 1 diluted with water so that peracetic acid and a peroxygen compound is generated.

13. A decontamination solution comprising:

the decontamination composition of claim 3 diluted with water so that peracetic acid and a peroxygen compound is generated, wherein the concentration of said peracetic acid is from about 0.5% to about 15% by weight, and wherein the concentration of said peroxygen is from about 0.5% to about 15% by weight based upon the total weight of said decontamination composition and said water.

14. A decontamination solution comprising:

the decontamination composition of claim 5 diluted with water so that the peracetic acid and a peroxygen compound is generated, wherein the concentration of said peracetic acid is from about 0.5% to about 10% by weight, and wherein the concentration of said peroxygen is from about 0.5% to about 10% by weight based upon the total weight of said decontamination composition and said water.

15. A decontamination solution comprising:

the decontamination composition of claim 7 diluted with water so that peracetic acid and a peroxygen compound is generated, wherein the concentration of said peracetic acid is from about 1% to about 3% by weight, and wherein the concentration of said peroxygen is from about 1% to about 3% by weight based upon the total weight of said decontamination composition and said water.

16. The decontamination composition according to claim 1, said composition when reacted with water being capable of oxidizing chemical and/or biological agents comprising mustard gas, nerve gas, soman (1,2,2-trimethylpropyl methylphosphonofluoridic acid ester), a blister agent, thioanisole, a toxic industrial material, a toxic industrial chemical, anthrax, an endospore, a fungi, a bacterial, a protozoa, prion, a virus, ricin, T-2-mycotoxon, bird flu, C-difficile, polio, small pox, pneumonia, ricin, or T-2-nycotox, or combinations thereof.

17. The decontamination composition according to claim 3, said composition when reacted with water being capable of oxidizing chemical and/or biological agents comprising mustard gas, nerve gas, soman (1,2,2-trimethylpropyl methylphosphonofluoridic acid ester), a blister agent, thioanisole, a toxic industrial material, a toxic industrial chemical, anthrax, an endospore, a fungi, a bacterial, a protozoa, a prion, a virus, ricin, T-2-mycotoxon, bird flu, C-difficile, polio, small pox, pneumonia, ricin, or T-2-nycotox, or combinations thereof.

18. The decontamination composition according to claim 5, said composition when reacted with water being capable of oxidizing chemical and/or biological agents comprising mustard gas HD (bis(2-chloroethyl) sulfide;

nerve gas VX (S-[2-[bis-(1-methylethyl)aminolethyl o-ethyl-methyl phosphonothioic acid ester, soman (1,2,2-trimethylpropyl methylphosphonofluoridic acid ester, a blister agent, small pox, polio, pneumonia, anthrax, ricin, T-2-mycotoxin, toxin industrial materials, toxin industrial chemicals, bird flu, C-difficile, HIV, endospores comprising Geobacillus stearothermophilus, Bacillus subtilis, Bacillus subtilis globigii, Clostridium sporogenes, Bacillus cereus, and Bacillus circulans, fungi comprising Aspergillus niger, Candida albicans, Trichophyton mentagrophytes, and Wangiella dermatitis, mycrobacteria comprising Mycobacterium chelonae, Mycobacterium gordonae, Mycobacterium smegmatis, and Mycobacterium terrae, vegetative bacteria comprising Aeromonas hydrophila, Enterococcus faecalis, Streptococcus faecalis, Enterococcus faecium, Streptococcus pyrogenes, Escherichia coli, Klebsiella (pneumoniae), Legionella pneumophila, Methylobacterium, Pseudomonas aeruginosa, Salmonella choleraesuis, Helicobacter pylori, Staphylococus aureus, Staphylococcus epidermidis, and Stenotrophomonas maltophilia, protozoa comprising Giardia lamblia and Cryptosporidium parvum, or prions comprising infectious proteins, or combinations thereof.

19. The decontamination composition according to claim 7, said composition when reacted with water being capable of oxidizing chemical and/or biological agents comprising mustard gas HD (bis(2-chloroethyl) sulfide;

