Analyte sensors and methods

• US 20080060196A1
• Filed: 10/30/2007
• Published: 03/13/2008
• Est. Priority Date: 08/01/2006
• Status: Active Grant

• Current Assignee: Abbott Diabetes Care Incorporated (Abbott Laboratories Incorporated)
• Original Assignee: Abbott Diabetes Care Incorporated (Abbott Laboratories Incorporated)
• Inventors: Wang, Yi, Feldman, Benjamin
• Granted Patent: US 7,918,012 B2
• Time in Patent Office: Days
• US Class Current: 29/854
• CPC Class Codes: G01N 27/3271 Amperometric enzyme electrodes for analytes in body fluids, e.g. glucose in blood amperometry per se G01N27/49; aspects concerning the enzyme reagent C12Q1/001
• CPC Class Codes: G01N 27/3272 Test elements therefor, i.e. disposable laminated substrates with electrodes, reagent and channels optical biosensors G01N33/52
• CPC Class Codes: G01N 27/3274 Corrective measures, e.g. error detection, compensation for temperature or hematocrit, calibration coding of calibration information G01N33/48771
• CPC Class Codes: Y10T 29/49002 Electrical device making
• CPC Class Codes: Y10T 29/49004 including measuring or testing of device or component part
• CPC Class Codes: Y10T 29/49117 Conductor or circuit manufacturing
• CPC Class Codes: Y10T 29/49126 Assembling bases
• CPC Class Codes: Y10T 29/49128 Assembling formed circuit to base
• CPC Class Codes: Y10T 29/4913 Assembling to base an electrical component, e.g., capacitor, etc.
• CPC Class Codes: Y10T 29/49135 and shaping, e.g., cutting or bending, etc.
• CPC Class Codes: Y10T 29/49155 Manufacturing circuit on or in base
• CPC Class Codes: Y10T 29/49156 with selective destruction of conductive paths
• CPC Class Codes: Y10T 29/49169 Assembling electrical component directly to terminal or elongated conductor
• CPC Class Codes: Y10T 29/49204 Contact or terminal manufacturing

Abstract

A sensor, and methods of making, for determining the concentration of an analyte, such as glucose, in a biological fluid such as blood or serum, using techniques such as coulometry, amperometry, and potentiometry. The sensor includes a working electrode and a counter electrode, and may include an insertion monitoring trace to determine correct positioning of the sensor in a connector. The sensor is calibration-adjusted, eliminating the need for a user to enter a calibration code or for the meter to read a calibration code.

Claims

1. A method of making a plurality of calibration-adjusted sensors comprising:

(a) measuring a property of a component;

(b) forming a web construction comprising the component;

(c) obtaining a first sensor from the web construction, the first sensor having a slope and y-intercept,

(d) comparing the slope and y-intercept from the first sensor to a desired slope and y-intercept; and

(e) obtaining a second sensor from the web construction, the second sensor having the desired slope and y-intercept.

2. The method of claim 1 further comprising:

(c) forming a third sensor, the third sensor having the desired slope and y-intercept.

3. The method of claim 2, wherein the second sensor and the third sensor are physically different than the first sensor.

4. The method of claim 3, wherein the second sensor and the third sensor are physically different than the first sensor by an electrode area.

5. The method of claim 3, wherein the second sensor and the third sensor are physically different than the first sensor by a sample chamber volume.

6. The method of claim 1, wherein the slope and y-intercept of the first sensor is different than the desired slope and y-intercept.