Device for storing and transporting microneedles and a method for delivering active substances with the aid of such a device

• US 20080051723A1
• Filed: 06/25/2007
• Published: 02/28/2008
• Est. Priority Date: 06/23/2006
• Status: Abandoned Application

• Current Assignee: Robert Bosch GmbH
• Original Assignee: Robert Bosch GmbH
• Inventors: Laermer, Franz, Cassemeyer, Julia, Stumber, Michael, Scholten, Dick, Maeurer, Christian
• Application Number:
  US11/821,994
• Publication Number:
  US 20080051723A1
• Time in Patent Office: Days
• US Class Current: 604/191
• CPC Class Codes: A61M 2037/0023 Drug applicators using microneedles
• CPC Class Codes: A61M 2037/0061 Methods for using microneedles
• CPC Class Codes: A61M 37/0015 by using microneedles
• CPC Class Codes: B65D 81/22 in moist conditions or immersed in liquids
• CPC Class Codes: B65D 85/24 for needles, nails or like elongate small articles

Abstract

A device for storing and transporting microneedles and a method for delivering active substances with the aid of such a device. In the device for storing and transporting microneedles, a reservoir is provided which contains an active substance for delivery by the microneedles and the microneedles are situated within a package forming the reservoir.

Claims

1. A device for storing and transporting microneedles comprising:

a package for containing the microneedles, the package forming a reservoir, the reservoir containing an active substance for delivery by the microneedles.

2. The device according to claim 1, wherein the microneedles are mounted on a substrate permeable to the active substance.

3. The device according to claim 2, wherein the substrate permeable to the active substance extends through the reservoir, subdividing the reservoir into a first reservoir region having microneedles, and a second reservoir region without microneedles.

4. The device according to claim 2, wherein the package is formed by an elastic film, perforatable by the microneedles, and an outer layer, which are connected to each other at their edge areas.

5. The device according to claim 4, wherein at least one of the elastic film and the substrate has adhesive properties, at least in their edge areas, which makes it possible to glue the elastic film and the substrate together by exerting a pressure.

6. The device according to claim 1, wherein the microneedles are situated in an array and have needle tips on a substrate.

7. The device according to claim 1, wherein the microneedles are made of at least one of silicon, plastic, and metal.

8. A method for delivering an active substance with the aid of a device having microneedles, which are situated within a package forming a reservoir for the active substance, the method comprising:

applying the device to a skin to be treated;

exerting a pressure on the device, so that the microneedles perforate the package and penetrate the skin; and

transporting the active substance from the reservoir into the skin via the microneedles.

9. The method according to claim 8, wherein the package having an elastic film and an outer layer, which are connected at their edge areas, and the microneedles are used, which are mounted on a substrate permeable to the active substance and extending through the reservoir, wherein, when pressure is exerted on the device, the substrate is pressed against the elastic film and the microneedles perforate the elastic film.

10. The method according to claim 9, wherein at least one of the elastic film and the substrate having adhesive properties at least in their edge areas is used, wherein, when pressure is exerted on the device, the elastic film and the substrate are glued together, securing the microneedles and holding the microneedles in place.