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Pharmaceutical Compositions

  • US 20080058353A1
  • Filed: 08/20/2007
  • Published: 03/06/2008
  • Est. Priority Date: 08/21/2006
  • Status: Active Grant
First Claim
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1. A pharmaceutical composition comprising:

  • {1S-[1α

    , 2α

    , 3β

    (1S*,2R*),5β

    ]}-3-(7-{[2-(3,4difluorophenyl)cyclopropyl]amino}-5-(propylthio)-3H-1,2,3-triazolo[4,5-d]pyrimidin-3-yl)-5-(2-hydroxyethoxy)cyclopentane-1,2-diol;

    one or more fillers selected from mannitol, sorbitol, dibasic calcium phosphate dihydrate, dibasic calcium phosphate anhydrate, and tribasic calcium phosphate, or any mixture thereof, one or more binders selected from hydroxypropyl cellulose, alginic acid, carboxymethylcellulose sodium, copovidone, and methylcellulose, or any mixture thereof;

    one or more disintegrants selected from sodium starch glycolate, croscarmellose sodium, and crospovidone, or any mixture thereof, and one or more lubricants.

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