Medical devices comprising porous layers for the release of therapeutic agents
First Claim
1. An implantable or insertable medical device comprising a substrate region, a porous layer disposed over said substrate region, a therapeutic agent disposed beneath said porous layer, and a biodegradable material disposed beneath said porous layer that regulates the release of said therapeutic agent from said medical device into a subject upon implantation or insertion of said device into said subject.
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Accused Products
Abstract
In accordance with an aspect of the invention, implantable or insertable medical devices are provided in which a porous layer is disposed over a therapeutic-agent-containing region. In accordance with another aspect of the invention, medical devices are fabricated by a method in which a porous layer is deposited over a therapeutic-agent-containing region using a field-injection-based electrospray technique.
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Citations
35 Claims
- 1. An implantable or insertable medical device comprising a substrate region, a porous layer disposed over said substrate region, a therapeutic agent disposed beneath said porous layer, and a biodegradable material disposed beneath said porous layer that regulates the release of said therapeutic agent from said medical device into a subject upon implantation or insertion of said device into said subject.
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32. A method of forming a medical device comprising depositing a porous layer over a therapeutic-agent-containing region using a field-injection-based electrospray technique.
Specification