nerve gas VX (S-[2-[bis-(1-methylethyl)amino]ethyl] o-ethyl-methyl phosphonothioic acid ester, soman (1,2,2-trimethylpropyl methylphosphonofluoridic acid ester, a blister agent, small pox, polio, pneumonia, anthrax, ricin, T-2-mycotoxin, toxin industrial materials, toxin industrial chemicals, bird flu, C-difficile, HIV, endospores comprising Geobacillus stearothermophilus, Bacillus subtilis, Bacillus subtilis globigii, Clostridium sporogenes, Bacillus cereus, and Bacillus circulans, fungi comprising Aspergillus niger, Candida albicans, Trichophyton mentagrophytes, and Wangiella dermatitis, mycrobacteria comprising Mycobacterium chelonae, Mycobacterium gordonae, Mycobacterium smegmatis, and Mycobacterium terrae, vegetative bacteria comprising Aeromonas hydrophila, Enterococcus faecalis, Streptococcus faecalis, Enterococcus faecium, Streptococcus pyrogenes, Escherichia coli, Klebsiella (pneumoniae), Legionella pneumophila, Methylobacterium, Pseudomonas aeruginosa, Salmonella choleraesuis, Helicobacter pylori, Staphylococcus aureus, Staphylococcus epidermidis, and Stenotrophomonas maltophilia, protozoa comprising Giardia lamblia and Cryptosporidium parvum, or prions comprising infectious proteins, or combinations thereof.

20. The decontamination solution according to claim 12, wherein said decontamination solution is capable of oxidizing at least about 95% of a chemical agent or a biological agent.

21. The decontamination solution according to claim 13, wherein said decontamination solution is capable of oxidizing at least about 95% of a chemical agent or a biological agent, and wherein said chemical or biological agent comprise mustard gas, nerve gas, soman (1,2,2-trimethylpropyl methylphosphonofluoridic acid ester), a blister agent, thioanisole, a toxic industrial material, a toxic industrial chemical, anthrax, an endospore, a fungi, a bacterial, a protozoa, a prion, a virus, ricin, T-2-mycotoxon, bird flu, C-difficile, polio, small pox, pneumonia, ricin, or T-2-nycotox, or combinations thereof.

22. The decontamination solution according to claim 14, wherein said decontamination solution is capable of oxidizing at least about 97% of a chemical or biological agent, and wherein said chemical or biological agent comprises mustard gas HD (bis(2-chloroethyl) sulfide;

nerve gas VX (S-[2-[bis-(1-methylethyl)amino]ethyl o-ethyl-methyl phosphonothioic acid ester, soman (1,2,2-trimethylpropyl methylphosphonofluoridic acid ester, a blister agent, small pox, polio, pneumonia, anthrax, ricin, T-2-mycotoxin, toxin industrial materials, toxin industrial chemicals, bird flu, C-difficile, HIV, endospores comprising Geobacillus stearothermophilus, Bacillus subtilis, Bacillus subtilis globigii, Clostridium sporogenes, Bacillus cereus, and Bacillus circulans, fungi comprising Aspergillus niger, Candida albicans, Trichophyton mentagrophytes, and Wangiella dermatitis, mycrobacteria comprising Mycobacterium chelonae, Mycobacterium gordonae, Mycobacterium smegmatis, and Mycobacterium terrae, vegetative bacteria comprising Aeromonas hydrophila, Enterococcus faecalis, Streptococcus faecalis, Enterococcus faecium, Streptococcus pyrogenes, Escherichia coli, Klebsiella (pneumoniae), Legionella pneumophila, Methylobacterium, Pseudomonas aeruginosa, Salmonella choleraesuis, Helicobacter pylori, Staphylococcus aureus, Staphylococcus epidermidis, and Stenotrophomonas maltophilia, protozoa comprising Giardia lamblia and Cryptosporidium parvum, or prions comprising infectious proteins, or combinations thereof.

23. The decontamination solution according to claim 15, wherein said decontamination solution is capable of oxidizing at least about 99% of a chemical or biological agent, and wherein said chemical or biological agent comprises mustard gas HD (bis(2-chloroethyl) sulfide;

nerve gas VX (S-[2-[bis-(1-methylethyl)amino]ethyl] o-ethyl-methyl phosphonothioic acid ester, soman (1,2,2-trimethylpropyl methylphosphonofluoridic acid ester, a blister agent, small pox, polio, pneumonia, anthrax, ricin, T-2-mycotoxin, toxin industrial materials, toxin industrial chemicals, bird flu, C-difficile, HIV, endospores comprising Geobacillus stearothermophilus, Bacillus subtilis, Bacillus subtilis globigli, Clostridium sporogenes, Bacillus cereus, and Bacillus circulans, fungi comprising Aspergillus niger, Candida albicans, Trichophyton mentagrophytes, and Wangiella dermatitis, mycrobacteria comprising Mycobacterium chelonae, Mycobacterium gordonae, Mycobacterium smegmatis, and Mycobacterium terrae, vegetative bacteria comprising Aeromonas hydrophila, Enterococcus faecalis, Streptococcus faecalis, Enterococcus faecium, Streptococcus pyrogenes, Escherichia coli, Klebsiella (pneumoniae), Legionella pneumophila, Methylobacterium, Pseudomonas aeruginosa, Salmonella choleraesuis, Helicobacter pylori, Staphylococcus aureus, Staphylococcus epidermidis, and Stenotrophomonas maltophilia, protozoa comprising Giardia lamblia and Cryptosporidium parvum, or prions comprising infectious proteins, or combinations thereof.

