Medical Devices

• US 20080071348A1
• Filed: 09/13/2007
• Published: 03/20/2008
• Est. Priority Date: 09/15/2006
• Status: Abandoned Application

• Current Assignee: Boston Scientific Scimed (Boston Scientific Corporation)
• Original Assignee: Boston Scientific Scimed (Boston Scientific Corporation)
• Inventors: Miller, Matthew, Boismier, Dennis A., Kuehling, Michael
• Application Number:
  US11/854,960
• Publication Number:
  US 20080071348A1
• Time in Patent Office: Days
• US Class Current: 623/1.15
• CPC Class Codes: A61F 2/91 made from perforated sheet material or tubes, e.g. perforated by laser cuts or etched holes
• CPC Class Codes: A61F 2/915 with bands having a meander structure, adjacent bands being connected to each other
• CPC Class Codes: A61F 2002/9155 Adjacent bands being connected to each other
• CPC Class Codes: A61F 2002/91575 connected peak to trough
• CPC Class Codes: A61F 2210/0004 bioabsorbable
• CPC Class Codes: A61F 2230/0054 V-shaped
• CPC Class Codes: A61F 2250/003 differing in adsorbability or resorbability, i.e. in adsorption or resorption time
• CPC Class Codes: A61F 2250/0054 differing in corrosion resistance
• CPC Class Codes: A61F 2250/0068 the pharmaceutical product being in a reservoir
• CPC Class Codes: A61F 2250/0071 breakable or frangible
• CPC Class Codes: A61L 2300/00 Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
• CPC Class Codes: A61L 31/022 Metals or alloys
• CPC Class Codes: A61L 31/128 containing other specific inorganic fillers not covered by A61L31/126 or A61L31/127
• CPC Class Codes: A61L 31/146 Porous materials, e.g. foams or sponges
• CPC Class Codes: A61L 31/16 Biologically active materials, e.g. therapeutic substances A61L31/047 takes precedence

Abstract

Medical devices, such as endoprostheses, and methods of making the devices are disclosed.

Claims

1. An endoprosthesis, comprising a generally tubular member comprising a biocrodible foam including a first metal.

2. The endoprosthesis of claim 1, wherein the generally tubular member further comprises a material that is non-bioerodible.

3. The endoprosthesis of claim 1, wherein the generally tubular member further comprises a second metal.

4. The endoprosthesis of claim 3, wherein the bioerodible foam includes pores, and the second metal is disposed within the pores.

5. The endoprosthesis of claim 1, wherein the generally tubular member further comprises a polymer.

6. The endoprosthesis of claim 5, wherein the polymer is biocrodible.

7. The endoprosthesis of claim 5, wherein the bioerodible foam includes pores, and the polymer is disposed within the pores.

8. The endoprosthesis of claim 1, wherein the first metal is selected from the group consisting of iron, magnesium, zinc, aluminum, and combinations thereof.

9. The endoprosthesis of claim 1, wherein the first metal comprises iron.

10. The endoprosthesis of claim 1, wherein the first metal comprises magnesium.

11. The endoprosthesis of claim 1, wherein the bioerodible foam has a volume and the bioerodible foam includes pores that occupy at least about five percent of the volume of the bioerodible foam.

12. The endoprosthesis of claim 1, wherein the bioerodible foam has a volume and the bioerodible foam includes pores that occupy at most about 95 percent of the volume of the bioerodible foam.

13. The endoprosthesis of claim 1, further comprising a therapeutic agent.

14. An endoprosthesis, comprising:

a generally tubular member comprising a bioerodible metal and having a first region including a least one hole and a second region that does not include any holes,

wherein both the first region and the second region include the bioerodible metal.

15. The endoprosthesis of claim 14, wherein the generally tubular member comprises a connector including at least one of the first region and the second region.

16. The endoprosthesis of claim 14,wherein the generally tubular member comprises a band including at least one of the first region and the second region.

17. The endoprosthesis of claim 14, wherein the bioerodible metal is selected from the group consisting of iron, magnesium, zinc, aluminum, and combinations thereof.

18. A method of making an endoprosthesis comprising a generally tubular member, the method comprising:

heating a powder comprising a bioerodible metal to form the generally tubular member.

19. The method of claim 18, wherein the biocrodible metal is selected from the group consisting of iron, magnesium, zinc, aluminum, and combinations thereof.

20. A method of making an endoprosthesis comprising a generally tubular member, the method comprising:

treating a bioerodible foam comprising a first metal to form the generally tubular member.

21. The method of claim 20, wherein treating a bioerodible foam comprising a first metal to form the generally tubular member comprises molding the biocrodible foam to form the generally tubular member.

22. The method of claim 20, wherein the generally tubular member includes a generally tubular portion, and treating a bioerodible foam comprising a first metal to form the generally tubular member comprises coating the generally tubular portion with the biocrodible foam.

23. The method of claim 20, wherein the first metal is selected from the group consisting of iron, magnesium, zinc, aluminum, and combinations thereof.

24. The method of claim 20, further comprising combining the biocrodible foam with a second metal.

25. The method of claim 24, wherein the bioerodible foam includes pores, and combining the foam with a second metal comprises infiltrating the pores with the second metal.

26. The method of claim 20, further comprising combining the bioerodible foam with a polymer.

27. The method of claim 26, wherein the bioerodible foam includes pores, and combining the biocrodible foam with a polymer comprises infiltrating the pores with the polymer.

28. The method of claim 20, further comprising adding a therapeutic agent to the generally tubular member.

29. A method of making an endoprosthesis comprising a generally tubular member, the method comprising:

forming at least one hole in a first region of the generally tubular member so that the first region includes the at least one hole and a second region of the generally tubular member does not include any holes,

wherein the first region of the generally tubular member includes a biocrodible metal.

30. The method of claim 29, wherein the second region includes the bioerodible metal.

31. The method of claim 29, wherein the bioerodible metal is selected from the group consisting of iron, magnesium, zinc, aluminum, and combinations thereof.