POROUS OSTEOIMPLANT
First Claim
Patent Images
1. A porous composite comprising:
- a plurality of particles comprising a bone-derived material, an inorganic material, a bone substitute material, a composite material, or any combination thereof, and a biocompatible polymer, wherein the porous composite comprises at least some pores that result from a supercritical fluid treatment.
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Abstract
The invention is directed toward porous composites for application to a bone defect site to promote new bone growth. The inventive porous composites comprise a biocompatible polymer and a plurality of particles of bone-derived material, inorganic material, bone substitute material or composite material. In certain embodiments, the porous composites are prepared using a method that includes a supercritical fluid (e.g., supercritical carbon dioxide) treatment. The invention also discloses methods of using these composites as bone void fillers.
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Citations
136 Claims
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1. A porous composite comprising:
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a plurality of particles comprising a bone-derived material, an inorganic material, a bone substitute material, a composite material, or any combination thereof, and a biocompatible polymer, wherein the porous composite comprises at least some pores that result from a supercritical fluid treatment. - View Dependent Claims (2, 3, 26, 27, 30, 31, 34, 42, 43, 44, 54, 56, 61, 62, 67, 68, 89, 90, 102, 103, 105, 107, 123)
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4-25. -25. (canceled)
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28-29. -29. (canceled)
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32. (canceled)
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33. (canceled)
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35-41. -41. (canceled)
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45-53. -53. (canceled)
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57-60. -60. (canceled)
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63-66. -66. (canceled)
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69-88. -88. (canceled)
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91-101. -101. (canceled)
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104. (canceled)
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108-122. -122. (canceled)
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124-134. -134. (canceled)
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135. A porous composite comprising:
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a plurality of particles comprising a bone-derived material, an inorganic material, a bone substitute material, a composite material, or any combination thereof; and
a biocompatible polymer, wherein the porous composite has a density of between about 1.6 g/cm3 and about 0.05 g/cm3.
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136-231. -231. (canceled)
Specification