24. The decontamination composition according to claim 2, wherein said composition is capable of eradicating at least 90% of a chemical or a biological agent within about 30 minutes upon application of said composition thereto.

25. The decontamination composition according to claim 3, wherein said composition is capable of eradicating at least 95% of a chemical or a biological agent within about 30 minutes upon application of said composition thereto.

26. The decontamination composition according to claim 6, wherein said composition is capable of eradicating at least 95% of a chemical or a biological agent within about 15 minutes upon application of said composition thereto.

27. The decontamination composition according to claim 1, wherein said composition is capable of eradicating at least about 95% by weight of a chemical or a biological agent comprising soman or Bacillus subtilis in about 3 minutes or less.

28. The decontamination composition according to claim 4, wherein said composition is capable of eradicating at least about 95% by weight of a chemical or a biological agent comprising soman or Bacillus subtilis in about 3 minutes or less.

29. The decontamination composition according to claim 6, wherein said composition is capable of eradicating at least about 97% by weight of a chemical or a biological agent comprising soman or Bacillus subtilis in about 2 minutes or less.

30. A process for making a one part, solids containing decontamination blend composition;

comprising the steps of;

mixing an acetyl donor coated with a hydrolysis resistant compound, a peroxygen source capable of generating a peroxygen compound in the presence of water, an optional catalyst, an optional surfactant, and an optional buffer to form the one part solids containing blend, and wherein said acetyl donor is a source of peracetic acid.

31. The process according to claim 30,

wherein said coating compound comprises an organic acid comprising carboxylic and dicarboxylic acids;

a weak mineral acid;

a cellulosic compound;

a long chain soluble alcohol;

a fatty acid, or a fatty acid salt, or mixtures thereof;

a polymer;

a gelatin;

a maltodextrin;

a sugar;

or a latex;

or combinations thereof;

wherein the amount of said acetyl donor is from about 10% to about 70% by weight;

wherein the amount of said peroxygen source is from about 10% to about 70% by weight;

wherein the amount of said coating compound is from about 1% to about 20% by weight, and

wherein said weight percentages are based upon the total weight of said acetyl donor, said coating compound, a said peroxygen source, said optional catalysts;

said optional surfactant, and said optional buffer.

32. The process according to claim 31, including forming said one part solids containing blend into a free flowing blend, or into an integral solid form.

33. The process according to claim 32, including at least one buffer, and including at least one surfactant,

wherein said acetyl donor comprises acetylsalicylic acid (aspirin), acetic anhydride, tetraacetylethylenediamine (TAED), pentaacetyl glucose, acetylcholine, or acetyl borate derivatives, or combinations thereof;

wherein said peroxygen source is a percarbonate salt comprising sodium percarbonate or potassium percarbonate, a perborate salt comprising a sodium perborate or potassium perborate, a persulfate salt comprising sodium persulfate or potassium persulfate, calcium peroxide, magnesium peroxide, urea peroxide, potassium monopersulfate (oxone), peroxydone, or combinations thereof;

wherein said coating compound comprises a carboxylic acid having from 1 to 20 carbon atoms, a dicarboxylic acid having from 2 to 8 carbon atoms, boric acid, hydroxy propyl methyl cellulose, hydroxylpropyl cellulose, hydroxyethyl cellulose, ethyl cellulose, acetyl cellulose, benzyl cellulose, cellulose acetobutylate, cellulose acetylphthalate, polyvinyl alcohol, polymethyl methacrylate copolymer, acrylic resin, lactic acid, glycolic acid oligomer, polyethylene glycol, polyvinyl pyrolidone, polycaprolactone, polyorthoester, or polyanhydride, or combinations thereof;

wherein the amount of said acetyl donor is from about 15% to about 55% by weight, wherein the amount of said coating compound is from about 1.25% to about 15% by weight, wherein the amount of said peroxygen source is from about 15% to about 60% by weight, wherein the amount of said buffer is from about 5% to about 50% by weight and wherein the amount of said surfactant is from about 0.1% to about 10% by weight;

wherein said weight percentages are based upon the total weight of said acetyl donor, said coating material, said peroxygen source, said buffer, said surfactant, and said catalysts.

