Retrievable implant and method for treatment of mitral regurgitation

• US 20080065205A1
• Filed: 09/11/2006
• Published: 03/13/2008
• Est. Priority Date: 09/11/2006
• Status: Abandoned Application

• Current Assignee: Edwards Lifesciences Corporation
• Original Assignee: Edwards Lifesciences Corporation
• Inventors: Nguyen, Kim, Nguyen, Duy
• Application Number:
  US11/519,519
• Publication Number:
  US 20080065205A1
• Time in Patent Office: Days
• US Class Current: 623/2.36
• CPC Class Codes: A61F 2/2451 Inserts in the coronary sinus for correcting the valve shape
• CPC Class Codes: A61F 2/2466 Delivery devices therefor
• CPC Class Codes: A61F 2/885 comprising a coil including a plurality of spiral or helical sections with alternate directions around a central axis
• CPC Class Codes: A61F 2250/0098 radio-opaque, e.g. radio-opaque markers

Abstract

The invention is a device, and method for deploying same, configured for placement in a body lumen such as a coronary sinus, as may be desired to repair a mitral valve. The device includes a first anchor, a second anchor, and a bridge. The anchors are configured to delivered to a desired deployment site within the body lumen in a collapsed or contracted condition, and then be deployed by expanding the anchors into contact with the walls of the body lumen. One or more of the anchors may be configured to be radially collapsible after initial deployment in order to permit the anchor(s) to be repositioned in or removed from the body lumen. An anchor may be collapsible in response to a distal force applied to a portion of a proximal end thereof. A catheter for use with the implant is configured to deliver the implant to the site with the anchors in their respective collapsed configurations, and to release the anchors to permit them to expand into contact with the walls of the body lumen. The catheter is configured to apply a proximal force to one or both anchors, which may be applied via a cinch wire. The catheter may also be configured to apply a distal force against a portion of the proximal end of one or more of the anchors.

Claims

1. An implant for placement in a coronary sinus of a patient, comprising:

a first anchor configured to be expanded from a contracted condition to an expanded condition, the first anchor having a distal end and a proximal end, the first anchor configured to radially collapse to a contracted condition in response to the application of a longitudinal force applied at a portion of the proximal end of the first anchor, the anchor configured to have a generally unobstructed central lumen passing therethrough when in the expanded configuration,

a second anchor having a distal end and a proximal end, and

a bridge having a first end and a second end, wherein the first end of the bridge is secured to the first anchor and the second end of the bridge is secured to the second anchor.

2. The implant of claim 1, wherein the proximal end of the first anchor has a generally tapered shape.

3. The implant of claim 2, wherein the proximal end of the first anchor has a generally dome-like shape.

4. The implant of claim 2, wherein the proximal end of the first anchor has a generally wedge-like shape.

5. The implant of claim 1, wherein the second anchor is a distal anchor, and the second end of the bridge is fixedly secured to the second anchor.

6. The implant of claim 1, wherein the first end of the bridge is slidingly secured to the first anchor, and the implant further comprises:

a lock configured to fixedly secure the first end of the bridge with respect to the first anchor.

7. The implant of claim 6, wherein the lock is a one-way lock that prevents sliding movement of the first end of the bridge in a first direction with respect to the first anchor, and wherein the lock permits sliding movement of the first end of the bridge in a second direction with respect to the first anchor, and wherein the second direction is opposite to the first direction.

8. An implant for placement in a coronary sinus of a patient, comprising:

a first anchor having a distal end and a proximal end, the first anchor configured to expand from a contracted condition to an expanded condition, the first anchor having a first generally helical coil and configured to radially collapse in response to the application of a longitudinal force applied at a portion of the proximal end of the first anchor, the radial coil defining an outer diameter of the first anchor in the expanded condition,

a second anchor having a distal end and a proximal end, and

a bridge having a first end and a second end, wherein the first end of the bridge is secured to the first anchor and the second end of the bridge is secured to the second anchor.

9. The implant of claim 8, wherein the first anchor comprises a self-expanding memory material.

10. The implant of claim 8, wherein the first anchor comprises a second generally helical coil.

11. The implant of claim 10, wherein the first helical coil coils in a first direction, and the second helical coil coils in a second direction, wherein the first direction is opposite to the second direction.

12. The implant of claim 8, wherein the first anchor further comprises a covering over the first helical coil.

13. The implant of claim 8, wherein second anchor has a first generally helical coil and is configured to radially collapse in response to the application of a longitudinal force applied at a portion of the proximal end of the second anchor.

14. A method of deploying an implant in a body lumen, wherein the implant includes a first anchor, a second anchor, and a bridge connecting the first anchor to the second anchor, the method comprising:

advancing the first anchor to a first anchor deployment location within a body lumen;

expanding the first anchor to an expanded condition to deploy the first anchor within a body lumen, wherein the first anchor expands into contact with the walls of the body lumen with substantially all of the first anchor structure positioned at or adjacent the walls of the body lumen to thereby leave the body lumen substantially open and unblocked;

advancing the second anchor to a second anchor deployment location within a body lumen;

expanding the second anchor to deploy the second anchor within the body lumen, wherein the second anchor expands into contact with the walls of the body lumen;

after the step of expanding the first anchor to an expanded condition, the further step of contracting the first anchor from its expanded condition to a contracted condition wherein the first anchor has a diameter significantly smaller than the diameter of the body lumen so that the first anchor can be moved proximally or distally within the body lumen.

15. The method of claim 14, further comprising:

after the step of contracting the first anchor from its expanded condition to a contracted condition, the further step of proximally moving the first anchor within the body lumen.

16. The method of claim 15, further comprising:

after the step of proximally moving the first anchor within the body lumen, the further step of re-expanding the first anchor to an expanded condition to deploy the first anchor within a body lumen, wherein the first anchor re-expands into contact with the walls of the body lumen

17. The method of claim 15, further comprising:

after the step of proximally moving the first anchor within the body lumen, the further step of removing the implant from within the body lumen.

18. The method of claim 14, wherein the first anchor is a proximal anchor and the second anchor is a distal anchor.

19. The method of claim 18, wherein the step of expanding the second anchor to deploy the second anchor within the body lumen is performed prior to the step of expanding the first anchor to an expanded condition to deploy the first anchor within a body lumen.

20. The method of claim 19, further comprising:

after the step of expanding the second anchor to deploy the second anchor within the body lumen, the further step of adjusting the length of the bridge between the first anchor and the second anchor.