Color changing skin sealant with co-acid trigger

• US 20080060550A1
• Filed: 12/19/2006
• Published: 03/13/2008
• Est. Priority Date: 09/12/2006
• Status: Abandoned Application

• Current Assignee: Kimberly-Clark Worldwide Incorporated (Kimberly-Clark Corporation)
• Original Assignee: Kimberly-Clark Worldwide Incorporated (Kimberly-Clark Corporation)
• Inventors: Schorr, Phill, Weart, Illona Furman, MacDonald, Gavin, Smith, Molly K., Arehart, Kelly
• Application Number:
  US11/642,359
• Publication Number:
  US 20080060550A1
• Time in Patent Office: Days
• US Class Current: 106/162.1
• CPC Class Codes: A61L 24/001 Use of materials characterised by their function or physical properties
• CPC Class Codes: C09D 4/00 Coating compositions, e.g. paints, varnishes or lacquers, based on organic non-macromolecular compounds having at least one polymerisable carbon-to-carbon unsaturated bond ; Coating compositions, based on monomers of macromolecular compounds of groups C09D183/00 - C09D183/16

Abstract

Skin sealants are applied over skin preps to seal the skin and hold any remaining bacteria in place prior to incisions. It is desirable for the person applying the sealant to know where the sealant has been applied. It is also desirable to be able so see through the sealant to observe the skin to detect any possible infection. A skin sealant is provided that has a pH indicator and co-additive acid that react soon after mixing, rendering the skin prep colorless.

Claims

1. A curable coating comprising a mutable color changing composition.

2. The coating of claim 1 wherein said composition comprises a pH indicator, acid and skin sealant.

3. The coating of claim 2 wherein said sealant is a cyanoacrylate, polysaccharide, silicone, polyvinylpyrolidone, gelatin, polysiloxane-polyether or a mixture thereof.

4. The coating of claim 1 wherein said mutability is triggered by acid.

5. The coating of claim 4 wherein said acid is an organic acid selected from citric, ascorbic, malic, acetic, propanoic, malonic and cysteine.

6. The coating of claim 2 wherein said pH indicator is an organic dye or a metal salt colorant.

7. The coating of claim 6 wherein said pH indicator is a metal tannate salt

8. The coating of claim 2 wherein said pH indicator is selected from anionic xanthene dyes, carotenoid dyes quinone dyes.

9. The coating of claim 8 wherein said pH indicator is selected from rose bengal, trans-β

-carotene, disperse blue 3,1-amino-4-hydroxyanthraquinone, or iron tannate.

10. The coating of claim 1 wherein said color change occurs after mixing said indicator, acid and sealant within 10 minutes.

11. The coating of claim 1 wherein said color change occurs after mixing said indicator, acid and sealant within 5 minutes.

12. The coating of claim 1 wherein said color change occurs after mixing said indicator, acid and sealant within 3 minutes.

13. The coating of claim 2 wherein said pH indicator is present in an amount between about 0.09 and 1.5 weight percent of the sealant.

14. A curable coating comprising a triggerable pH indicator, an acid trigger and a skin sealant.

15. The coating of claim 14 wherein said pH indicator is impregnated onto a foam which is used to apply said sealant.

16. The coating of claim 14 wherein said pH indicator is applied separately from said skin sealant from a separate reservoir.

17. The coating of claim 14 wherein said pH indicator is applied simultaneously with said skin sealant but from a separate reservoir.

18. The coating of claim 14 used to cover wounds, bruises, abrasions, burns, acne, blisters, bites, stings, punctures, splinters, cuts and other disruptions in the skin to protect them from subsequent contamination.

19. The coating of claim 14 used to close wounds.

20. The coating of claim 14 is packaged in a “

kit”

form.