34. The process according to claim 33, including at least one catalyst comprising a non-metal catalysts, a transition metal catalyst or a non-metal transition catalyst, wherein said catalyst is a molybdate compound or a tungsten compound, wherein the amount of said catalyst is from about 0.1 to about 6% by weight based upon the total weight of said acetyl donor, said coating compound, said peroxygen source, said catalyst, said surfactant, and said buffer;

wherein said acetyl donor acetylsalicylic acid, tetraacetylethylenediamine (TAED), acetylcholine, or pentaacetyl glucose, or combinations thereof;

wherein said coating compound is citric acid, boric acid, or salicylic acid, or combinations thereof;

wherein said peroxygen source is sodium percarbonate, sodium perborate, urea peroxide, oxone or peroxydone, or combinations thereof;

wherein said buffer is potassium bicarbonate, potassium carbonate, borax, or puffed borax, or combinations thereof, and

wherein said surfactant is an anionic surfactant, a nonanionic surfactant, or a catanionic surfactant.

35. The process according to claim 34, wherein the amount of said acetyl donor is from about 20% to about 35% by weight, wherein the amount of said coating compound is from about 1.5% to about 10% by weight, and wherein the amount of said peroxygen source is from about 30% to about 45% by weight.

36. The process according to claim 30, including adding water so that peracetic acid is generated.

37. The process according to claim 31, including adding water so that peracetic acid is generated in an amount of from about 0.5% to about 15% by weight based upon the total weight of said decontamination blend composition and the water.

38. The process according to claim 33, including adding an amount of water so that peracetic acid is generated in an amount of from about 0.5% to about 10% by weight based upon the total weight of said decontamination blend composition and the water.

39. The process according to claim 34, including adding an amount of water so that peracetic acid is generated in an amount of from about 1% to about 3% by weight based upon the total weight of said decontamination blend composition and the water.

40. The process according to claim 30, including diluting said decontamination blend composition with water to from a decontamination solution, wherein said amount of water is from about 100 parts to about 4,000 parts by weight per every 100 parts by weight of said decontamination blend composition.

41. The process according to claim 33, including diluting said decontamination blend composition with water to form a decontamination solution wherein said amount of water is from about 200 parts to about 2,000 parts by weight per every 100 parts by weight of said decontamination blend composition;

and

applying said diluted composition to a chemical agent, or a biological agent, or combinations thereof.

42. The process according to claim 34, including diluting said decontamination blend composition with water to form a decontamination solution, wherein said amount of water is from about 500 parts to about 1,000 parts by weight per every 100 parts by weight of said decontamination blend composition;

and

applying said diluted composition to a chemical agent, or a biological agent, or combinations thereof.

43. The process according to claim 40, including applying said decontamination solution to a chemical agent, or a biological agent, or both, wherein said chemical and biological agents comprises mustard gas, nerve gas, soman (1,2,2-trimethylpropyl methylphosphonofluoridic acid ester), a blister agent, thioanisole, a toxic industrial material, a toxic industrial chemical, anthrax, an endospore, a fungi, a bacterial, a protozoa, a prion, a virus, ricin, T-2-mycotoxon, bird flu, C-difficile, polio, small pox, pneumonia, ricin, or T-2-nycotox, or combinations thereof.

44. The process according to claim 40, including applying said decontamination solution to a chemical agent, or a biological agent, or both, wherein said chemical and biological agents comprise mustard gas HD (bis(2-chloroethyl) sulfide;

nerve gas VX (S-[2-[bis-(1-methylethyl)amino] ethyl o-ethyl-methyl phosphonothioic acid ester, soman (1,2,2-trimethylpropyl methylphosphonofluoridic acid ester, a blister agent, small pox, polio, pneumonia, anthrax, ricin, T-2-mycotoxin, toxin industrial materials, toxin industrial chemicals, bird flu, C-difficile, HIV, endospores comprising Geobacillus stearothermophilus, Bacillus subtilis, Bacillus subtilis globigli, Clostridium sporogenes, Bacillus cereus, and Bacillus circulans, fungi comprising Aspergillus niger, Candida albicans, Trichophyton mentagrophytes, and Wangiella dermatitis, mycrobacteria comprising Mycobacterium chelonae, Mycobacterium gordonae, Mycobacterium smegmatis, and Mycobacterium terrae, vegetative bacteria comprising Aeromonas hydrophila, Enterococcus faecalis, Streptococcus faecalis, Enterococcus faecium, Streptococcus pyrogenes, Escherichia coli, Klebsiella (pneumoniae), Legionella pneumophila, Methylobacterium, Pseudomonas aeruginosa, Salmonella choleraesuis, Helicobacter pylori, Staphylococcus aureus, Staphylococcus epidermidis, and Stenotrophomonas maltophilia, protozoa comprising Giardia lamblia and Cryptosporidium parvum, or prions comprising infectious proteins, or combinations thereof.

