NUCLEOTIDE SEQUENCE CODING FOR VARIABLE REGIONS OF BETA CHAINS OF HUMAN T LYMPHOCYTE RECEPTORS, CORRESPONDING PEPTIDE SEGMENTS AND THE DIAGNOSTIC AND THERAPEUTIC USES
First Claim
Patent Images
1. An antibody directed against an antigenic determinant of one or more of the peptides encoded by a sequence selected from the group consisting of to 387 of SEQ ID NO:
- 2, 54 to 395 of SEQ ID NO;
3, 18 to 329 of SEQ ID NO;
4, 28 to 366 of SEQ ID NO;
5, 2 to 238 of SEQ ID NO;
6, 72 to 410 of SEQ ID NO;
8, 42 to 380 of SEQ ID NO;
9, 10 to 351 of SEQ ID NO;
10, 2 to 238 of SEQ ID NO;
11, 1 to 294 of SEQ ID NO;
12, 31 to 369 of SEQ ID NO;
13, 18 to 356 of SEQ ID NO;
14, 58 to 345 of SEQ ID NO;
15, 112 to 450 of SEQ ID NO;
16, 16 to 354 of SEQ ID NO;
17, 30 to 368 of SEQ ID NO;
18, and 94 to 432 of SEQ ID NO;
19.
1 Assignment
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Accused Products
Abstract
The present invention relates to new nucleotide sequences coding for variable regions of β chains of human T lymphocyte receptors, corresponding peptide segments and the diagnostic and therapeutic uses.
72 Citations
10 Claims
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1. An antibody directed against an antigenic determinant of one or more of the peptides encoded by a sequence selected from the group consisting of to 387 of SEQ ID NO:
- 2,
54 to 395 of SEQ ID NO;
3,18 to 329 of SEQ ID NO;
4,28 to 366 of SEQ ID NO;
5,2 to 238 of SEQ ID NO;
6,72 to 410 of SEQ ID NO;
8,42 to 380 of SEQ ID NO;
9,10 to 351 of SEQ ID NO;
10,2 to 238 of SEQ ID NO;
11,1 to 294 of SEQ ID NO;
12,31 to 369 of SEQ ID NO;
13,18 to 356 of SEQ ID NO;
14,58 to 345 of SEQ ID NO;
15,112 to 450 of SEQ ID NO;
16,16 to 354 of SEQ ID NO;
17,30 to 368 of SEQ ID NO;
18, and94 to 432 of SEQ ID NO;
19. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10)
- 2,
Specification
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Current AssigneeAventis Pharma SA (Sanofi )
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Original AssigneeAventis Pharma SA (Sanofi )
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InventorsHERCEND, Thierry, TRIEBEL, Frederic, ROMAN-ROMAN, Sergio, FERRADINI, Laurent
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Granted Patent
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Time in Patent OfficeDays
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Field of Search
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US Class Current424/1.49
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CPC Class CodesA61K 38/00 Medicinal preparations cont...A61P 37/00 Drugs for immunological or ...C07K 14/7051 T-cell receptor (TcR)-CD3 c...C07K 16/2809 against the T-cell receptor...C12N 15/1138 against receptors or cell s...
