Enhanced optical coherence tomography for anatomical mapping
First Claim
1. A method for generating a partial fundus image from a 3-D data set defined by Z-axis intensity information for a plurality of X and Y positions acquired by scanning the eye with an optical coherence tomographic (OCT) device, said method comprising the steps of:
- segmenting the data to define a volume as a function of a selected depth within the eye and a selected range from that depth;
integrating the intensity information along line extending between the selected depth and the selected range to create a single intensity value at a plurality of X and Y positions; and
displaying a 2-D image of the integrated intensity values.
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Abstract
A system, method and apparatus for anatomical mapping utilizing optical coherence tomography. In the present invention, 3-dimensional fundus intensity imagery can be acquired from a scanning of light back-reflected from an eye. The scanning can include spectral domain scanning, as an example. A fundus intensity image can be acquired in real-time. The 3-dimensional data set can be reduced to generate an anatomical mapping, such as an edema mapping and a thickness mapping. Optionally, a partial fundus intensity image can be produced from the scanning of the eye to generate an en face view of the retinal structure of the eye without first requiring a full segmentation of the 3-D data set. Advantageously, the system, method and apparatus of the present invention can provide quantitative three-dimensional information about the spatial location and extent of macular edema and other pathologies. This three-dimensional information can be used to determine the need for treatment, monitor the effectiveness of treatment and identify the return of fluid that may signal the need for re-treatment.
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Citations
23 Claims
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1. A method for generating a partial fundus image from a 3-D data set defined by Z-axis intensity information for a plurality of X and Y positions acquired by scanning the eye with an optical coherence tomographic (OCT) device, said method comprising the steps of:
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segmenting the data to define a volume as a function of a selected depth within the eye and a selected range from that depth;
integrating the intensity information along line extending between the selected depth and the selected range to create a single intensity value at a plurality of X and Y positions; and
displaying a 2-D image of the integrated intensity values. - View Dependent Claims (2, 3, 4)
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5. A method for generating a partial fundus image from a 3-D data set defined by Z-axis intensity information for a plurality of X and Y positions acquired by scanning the eye with an optical coherence tomographic (OCT) device, said method comprising the steps of:
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identifying a reference surface within the eye from the 3-D data set;
integrating the intensity information along a line extending between the surface and a selected range from that surface to create a single intensity value at a plurality of X and Y positions; and
displaying a 2-D image of the integrated intensity values. - View Dependent Claims (6, 7, 8, 9)
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10. A method for generating a partial fundus image from a 3-D data set defined by Z-axis intensity information for a plurality of X and Y positions acquired by scanning the eye with an optical coherence tomographic (OCT) device, said method comprising the steps of:
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integrating a selected portion of the intensity information over a depth range greater than the axial resolution of the OCT device to create a single intensity value at a plurality of X and Y positions, said portion being selected to isolate a particular anatomical region within the eye; and
displaying a 2-D image of the integrated intensity values. - View Dependent Claims (11)
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12. A method for generating a partial fundus image from a 3-D data set defined by Z-axis intensity information for a plurality of X and Y positions acquired by scanning the eye with an optical coherence tomographic (OCT) device, said method comprising the steps of:
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segmenting the data to identify a pair of spaced apart reference surfaces;
integrating the intensity information along a line extending between the surfaces to create a single intensity value at a plurality of X and Y positions; and
displaying a 2-D image of the integrated intensity values. - View Dependent Claims (13, 14, 15, 16)
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17. An apparatus for obtaining an image of the eye comprising:
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an optical coherence tomography (OCT) system, said system including a scanner for scanning a light beam in the X and Y directions over the eye, said system generating a plurality of sets of outputs, each set corresponding to varying intensities as a function of depth in the Z-axis at different X/Y positions; and
a processor for integrating a selected portion of the intensity information over a depth range greater than the axial resolution of the OCT device to create a single intensity value at a plurality of X and Y positions, said portion being selected to isolate a particular anatomical region within the eye. - View Dependent Claims (18, 19, 20, 21, 22, 23)
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Specification