45. The process according to claim 41, including applying said decontamination solution to a chemical agent, or a biological agent, or both, wherein said chemical and biological agents comprises mustard gas, nerve gas, soman (1,2,2-trimethylpropyl methylphosphonofluoridic acid ester), a blister agent, thioanisole, a toxic industrial material, a toxic industrial chemical, anthrax, an endospore, a fungi, a bacterial, a protozoa, a prion, a virus, ricin, T-2-mycotoxon, bird flu, C-difficile, polio, small pox, pneumonia, ricin, or T-2-nycotox, or combinations thereof.

46. The process according to claim 41, including applying said decontamination solution to a chemical agent, or a biological agent, or both, wherein said chemical and biological agents comprise mustard gas HD (bis(2-chloroethyl) sulfide;

nerve gas VX (S-[2-[bis-(1-methylethyl)amino]ethyl] o-ethyl-methyl phosphonothioic acid ester, soman (1,2,2-trimethylpropyl methylphosphonofluoridic acid ester, a blister agent, small pox, polio, pneumonia, anthrax, ricin, T-2-mycotoxin, toxin industrial materials, toxin industrial chemicals, bird flu, C-difficile, HIV, endospores comprising Geobacillus stearothermophilus, Bacillus subtilis, Bacillus subtilis globigii, Clostridium sporogenes, Bacillus cereus, and Bacillus circulans, fungi comprising Aspergillus niger, Candida albicans, Trichophyton mentagrophytes, and Wangiella dermatitis, mycrobacteria comprising Mycobacterium chelonae, Mycobacterium gordonae, Mycobacterium smegmatis, and Mycobacterium terrae, vegetative bacteria comprising Aeromonas hydrophila, Enterococcus faecalis, Streptococcus faecalis, Enterococcus faecium, Streptococcus pyrogenes, Escherichia coli, Klebsiella (pneumoniae), Legionella pneumophila, Methylobacterium, Pseudomonas aeruginosa, Salmonella choleraesuis, Helicobacter pylon, Staphylococcus aureus, Staphylococcus epidermidis, and Stenotrophomonas maltophilia, protozoa comprising Giardia lamblia and Cryptosporidium parvum, or prions comprising infectious proteins, or combinations thereof.

47. The process according to claim 42, including applying said decontamination solution to a chemical agent, or a biological agent, or both, wherein said chemical and biological agents comprises mustard gas, nerve gas, soman (1,2,2-trimethylpropyl methylphosphonofluoridic acid ester), a blister agent, thioanisole, a toxic industrial material, a toxic industrial chemical, anthrax, an endospore, a fungi, a bacterial, a protozoa, a prion, a virus, ricin, T-2-mycotoxon, bird flu, C-difficile, polio, small pox, pneumonia, ricin, or T-2-nycotox, or combinations thereof.

48. The process according to claim 43, including applying said decontamination solution to a chemical agent, or a biological agent, or both, wherein said chemical and biological agents comprise mustard gas HD (bis(2-chloroethyl) sulfide;

nerve gas VX (S-[2-[bis-(1-methylethyl)amino]ethyl o-ethyl-methyl phosphonothioic acid ester, soman (1,2,2-trimethylpropyl methylphosphonofluoridic acid ester, a blister agent, small pox, polio, pneumonia, anthrax, ricin, T-2-mycotoxin, toxin industrial materials, toxin industrial chemicals, bird flu, C-difficile, HIV, endospores comprising Geobacillus stearothermophilus, Bacillus subtilis, Bacillus subtilis globigii, Clostridium sporogenes, Bacillus cereus, and Bacillus circulans, fungi comprising Aspergillus niger, Candida albicans, Trichophyton mentagrophytes, and Wangiella dermatitis, mycrobacteria comprising Mycobacterium chelonae, Mycobacterium gordonae, Mycobacterium smegmatis, and Mycobacterium terrae, vegetative bacteria comprising Aeromonas hydrophila, Enterococcus faecalis, Streptococcus faecalis, Enterococcus faecium, Streptococcus pyrogenes, Escherichia coli, Klebsiella (pneumoniae), Legionella pneumophila, Methylobacterium, Pseudomonas aeruginosa, Salmonella choleraesuis, Helicobacter pylori, Staphylococcus aureus, Staphylococcus epidermidis, and Stenotrophomonas maltophilia, protozoa comprising Giardia lamblia and Cryptosporidium parvum, or prions comprising infectious proteins, or combinations thereof.