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Integrated portable biological detection system

  • US 20080047832A1
  • Filed: 02/05/2007
  • Published: 02/28/2008
  • Est. Priority Date: 07/07/1994
  • Status: Active Grant
First Claim
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1. An integrated system for the analysis of eukaroytic and/or prokaryotic cells in a biological sample comprising:

  • an electronic system for cell separation, cell lysis, sample preparation, and sample analysis further comprising a flow cell, an input port coupled to the flow cell, an output port coupled to the flow cell, a plurality of individually addressable electrodes positioned within the flow cell and coupled to a power source configured to electronically disrupt cell membranes within the sample, and an array of probes coupled to the electrodes and adapted to bind to predetermined components within the sample for analysis of the components, and a heating element coupled to the flow cell, wherein the flow cell is adapted to receive the sample via the input;

    a detector operatively positioned to detect the molecules bound to the probes by a detectable signal;

    a power source coupled to the flow cell; and

    a portable housing configured to contain the electronic system, the detector, and the power source.

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